10-(1H-indol-3-yl-methylene)-anthrone | 68018-34-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 10-(1H-indol-3-yl-methylene)-anthrone
• 英文别名: 10-indol-3-ylmethylene-10H-anthracen-9-one；10-(1H-indol-3-ylmethylidene)anthracen-9-one
• CAS: 68018-34-8
• 化学式: C₂₃H₁₅NO
• 分子量: 321.378
• InChiKey: ISLAPXSQNADRIM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  25
• 可旋转键数：
  1
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  32.9
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  3-吲哚甲醛 、 蒽酮 在 溶剂黄146 作用下， 以 甲苯 为溶剂， 以57%的产率得到10-(1H-indol-3-yl-methylene)-anthrone
  参考文献：
  名称：

  Simple indole-based colorimetric sensors with electron-withdrawing chromophores: Tuning selectivity in anion sensing

  摘要：

  Three simple colorimetric anion sensors (1, 2, and 3) containing anthrone, 1,3-indanedione, and malononitrile as signaling chromophores and an indole binding site have been designed and synthesized. The introduction of electron-withdrawing groups can not only provide chromogenic signal output, but also tune the sensitivity and selectivity of indole-based anion sensors by electron push-pull features. Their anion binding and sensing properties were investigated in detail by dramatic color changes, UV-vis absorption, and H-1 NMR. As results revealed, sensor 1 showed high selectivity for F- over AcO- and H2PO4- with a distinct change in color due to the deprotonation of indole NH group. The excellent selectivity of 1 for F- can be attributed to the fitness in the acidity of its NH-group, which is tuned to be able to distinguish the subtle difference in the affinity of F-, AcO-, and H2PO4- to NH proton. Crown Copyright (C) 2011 Published by Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2011.08.001

文献信息

• BURYAKOVSKAYA V. G.; PRISTUPA V. K.; LAVRUSHIN V. F., VOPR. XIMII I XIM. TEXNOL. RESP.
  作者：BURYAKOVSKAYA V. G.、 PRISTUPA V. K.、 LAVRUSHIN V. F.

  DOI：——

  日期：——