phenylhydrazide of D-gluconic acid | 24758-68-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: phenylhydrazide of D-gluconic acid
• 英文别名: D-gluconic acid phenylhydrazide；D-gluconic acid-(N'-phenyl-hydrazide); (d-gluconic acid )-phenylhydrazide；D-Gluconsaeure-(N'-phenyl-hydrazid); (d-Gluconsaeure)-phenylhydrazid；2,3,6-Trimethyl-D-mannonsaeure-phenylhydrazid；2,3-Dimethyl-D-mannonsaeure-phenylhydrazid；D-Gluconsaeure-phenylhydrazid；(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxy-N'-phenylhexanehydrazide
• CAS: 24758-68-7
• 化学式: C₁₂H₁₈N₂O₆
• 分子量: 286.285
• InChiKey: BOJPTTLENHUOHV-CHWFTXMASA-N

物化性质

• 熔点：
  200 °C
• 沸点：
  594.4±50.0 °C(Predicted)
• 密度：
  1.535±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  20
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  142
• 氢给体数：
  7
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  吡啶 、 三苯基氯甲烷 、 phenylhydrazide of D-gluconic acid 生成 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  Helferich; Moog; Juenger, Chemische Berichte, 1925, vol. 58, p. 880

  摘要：

  DOI：
• 作为产物：
  描述：

  葡糖酸 在 盐酸 、 一水合肼 作用下， 以 乙醇 为溶剂， 反应 0.03h， 生成 phenylhydrazide of D-gluconic acid
  参考文献：
  名称：

  MAOS ofD‐Gluconic Acid,D‐Glucono‐1,4‐ and 1,5‐Lactones, Esters, Hydrazides, and Benzimidazoles Thereof

  摘要：

  Microwave-assisted organic synthesis (MAOS) of D-gluconic acid can be efficiently done by oxidation of D- glucose with bromine water, upon irradiation with microwave ( MW). It was also used for the conversion of D-gluconic acid to ethyl D-gluconate, D-glucono-1,4- and 1,5-lactones, gluconyl hydrazide, and gluconyl phenylhydrazide in yields comparable to those obtained by conventional methods, but in much shorter times. A convenient microwave- mediated condensation of D- gluconic acid with o-phenylenediamines provided the respective acyclonucleoside benzimidazole in short time and good yield.[GRAPHICS]

  DOI：

  10.1080/07328300701540258

文献信息

• EL, KHADEM HASSAN S.;CROSSMAN, ARTHUR (JR);BENSEN, DEBRA, CARBOHYDR. RES., 212,(1991) C. 9-11
  作者：EL, KHADEM HASSAN S.、CROSSMAN, ARTHUR (JR)、BENSEN, DEBRA

  DOI：——

  日期：——
• Helferich; Moog; Juenger, Chemische Berichte, 1925, vol. 58, p. 880
  作者：Helferich、Moog、Juenger

  DOI：——

  日期：——
• MAOS of<scp>D</scp>‐Gluconic Acid,<scp>D</scp>‐Glucono‐1,4‐ and 1,5‐Lactones, Esters, Hydrazides, and Benzimidazoles Thereof
  作者：E. S. H. El Ashry、L. F. Awad、H. Abdel Hamid、A. I. Atta

  DOI：10.1080/07328300701540258

  日期：2007.9

  Microwave-assisted organic synthesis (MAOS) of D-gluconic acid can be efficiently done by oxidation of D- glucose with bromine water, upon irradiation with microwave ( MW). It was also used for the conversion of D-gluconic acid to ethyl D-gluconate, D-glucono-1,4- and 1,5-lactones, gluconyl hydrazide, and gluconyl phenylhydrazide in yields comparable to those obtained by conventional methods, but in much shorter times. A convenient microwave- mediated condensation of D- gluconic acid with o-phenylenediamines provided the respective acyclonucleoside benzimidazole in short time and good yield.[GRAPHICS]