Glyceryl laurate 1,2-diacetate | 120602-36-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: Glyceryl laurate 1,2-diacetate
• 英文别名: 2,3-diacetyloxypropyl undecanoate
• CAS: 120602-36-0
• 化学式: C₁₈H₃₂O₆
• 分子量: 344.4
• InChiKey: YHHFOPSYEFUIOE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  24
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  78.9
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• Process
  申请人：Wiebe Lars

  公开号：US20120214919A1

  公开（公告）日：2012-08-23

  There is provided a process for the preparation of a compound having the formula (I) wherein R 1 , R 2 and R 3 are independently selected from hydrogen and acyl groups, wherein at least one of R 1 , R 2 and R 3 is a branched chain long acyl group of the formula (II) wherein n is from 9 to 21 and m is 2n, and wherein p is from 0 to 4 wherein the other of R 1 , R 2 and R 3 are selected from short acyl groups of the formula (III) wherein q is from 0 to 4 the process comprising the steps of: (1) providing an unsaturated compound having the formula (I) wherein R 1 , R 2 and R 3 are independently selected from (a) hydrogen, (b) unsaturated long acyl group of the formula (IV) wherein x is from 0 to 3, and wherein n is from 9 to 21 and m is 2n−1−x, 2n−3−x or 2n−5−x;and (c) short acyl groups of the formula (III) wherein q is from 0 to 4 wherein at least one of R 1 , R 2 and R 3 is an unsaturated long acyl group; and (2) if at least one of R 1 , R 2 and R 3 is hydrogen, optionally acylating the compound; and (3a) (i) hydroxylating the unsaturated long acyl group, to provide a hydroxy long acyl group of the formula (V) wherein y is from 1 to 4, n is from 9 to 21 and m is 2n−1−y, 2n−1−y or 2n−3−y, and (ii) acylating the hydroxy long acyl group to provide a branched long acyl group of the formula (VI) wherein z is from 1 to 4, n is from 9 to 21 and m is 2n+1−z, 2n−1−z or 2n−3−z, and wherein p is from 0 to 4; or (3b) reacting the unsaturated long acyl group with a carboxylic acid of the formula (VII) to provide a branched long acyl group of the formula (VI) wherein z is from 1 to 4, n is from 9 to 21 and m is 2n+1−z, 2n−1−z or 2n−3−z, and wherein p is from 0 to 4.
• US8846793B2
  申请人：——

  公开号：US8846793B2

  公开（公告）日：2014-09-30