thiamine dilauryl sulfate | 129031-50-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: thiamine dilauryl sulfate
• 英文别名: thiamine; dodecyl sulfate；Thiamin; Dodecylsulfat；Thiamine lauryl sulphate；2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol;dodecyl sulfate
• CAS: 129031-50-1
• 化学式: C₁₂H₁₇N₄OS*C₁₂H₂₅O₄S
• 分子量: 530.753
• InChiKey: MTXXFVINBMMRFR-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  3.99
• 重原子数：
  35
• 可旋转键数：
  15
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  179
• 氢给体数：
  2
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  sodium dodecyl-sulfate 、 盐酸硫胺 以 水 为溶剂， 反应 1.0h， 以93.5%的产率得到thiamine dilauryl sulfate
  参考文献：
  名称：

  유기용매를 사용하지 않는 티아민 라우릴 황산염 제조방법

  摘要：

  本发明涉及一种无机溶剂制备硫胺硫酸十辛盐的方法，具体包括利用水作为溶剂，通过使硫酸十辛酯钠和硫胺素盐酸盐发生反应，然后结晶和过滤，再通过热水洗涤的步骤来制备高纯度的硫胺硫酸十辛盐，而不使用有机溶剂的方法，以及由此方法制备的硫胺硫酸十辛盐粉末，包括乳化剂、中链脂肪酸、甘油和乙醇等，从而提高乳液制剂的溶解度，以及关于该制剂的制备方法。根据本发明，可以高效地制备出高收率、高纯度的硫胺硫酸十辛盐，而无需使用有机溶剂。因此，相比传统方法，可以大大改善环境污染问题，并且还有助于改善操作人员的工作环境。此外，根据本发明，硫胺硫酸十辛盐可以在含有大量水的材料中最小化沉淀并保持稳定，从而可以更广泛地应用于各种用途。

  公开号：

  KR101753357B1

文献信息

• UTILIZATION OF RARE SUGARS IN PLANT OR MICROORGANISM
  申请人：National University Corporation Kagawa University

  公开号：EP1759584A1

  公开（公告）日：2007-03-07

  [OBJECT] To provide an agricultural chemical and the like with the use of an effect of inducing systemic acquired resistance in a plant. To provide a growth inhibitor of not only a plant pathogenic bacterium but also a harmful microorganism. [MEANS FOR RESOLUTION] Utilization of a rare sugar for inducing systemic acquired resistance in a plant or inhibiting the growth of a microorganism. Utilization thereof as an agricultural chemical with the use of the effect of inducing systemic acquired resistance in a plant, a plant disease inhibitor, an inducer of a plant growth regulatory factor (i.e., an inducer of plant hormone-like actions consisting of disease resistance, insect resistance, fruit maturation, breaking of dormancy, regulation of germination, drying resistance, and other than this, resistance to environmental stresses such as low temperature resistance, high temperature resistance, salt resistance and heavy metal resistance and promotion of flowering) and a microorganism growth inhibitor. The rare sugar is an aldose (D-allose, D-altrose or L-galactose) or a ketose (D-psicose or a mixture of D-psicose and D-fructose).

  目的 提供一种具有诱导植物系统性获得抗性效果的农用化学品等。提供一种不仅能抑制植物病原菌生长，还能抑制有害微生物生长的抑制剂。 [解决方法］ 利用稀有糖类诱导植物产生系统获得性抗性或抑制微生物生长。将其用作具有诱导植物的系统获得性抗性、植物病害抑制剂、植物生长调节因子诱导剂（即由抗病、抗虫、果实成熟、打破休眠、调节发芽、抗干燥以及除此以外的抗低温、抗高温、抗盐和抗重金属等环境胁迫以及促进开花等植物激素样作用的诱导剂）和微生物生长抑制剂的效果的农业化学品。稀有糖是醛糖（D-阿洛糖、D-阿洛糖或 L-半乳糖）或酮糖（D-木糖或 D-木糖和 D-果糖的混合物）。
• SOFT CAPSULE COATING
  申请人：Fuji Capsule Co., Ltd.

  公开号：EP3023096A1

  公开（公告）日：2016-05-25

  Provided are a plant-derived soft capsule shell having a high shell sheet strength, a good adhesive property, and excellent shell performance, and a soft capsule. The soft capsule shell comprises: (A) iota carrageenan; and (B) a starch dispersion obtained by ultrasonically treating a starch paste solution.

  本发明提供了一种植物提取的软胶囊壳，它具有较高的壳片强度、良好的粘合性和优异的壳性能，还提供了一种软胶囊。软胶囊壳包括：(A) 碘代卡拉胶；(B) 通过超声波处理淀粉糊溶液得到的淀粉分散液。
• SOFT CAPSULE COATING FILM
  申请人：Fuji Capsule Co., Ltd.

  公开号：EP3202395A1

  公开（公告）日：2017-08-09

  Provided are a plant-derived soft capsule shell having high shell sheet strength, good adhesive property, and good shell performance, and a soft capsule. A soft capsule shell comprising: (A) iota carrageenan; and (B) waxy corn starch having undergone a heat-moisture treatment in the presence of a salt, the soft capsule shell having a content mass ratio [(A)/(B)] of the component (A) to the component (B) of 0.4 to 3, the soft capsule shell having a content mass ratio [carrageenan/starch] of carrageenan including the component (A) to starch including the component (B) of 0.29 to 1.

  本发明提供了一种植物提取的软胶囊壳，它具有较高的壳片强度、良好的粘合性和良好的壳性能，还提供了一种软胶囊。 一种软胶囊壳，包括：(A) 异位卡拉胶；和(B) 在盐存在下经过热湿处理的蜡质玉米淀粉，软胶囊壳中(A)组分与(B)组分的质量比[(A)/(B)]为 0.4 至 3，软胶囊壳中包括(A)组分的卡拉胶与包括(B)组分的淀粉的质量比[卡拉胶/淀粉]为 0.29 至 1。
• COMPOSITION FOR SOFT CAPSULE COATING
  申请人：Fuji Capsule Co., Ltd.

  公开号：EP3332774A1

  公开（公告）日：2018-06-13

  When preparing a soft capsule shell by forming a film from a composition for a soft capsule shell comprising a base containing either gelatin or a mixture of starch and carrageenan as a main component and a plasticizer containing sorbitol, maltitol and glycerin as main components, it is possible to provide a soft capsule in which the soft capsule shell thereof does not easily soften and the surface of the soft capsule shell is resistant to adherence and which has excellent gloss and transparency even if the plasticizer contains glycerin.

  软胶囊壳的主要成分是明胶或淀粉和卡拉胶的混合物，增塑剂的主要成分是山梨醇、麦芽糖醇和甘油，在使用这种软胶囊壳用组合物形成薄膜制备软胶囊壳时，可以提供一种软胶囊，即使增塑剂中含有甘油，其软胶囊壳也不易软化，软胶囊壳表面不易附着，具有良好的光泽度和透明度。
• SOFT CAPSULE FILM COMPOSITION
  申请人：Fuji Capsule Co., Ltd.

  公开号：EP3785707A1

  公开（公告）日：2021-03-03

  A soft capsule film composition, comprising: (A) a native gellan gum; (B) one or more hydrophilic polysaccharides; (C) a starch or modified starch; (D) a plasticizer; and (E) water, wherein a gelling agent other than the native gellan gum and the one or more hydrophilic polysaccharides is not an essential component. The soft capsule film composition shortens drying time at room temperature, suppresses the stickiness of the surface of a film sheet, imparts film sheet strength which can withstand continuous production in factory manufacturing with a rotary die filling machine or the like, and enables the manufacture of a good soft capsule with high adhesiveness. For this reason, the soft capsule produced using the soft capsule film composition can be utilized for various uses such as drugs, quasi drugs, cosmetics, and foods.

  一种软胶囊薄膜组合物，包括：(A) 一种原生结冷胶；(B) 一种或多种亲水多糖；(C) 淀粉或改性淀粉；(D) 增塑剂；以及 (E) 水，其中除原生结冷胶和一种或多种亲水多糖之外的胶凝剂并非必要成分。该软胶囊薄膜组合物可缩短室温下的干燥时间，抑制薄膜片表面的粘性，赋予薄膜片强度，使其在使用旋转模头灌装机或类似设备的工厂制造中能够承受连续生产，并能制造出具有高粘合性的优质软胶囊。因此，使用该软胶囊薄膜组合物生产的软胶囊可用于药物、准药物、化妆品和食品等各种用途。