5α-cholanic acid-3,6-dione | 6929-22-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 5α-cholanic acid-3,6-dione
• 英文别名: 3,6-dioxo-5α-cholan-24-oic acid；3,6-Dioxo-5α-cholan-24-saeure；3,6-Dioxo-5α-cholansaeure-(24)；3,6-Dioxo-5α-cholansaeure；3,6-Dioxo-5alpha-cholan-24-oic Acid；(4R)-4-[(5S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-3,6-dioxo-2,4,5,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• CAS: 6929-22-2
• 化学式: C₂₄H₃₆O₄
• 分子量: 388.547
• InChiKey: AWINBLVINXVKTE-DLKBGQMWSA-N

物化性质

• 溶解度：
  氯仿：可溶

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  71.4
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  5α-cholanic acid-3,6-dione 生成 methyl 3,6-dioxo-5α-cholan-24-oate
  参考文献：
  名称：

  The determination of stereochemistry at C-5 of 3,6-dioxygenated steroids

  摘要：

  DOI：

  10.1016/0039-128x(69)90001-4
• 作为产物：
  描述：

  猪去氧胆酸 在 chromium(VI) oxide 作用下， 生成 5α-cholanic acid-3,6-dione
  参考文献：
  名称：

  Schenck, 1958, vol. 8, p. 519,522

  摘要：

  DOI：

文献信息

• Sterols. CXXX. 3,6-Diketo Sterols and their Reduction Products^*
  作者：Russell E. Marker、Harry M. Crooks、Eldon M. Jones、Emerson L. Wittbecker

  DOI：10.1021/ja01254a006

  日期：1942.2
• Windaus, Justus Liebigs Annalen der Chemie, 1926, vol. 447, p. 233,253
  作者：Windaus

  DOI：——

  日期：——
• Spatial Variability of Different Fractions of Particulate Matter within an Urban Environment and between Urban and Rural Sites
  作者：Martin Röösli、Charlotte Braun-Fährlander、Nino Künzli、Lucy Oglesby、Gaston Theis、Markus Camenzind、Patrick Mathys、Johannes Staehelin

  DOI：10.1080/10473289.2000.10464161

  日期：2000.7

  The spatial variability of different fractions of particulate matter (PM) was investigated in the city of Basel, Switzerland, based on measurements performed throughout 1997 with a mobile monitoring station at six sites and permanently recorded measurements from a fixed site. Additionally, PM10 measurements from the following year, which were concurrently recorded at two urban and two rural sites, were compared. Generally, the spatial variability of PM4, PM10, and total suspended particulates (TSP) within this Swiss urban environment (area = 36 km2) was rather limited. With the exception of one site in a street canyon next to a traffic light, traffic density had only a weak tendency to increase the levels of PM. Mean PM10 concentration at six sites with different traffic densities was in the range of less than +/- 10% of the mean urban PM10 level. However, comparing the mean PM levels on workdays to that on weekends indicated that the impact of human activities, including traffic, on ambient PM levels may be considerable. Differences in the daily PM10 concentrations between urban and more elevated rural sites were strongly influenced by the stability of the atmosphere. In summer, when no persistent surface inversions exist, differences between urban and rural sites were rather small. It can therefore be concluded that spatial variability of annual mean PM concentration between urban and rural sites in the Basel area may more likely be caused by varying altitude than by distance to the city center.
• Wieland; Dane; Martius, Hoppe-Seyler's Zeitschrift fur Physiologische Chemie, 1933, vol. 215, p. 15,22
  作者：Wieland、Dane、Martius

  DOI：——

  日期：——
• Hodosan,F. et al., Chemische Berichte, 1963, vol. 96, p. 2758 - 2764
  作者：Hodosan,F. et al.

  DOI：——

  日期：——