l-Menthyl-p-methoxybenzoat | 566916-94-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: l-Menthyl-p-methoxybenzoat
• 英文别名: 4-methoxy-benzoic acid-((1R)-menthyl ester)；4-Methoxy-benzoesaeure-((1R)-menthylester)；[(1S,2R,5S)-5-methyl-2-propan-2-ylcyclohexyl] 4-methoxybenzoate
• CAS: 566916-94-7
• 化学式: C₁₈H₂₆O₃
• 分子量: 290.403
• InChiKey: YILDRXMSKBSBHU-XKQJLSEDSA-N

物化性质

• 沸点：
  386.8±15.0 °C(Predicted)
• 密度：
  1.03±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  D-薄荷醇 、 对甲氧基苯甲酰氯 生成 l-Menthyl-p-methoxybenzoat
  参考文献：
  名称：

  The Isokinetic Temperature of the Acylation ofl-Menthol

  摘要：

  研究人员用对取代的苯甲酰氯和取代的乙酰氯对 l-薄荷醇进行了酰化反应，结果发现，尽管反应完全是 SN2 类型的，但在氯仿中释放电子的取代基会加快反应速率。对这一结果的解释与低等动力学温度有关，反应本身是在该温度以上进行的。我们从构型和溶剂对活化熵的影响角度讨论了这一现象。

  DOI：

  10.1246/bcsj.41.2690

文献信息

• Palladium-Catalyzed Difluorocarbene Transfer Enabled Divergent Synthesis of γ-Butenolides and Ynones from Iodobenzene and Terminal Alkynes
  作者：Heyun Sheng、Zhiwei Chen、Qiuling Song

  DOI：10.1021/jacs.3c13044

  日期：2024.1.17

  Herein, we report a ligand-controlled palladium-catalyzed method that enables the synthesis of ynones and γ-butenolides with excellent regioselectivity from the same set of readily available aryl iodides, aryl acetylenes, and BrCF2CO2K. In this reaction, the [PdII]═CF2 does demonstrate electrophilicity and can generate CO readily when reacting with H2O. It is environmentally friendly and safe compared

  在此，我们报道了一种配体控制的钯催化方法，该方法能够从同一组容易获得的芳基碘化物、芳基乙炔和 BrCF 2 CO 2 K 合成具有优异区域选择性的炔酮和 γ-丁烯内酯。在该反应中， [Pd II ]=CF 2确实表现出亲电性，与 H 2 O 反应时很容易生成 CO。与传统方法相比，它对环境友好且安全，并且当前的方案使我们能够以高产率提供炔酮和 γ-丁烯内酯出色的功能容差。此外，利用该策略还可以与相应的酚和醇获得酯。生物活性化合物后期功能化的成功进一步说明了该方案在材料开发和药物发现中的合成效用。
• The presence of an event in the narrated situation affects its availability to the comprehender
  作者：Rolf A. Zwaan、Carol J. Madden、Shannon N. Whitten

  DOI：10.3758/bf03209350

  日期：2000.11

  Narrative descriptions of events often depart from how these events would have occurred in "real time." For example, narratives often contain time shifts in which events that are irrelevant to the plot are omitted. Zwaan (1996) has shown that these time shifts may affect on-line comprehension. Specifically, they are associated with increases in processing load and a deactivation of previous information. The experiments in the present article show that the situation is more complex. Specifically there is only a deactivation of previous events if they are not assumed to be ongoing after a time shift. Furthermore, explicit discontinuations of events, as in he stopped walking also lead to deactivations when compared with explicit continuations and resumptions.