1-bromo-6-chlorohex-2-ene | 85235-99-0

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氯化物
• 英文名称: 1-bromo-6-chlorohex-2-ene
• 英文别名: (2E)-6-chloro-2-hexenyl bromide；(E)-1-bromo-6-chlorohex-2-ene
• CAS: 85235-99-0
• 化学式: C₆H₁₀BrCl
• 分子量: 197.502
• InChiKey: SDWCAMZLMGDXEO-HNQUOIGGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  8
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1-bromo-6-chlorohex-2-ene 在 乙酸铵 、 对甲苯磺酸 、 锌 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 24.0h， 生成 (E,6R)-12-chloro-1-phenylmethoxydodec-8-en-6-ol
  参考文献：
  名称：

  醛通过烯丙基转移反应的高度对映选择性Alk-2-烯基化。

  摘要：

  DOI：

  10.1002/anie.200390327

文献信息

• Pentadienyl dithiocarbamate as a 1,5-dianion equivalent. Versatile reagent for polyene synthesis
  作者：Toshio Hayashi、Isaburo Hori、Takeshi Oishi

  DOI：10.1021/ja00347a072

  日期：1983.5
• HAYASHI, TOSHIO;HORI, ISABURO;OISHI, TAKESHI, J. AMER. CHEM. SOC., 1983, 105, N 9, 2909-2911
  作者：HAYASHI, TOSHIO、HORI, ISABURO、OISHI, TAKESHI

  DOI：——

  日期：——
• ORGANOHALOGEN COMPOUND HAVING CONJUGATED DOUBLE BOND, PROCESS FOR PREPARING ACETATE COMPOUND AND ALCOHOL COMPOUND THEREOF, AND COMPOUND USED TO SYNTHESIZE THE ORGANOHALOGEN COMPOUND
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：US20240174701A1

  公开（公告）日：2024-05-30

  The present invention relates to a process for preparing an organohalogen compound of the following general formula (5), wherein R 2 represents a linear, branched, or aromatic monovalent hydrocarbon group having 1 to 10 carbon atoms, n is the number of methylene groups of 1 to 10, and X 2 represents a halogen atom, the process comprising: obtaining a reaction product mixture by subjecting a (ω-halo-2-alkenyl)triphenylphosphonium halide compound of the following general formula (1), wherein n is as defined for the general formula (5) above, X 1 and X 2 represent, independently of each other, a halogen atom, and Ph represents a phenyl group, to a phosphorus ylide preparation reaction with an alkali metal alkoxide of the following general formula (3), wherein R 1 represents a linear or branched alkyl group having 1 to 6 carbon atoms, and M represents an alkali metal atom, in the presence of a lithium halide of the following general formula (2), wherein X 3 represents a halogen atom, and then subjecting the aforesaid reaction product mixture to a Wittig reaction with an aldehyde compound of the following general formula (4), wherein R 2 is as defined for the general formula (5) above, to form the organohalogen compound of the general formula (5) above.
• Highly Enantioselective Alk-2-enylation of Aldehydes through an Allyl-Transfer Reaction
  作者：Junzo Nokami、Kenta Nomiyama、Seiji Matsuda、Nobuyuki Imai、Kazuhide Kataoka

  DOI：10.1002/anie.200390327

  日期：2003.3.17