3-dimethylcarbamoyloxy-1-methyl-pyridinium; chloride | 7681-22-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 3-dimethylcarbamoyloxy-1-methyl-pyridinium; chloride
• 英文别名: Pyridostigmine chloride；(1-methylpyridin-1-ium-3-yl) N,N-dimethylcarbamate;chloride
• CAS: 7681-22-3
• 化学式: C₉H₁₃N₂O₂*Cl
• 分子量: 216.667
• InChiKey: TYXYRYORUZYJDX-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -2.42
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  33.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3-羟基吡啶 在 三乙胺 、 甲苯 、 苯 作用下， 生成 3-dimethylcarbamoyloxy-1-methyl-pyridinium; chloride
  参考文献：
  名称：

  Some Derivatives of 3-Pyridol with Parasympathomimetic Properties¹

  摘要：

  DOI：

  10.1021/ja01147a099

文献信息

• Novel quarternary ammonium compositions coupled with facilitating anions and their use in kits, as well as their use in preventing and treating certain conditions
  申请人：——

  公开号：US20030065015A1

  公开（公告）日：2003-04-03

  This invention is directed to novel pharmaceutical compositions and kits comprising quaternary ammonium salts as the active ingredient and facilitating anions for their absorption into the bloodstream and transportation to the end sites, as well as methods which use such compositions and kits for preventing and/or treating conditions for which the drugs are used to treat.

  本发明涉及新型药物组合物和试剂盒，其中包括作为活性成分的季铵盐和促进其吸收进入血液并运输到最终部位的阴离子，以及使用这种组合物和试剂盒来预防和/或治疗药物用于治疗的病症的方法。
• NOVEL QUATERNARY AMMONIUM COMPOSITIONS COUPLED WITH FACILITATING ANIONS AND THEIR USE IN KITS, AS WELL AS THEIR USE IN PREVENTING AND TREATING CERTAIN CONDITIONS
  申请人：Bacaner, Marvin B.

  公开号：EP1390032A2

  公开（公告）日：2004-02-25
• EP1390032A4
  申请人：——

  公开号：EP1390032A4

  公开（公告）日：2004-12-29
• [EN] NOVEL QUATERNARY AMMONIUM COMPOSITIONS COUPLED WITH FACILITATING ANIONS AND THEIR USE IN KITS, AS WELL AS THEIR USE IN PREVENTING AND TREATING CERTAIN CONDITIONS<br/>[FR] NOUVELLES COMPOSITIONS D'AMMONIUM QUATERNAIRE COUPLEES AVEC DES ANIONS AUXILIAIRES, UTILISATIONS DE CELLES-CI DANS DES KITS ET UTILISATION DE CELLES-CI POUR PREVENIR ET TRAITER CERTAINES PATHOLOGIES
  申请人：BACANER MARVIN B

  公开号：WO2002092003A2

  公开（公告）日：2002-11-21

  This invention is directed to novel pharmaceutical compositions and kits comprising quaternary ammonium salts as the active ingredient and facilitating anions for their absorption into the bloodstream and transportation to the end sites, as well as methods which use such compositions and kits for preventing and/or treating conditions for which the drugs are used to treat.