Brenztraubensaeure-methylester-(2,4-dinitro-phenylhydrazon) | 3618-76-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Brenztraubensaeure-methylester-(2,4-dinitro-phenylhydrazon)
• 英文别名: Methyl pyruvate 2,4-dinitrophenylhydrazone；methyl 2-[(2,4-dinitrophenyl)hydrazinylidene]propanoate
• CAS: 3618-76-6
• 化学式: C₁₀H₁₀N₄O₆
• 分子量: 282.213
• InChiKey: CJGSUGQCFVSSAY-UHFFFAOYSA-N

物化性质

• 熔点：
  179-180 °C
• 沸点：
  412.9±55.0 °C(Predicted)
• 密度：
  1.50±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  142
• 氢给体数：
  1
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  Brenztraubensaeure-methylester-(2,4-dinitro-phenylhydrazon) 在 溴 作用下， 以 二氯甲烷 为溶剂， 反应 16.0h， 以82%的产率得到methyl bromopyruvate 2,4-dinitrophenylhydrazone
  参考文献：
  名称：

  Synthesis of vincamine

  摘要：

  DOI：

  10.1021/jo00145a028
• 作为产物：
  描述：

  丙酮酸甲酯 、 2,4-二硝基苯肼 以 苯 为溶剂， 生成 Brenztraubensaeure-methylester-(2,4-dinitro-phenylhydrazon)
  参考文献：
  名称：

  Reactions of hydroxyl-containing compounds with tert-butyl hydroperoxide in the presence of chromium tetra-tert-butoxide

  摘要：

  Primary and secondary aliphatic, alkylaromatic, cyclic, and organoelement alcohols are efficiently oxidized by tert-butyl hydroperoxide in the presence of both equimolar and catalytic quantities of chromium tetra-tert-butoxide (D(6)De(6), 20A degrees D). alpha-Diols containing tertiary hydroxyl groups interact with this system via oxidative splitting of the carbon scaffold. The oxidation includes the stages of formation and decomposition of chromium-containing peroxy compounds. Further transformations of the carbonyl compounds depend on the structure of radicals in the molecules.

  DOI：

  10.1134/s1070363215110080

文献信息

• A new protocol to synthesize 1,4-dihydropyridines by using 3,4,5-trifluorobenzeneboronic acid as a catalyst in ionic liquid: synthesis of novel 4-(3-carboxyl-1H-pyrazol-4-yl)-1,4-dihydropyridines
  作者：Radhakrishnan Sridhar、Paramasivan T. Perumal

  DOI：10.1016/j.tet.2005.01.008

  日期：2005.2

  liquid mediated facile synthesis of 4-pyrazolyl 1,4-dihydropyridines at room temperature by the cyclocondensation of ethyl 3-aminocrotonate, pyrazole aldehyde and a β-keto ester is reported. The procedure adopted was found to be eco-benign, facile at room temperature and better than the conventional, [bmim]Cl mediated and InCl3 catalysed, [bmim]Cl mediated 1,4-dihydropyridine syntheses.

  据报道，在3,4,5-三氟苯硼酸催化下，离子液体介导的3-氨基巴豆酸乙酯，吡唑醛和β-酮酯的环缩合反应在室温下容易地合成4-吡唑基1,4-二氢吡啶。发现所采用的方法是生态友好的，在室温下容易，并且比常规的[bmim] Cl介导的和InCl 3催化的，[bmim] Cl介导的1，4-二氢吡啶合成更好。
• Specific features of the reaction of vanadyl acetylacetonate with tert-butyl hydroperoxide
  作者：L. P. Stepovik、M. V. Gulenova

  DOI：10.1134/s1070363209080143

  日期：2009.8

  Reaction of vanadyl acetylacetonate with tert-butyl hydroperoxide (benzene, 20 degrees C) at any molar ratio leads to the elimination of ligand and its oxidation mainly to CO2 and acetic acid. At the (acac)(2)VO: t-BuOOH ratio above 1: 10 liberation of oxygen partially in the singlet state takes place.
• �ber halogen- und stickstoffhaltige Derivate aliphatischer Carbons�uren, 5. Mitt.: �ber die Gewinnung von ?-Oximinocarbons�ureestern und ihre �berf�hrung in ?-Ketos�uren
  作者：H. Reinheckel

  DOI：10.1007/bf00908991

  日期：——
• ?-Substituted ?-amino acids
  作者：V. K. Antonov、A. L. Kurts

  DOI：10.1007/bf01179572

  日期：1964.1
• Structural modification of mevinolin
  作者：Ta Jyh Lee、Wilbur J. Holtz、Robert L. Smith

  DOI：10.1021/jo00145a029

  日期：1982.11