5-methyl-N-vinyl-2-pyrrolidon | 4854-35-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: 5-methyl-N-vinyl-2-pyrrolidon
• 英文别名: 5-methyl-1-vinyl-pyrrolidin-2-one；5-Methyl-1-vinyl-pyrrolidin-2-on；N-vinyl-5-methyl-2-pyrrolidone；1-Ethenyl-5-methylpyrrolidin-2-one
• CAS: 4854-35-7
• 化学式: C₇H₁₁NO
• 分子量: 125.17
• InChiKey: HQGPZXPTJWUDQR-UHFFFAOYSA-N

物化性质

• 沸点：
  90-95 °C(Press: 5 Torr)
• 密度：
  1.0118 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 氢氧化钾 、 苯 作用下， 生成 5-methyl-N-vinyl-2-pyrrolidon
  参考文献：
  名称：

  Hayashi; Hachihama, Kogyo Kagaku zasshi / Journal of the Society of Chemical Industry, 1954, vol. 57, p. 127

  摘要：

  DOI：

文献信息

• PRODUCTION OF OPHTHALMIC DEVICES BASED ON PHOTO-INDUCED STEP GROWTH POLYMERIZATION
  申请人：Medina Arturo Norberto

  公开号：US20110269869A1

  公开（公告）日：2011-11-03

  The invention provide a new lens curing method for making hydrogel contact lenses. The new lens curing method is based on actinically-induced step-growth polymerization. The invention also provides hydrogel contact lenses prepared from the method of the invention and fluid compositions for making hydrogel contact lenses based on the new lens curing method. In addition, the invention provide prepolymers capable of undergoing actinically-induced step-growth polymerization to form hydrogel contact lenses.

  这项发明提供了一种新的透镜固化方法，用于制造水凝胶隐形眼镜。这种新的透镜固化方法基于光引发的步聚合反应。该发明还提供了通过该发明方法制备的水凝胶隐形眼镜，以及基于新的透镜固化方法制造水凝胶隐形眼镜的液体组合物。此外，该发明提供了能够经历光引发的步聚合反应形成水凝胶隐形眼镜的预聚合物。
• IONIC COMPOUND, COMPOSITION, CURED MATERIAL, HYDROGEL AND OPHTHALMIC LENS
  申请人：Satake Kohsuke

  公开号：US20130202551A1

  公开（公告）日：2013-08-08

  An ionic compound capable of providing a cured material having superior antibacterial property and oxygen permeability, and a composition containing the ionic compound, and a cured material, a hydro gel and an ophthalmic lens which have long-term sustainable antibacterial property and superior oxygen permeability. The ionic compound is represented by the following formula (1): In formula (1), P represents a polymerizable functional group. Q + represents a cationic group: Z represents an n-valent siloxanyl group in which the total atomic weight of a group of constituent atoms is no less than 70 and no greater than 1,000; X m− represents an m-valent anion; and n is an integer of 1 to 10, where provided that n is no less than 2, a plurality of P3 and Q + 3 are each independently as defined above.

  一种离子化合物，能够提供具有优越抗菌性能和氧透性的固化材料，以及含有该离子化合物的组合物，以及具有长期可持续抗菌性能和优越氧透性的固化材料、水凝胶和眼镜片。该离子化合物由以下式（1）表示： 在式（1）中，P代表可聚合的功能基团。Q + 代表阳离子基团：Z代表一个n价硅氧烷基团，其中构成原子的总原子量不小于70且不大于1,000；X m− 代表m价阴离子；n为1至10的整数，其中n不小于2时，多个P3和Q + 3分别独立定义如上所述。
• COPOLYMERS AND COMPOSITIONS WITH ANTI-ADHESIVE AND ANTIMICROBIAL PROPERTIES
  申请人：BASF SE

  公开号：US20160235062A1

  公开（公告）日：2016-08-18

  The invention relates to a copolymer exhibiting both antimicrobial and anti-adhesive properties as well as to a hydrogel. Said hydrogel is obtained from the inventive copolymer and a substrate. Another part of the invention is a process for making the hydrogel, as well as different uses of the inventive copolymer as well as of the hydrogel.

  该发明涉及一种既具有抗菌和抗粘附性能的共聚物，又涉及一种水凝胶。所述水凝胶是由该创新共聚物和基质制得的。该发明的另一部分是制备水凝胶的方法，以及该创新共聚物和水凝胶的不同用途。
• [EN] PROCESS FOR IMPROVED OPIOID SYNTHESIS<br/>[FR] PROCÉDÉ POUR AMÉLIORER LA SYNTHÈSE D'OPIOÏDES
  申请人：RHODES TECHNOLOGIES

  公开号：WO2014013311A1

  公开（公告）日：2014-01-23

  Compounds and compositions for use as starting materials or intermediate materials in the preparation of opioids including, e.g., oxycodone base and/or an oxycodone salt; processes for preparing these compounds and compositions; uses of these compounds and compositions in the preparation of APIs and pharmaceutical dosage forms; and uses of said APIs and pharmaceutical dosage forms in the treatment of medical conditions.

  用于制备阿片类药物的起始物或中间物的化合物和组合物，例如，羟考酮基和/或羟考酮盐；制备这些化合物和组合物的过程；这些化合物和组合物在制备活性药物成分和制药剂量形式中的用途；以及这些活性药物成分和制药剂量形式在治疗医疗状况中的用途。
• [EN] PROCESS FOR IMPROVED OXYCODONE SYNTHESIS<br/>[FR] PROCÉDÉ POUR UNE MEILLEURE SYNTHÈSE DE L'OXYCODONE
  申请人：RHODES TECHNOLOGIES

  公开号：WO2015107471A1

  公开（公告）日：2015-07-23

  Processes for preparing oxycodone are provided. Said processes encompass a step which is a hydrogenation of an 14-hydroxycodeinone salt in the presence of trifluoroacetic acid and/or a glycol.

  提供了制备羟考酮的过程。所述过程包括在三氟乙酸和/或乙二醇存在下对14-羟基可待因盐进行氢化的步骤。