cis,cis,cis-9.12.15-Octadecatrienyl-glyceryl-(1)-ether | 10431-09-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: cis,cis,cis-9.12.15-Octadecatrienyl-glyceryl-(1)-ether
• 英文别名: 3-octadeca-9c,12c,15c-trienyloxy-propane-1,2-diol；3-[(9Z,12Z,15Z)-octadeca-9,12,15-trienoxy]propane-1,2-diol
• CAS: 10431-09-1
• 化学式: C₂₁H₃₈O₃
• 分子量: 338.531
• InChiKey: UROMJAMTNFVTDH-PDBXOOCHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  24
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  49.7
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  linolenyl mesylate 、 丙酮缩甘油 生成 cis,cis,cis-9.12.15-Octadecatrienyl-glyceryl-(1)-ether
  参考文献：
  名称：

  Reactions of Aliphatic Methanesulfonates. I. Syntheses of Long-Chain Glyceryl-(1) Ethers¹

  摘要：

  DOI：

  10.1021/jo01033a065

文献信息

• COSMETIC COMPOSITION CONTAINING 3-O-ALKYL-L-ASCORBIC ACID OR SALT THEREOF
  申请人：Ajinomoto Co., Inc.

  公开号：EP3156040A1

  公开（公告）日：2017-04-19

  The present invention provides a cosmetic composition containing (A) 3-O-alkyl-L-ascorbic acid wherein the alkyl group has 8 - 12 carbon atoms or a salt thereof, (B) one or more kinds of nonionic surfactants selected from the group consisting of polyoxyethylene polyoxypropylene alkyl ether, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene alkyl ether and polyoxyethylene alkenyl ether, and having an HLB value of 12.5 - 17, and (C) one or more kinds of oil agents selected from the group consisting of amino acid ester, dimer acid ester, hydroxy acid ester, alkyl glyceryl ether and alkenyl glyceryl ether, which is superior in solubilization stability, preservation stability and sense of use, and free of time-dependent development of an odor which poses a problem when in use.

  本发明提供了一种化妆品组合物，该组合物含有(A)3-O-烷基-L-抗坏血酸，其中烷基具有 8 - 12 个碳原子或其盐，(B)一种或多种非离子表面活性剂，这些非离子表面活性剂选自由聚氧乙烯聚氧丙烯烷基醚、聚氧乙烯山梨糖醇脂肪酸酯、聚氧乙烯烷基醚和聚氧乙烯烯基醚组成的组，其 HLB 值为 12.5 - 17，以及 (C) 从氨基酸酯、二聚酸酯、羟基酸酯、烷基甘油醚和烯基甘油醚所组成的组中选出的一种或多种油剂，其溶解稳定性、保存稳定性和使用感均优于其他油剂，且在使用时不会随着时间的推移而产生异味。
• Cosmetic composition containing 3-O-alkyl-L-ascorbic acid or salt thereof
  申请人：AJINOMOTO CO., INC.

  公开号：US10322078B2

  公开（公告）日：2019-06-18

  The present invention provides a cosmetic composition containing (A) 3-O-alkyl-L-ascorbic acid wherein the alkyl group has 8-12 carbon atoms or a salt thereof, (B) one or more kinds of nonionic surfactants selected from the group consisting of polyoxyethylene polyoxypropylene alkyl ether, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene alkyl ether and polyoxyethylene alkenyl ether, and having an HLB value of 12.5-17, and (C) one or more kinds of oil agents selected from the group consisting of amino acid ester, dimer acid ester, hydroxy acid ester, alkyl glyceryl ether and alkenyl glyceryl ether, which is superior in solubilization stability, preservation stability and sense of use, and free of time-dependent development of an odor which poses a problem when in use.

  本发明提供了一种化妆品组合物，该组合物含有(A)3-O-烷基-L-抗坏血酸，其中烷基有8-12个碳原子或其盐；(B)一种或多种非离子表面活性剂，这些表面活性剂选自由聚氧乙烯聚氧丙烯烷基醚、聚氧乙烯山梨糖醇脂肪酸酯、聚氧乙烯烷基醚和聚氧乙烯烯基醚组成的组，其HLB值为12.(C) 从氨基酸酯、二聚酸酯、羟基酸酯、烷基甘油醚和烯基甘油醚组成的组中选出的一种或多种油剂，其溶解稳定性、保存稳定性和使用感均优于其他油剂，且在使用时不会随时间产生异味。
• STRUCTURED PHOSPHOLIPIDS FOR TREATING AUTOIMMUNE AND NEURODEGENERATIVE DISEASES
  申请人：BTG INTERNATIONAL LIMITED

  公开号：EP1885377A2

  公开（公告）日：2008-02-13
• METABOLOMIC REVISION OF MAMMALIAN INFANTS
  申请人：Evolve Biosystems Inc.

  公开号：EP3681521A1

  公开（公告）日：2020-07-22
• Biomarkers for Fatty Liver Disease and Methods Using the Same
  申请人：Metabolon, Inc.

  公开号：US20170370954A1

  公开（公告）日：2017-12-28

  Biomarkers of NASH, NAFLD, and fibrosis and methods for diagnosis (or aiding in the diagnosis) of NAFLD, NASH and/or fibrosis are described herein. Additionally, methods of distinguishing between NAFLD and NASH, methods of classifying the stage of fibrosis, methods of determining the severity of liver disease, methods of determining the severity of liver disease or fibrosis, and methods of monitoring progression/regression of NASH, NAFLD, and/or fibrosis are described herein.