bis(2,2-diphenyl-2-hydroxyethyl)dimethylammonium bromide | 2118-04-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: bis(2,2-diphenyl-2-hydroxyethyl)dimethylammonium bromide
• 英文别名: bis-(2-hydroxy-2,2-diphenyl-ethyl)-dimethyl-ammonium; bromide；Bis-(2-hydroxy-2,2-diphenyl-aethyl)-dimethyl-ammonium; Bromid；Bis(2-hydroxy-2,2-diphenylethyl)-dimethylazanium;bromide
• CAS: 2118-04-9
• 化学式: Br*C₃₀H₃₂NO₂
• 分子量: 518.494
• InChiKey: NVRDOGHAZQZTQL-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  1.94
• 重原子数：
  34
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  二苯甲酮 、 lithium dimethylammonium dimethylide 反应 48.0h， 生成 bis(2,2-diphenyl-2-hydroxyethyl)dimethylammonium bromide
  参考文献：
  名称：

  Controlled formation of tetramethylammonium mono- and diylide

  摘要：

  The reaction of tetramethylammonium bromide with n-butyllithium can selectively yield either trimethylammonium methylide or lithium dimethylammonium dimethylide, depending on the reaction conditions, as shown by C-13-NMR analysis of the deuterium-labelled species resulting from acidic trapping with DCl. So a simple synthesis of mono- or twice-functionalised methylammonium salts is allowed from a very usual starting material. (C) 1999 Elsevier Science S.A. All rights reserved.

  DOI：

  10.1016/s0022-328x(99)00473-8

文献信息

• Wittig; Rieber, Justus Liebigs Annalen der Chemie, 1949, vol. 562, p. 187,190, 192
  作者：Wittig、Rieber

  DOI：——

  日期：——
• Controlled formation of tetramethylammonium mono- and diylide
  作者：Henri-Jean Cristau、Françoise Plénat、Sylvie Bayssade

  DOI：10.1016/s0022-328x(99)00473-8

  日期：1999.12

  The reaction of tetramethylammonium bromide with n-butyllithium can selectively yield either trimethylammonium methylide or lithium dimethylammonium dimethylide, depending on the reaction conditions, as shown by C-13-NMR analysis of the deuterium-labelled species resulting from acidic trapping with DCl. So a simple synthesis of mono- or twice-functionalised methylammonium salts is allowed from a very usual starting material. (C) 1999 Elsevier Science S.A. All rights reserved.