2-(benzhydryloxy)benzoic acid | 71280-68-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(benzhydryloxy)benzoic acid
• 英文别名: 2-Benzhydryloxy-benzoesaeure；2-Benzhydryloxybenzoic acid；2-benzhydryloxybenzoic acid
• CAS: 71280-68-7
• 化学式: C₂₀H₁₆O₃
• 分子量: 304.345
• InChiKey: XOMUXDXZDAAYBD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  二苯甲醇 在 1,8-二氮杂双环[5.4.0]十一碳-7-烯 作用下， 以 二氯甲烷 为溶剂， 反应 18.0h， 生成 2-(benzhydryloxy)benzoic acid 、 benzhydryl 2-(benzhydryloxy)benzoate
  参考文献：
  名称：

  Convenient Formation of Diphenylmethyl Esters Using Diphenylmethyl Trichloroacetimidate

  摘要：

  Diphenylmethyl trichloroacetimidate is a useful reagent for the protection of carboxylic acids as their corresponding diphenylmethyl esters. These esterifications proceed rapidly without the need for an added catalyst or promoter. A variety of carboxylic acid substrates undergo esterification in excellent yields with the trichloroacetimidate reagent, including substrates possessing acid- or base-sensitive functionality. Protection of a carboxylic acid with a highly enolizable alpha-stereocenter using diphenylmethyl imidate was also accomplished without racemization.

  DOI：

  10.1055/s-0033-1340293

文献信息

• JPH09309803A
  申请人：——

  公开号：JPH09309803A

  公开（公告）日：1997-12-02
• Convenient Formation of Diphenylmethyl Esters Using Diphenylmethyl Trichloroacetimidate
  作者：John Chisholm、Arijit Adhikari、Jigisha Shah、Kyle Howard、Christopher Russo、Daniel Wallach、Matthew Linaburg

  DOI：10.1055/s-0033-1340293

  日期：——

  Diphenylmethyl trichloroacetimidate is a useful reagent for the protection of carboxylic acids as their corresponding diphenylmethyl esters. These esterifications proceed rapidly without the need for an added catalyst or promoter. A variety of carboxylic acid substrates undergo esterification in excellent yields with the trichloroacetimidate reagent, including substrates possessing acid- or base-sensitive functionality. Protection of a carboxylic acid with a highly enolizable alpha-stereocenter using diphenylmethyl imidate was also accomplished without racemization.