2-Hydroxyethyl-dimethyl-[3-(2-methylprop-2-enoylamino)propyl]azanium;chloride | 73170-87-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2-Hydroxyethyl-dimethyl-[3-(2-methylprop-2-enoylamino)propyl]azanium;chloride
• 英文别名: 2-hydroxyethyl-dimethyl-[3-(2-methylprop-2-enoylamino)propyl]azanium;chloride
• CAS: 73170-87-3
• 化学式: C₁₁H₂₃N₂O₂*Cl
• 分子量: 250.769
• InChiKey: UGHDGJHFWYZFKB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.86
• 重原子数：
  16
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  49.3
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  N-(3-二甲氨基丙基)甲基丙烯酰胺 、 2-氯乙醇 以 水 为溶剂， 生成 2-Hydroxyethyl-dimethyl-[3-(2-methylprop-2-enoylamino)propyl]azanium;chloride
  参考文献：
  名称：

  Concentration effects in the nucleophilic reactions of tertiary amines in aqueous solutions. Alkylation of amines with ethylene chlorohydrin

  摘要：

  During the alkylation of tertiary amines with ethylene chlorohydrin in aqueous solutions, the initial rates and degrees of conversion attained within control periods of time showed nonstandard dependences on the initial concentrations of reagents. The character of the concentration dependences depended on the structure of the hydrocarbon fragments and the available sets of functional groups in amines. On the basis of our results and viscosimetric data for the model systems, we assumed that these effects were due to pre-reaction association involving the reagents and products.

  DOI：

  10.1134/s0036024410120113

文献信息

• Compositions comprising superhydrophilic amphiphilic copolymers and methods of use thereof
  申请人：Johnson & Johnson Consumer Companies, Inc.

  公开号：EP2314273A2

  公开（公告）日：2011-04-27

  Provided are compositions comprising a superhydrophilic amphiphilic copolymer and a carrier and composition comprising a superhydrophilic amphiphilic copolymer, a micellar thickener and a carrier.

  提供了由超亲水两亲共聚物和载体组成的组合物，以及由超亲水两亲共聚物、胶束增稠剂和载体组成的组合物。
• Compositions comprising a superhydrophilic amphiphilic copolymer and a micellar thickener
  申请人：Johnson & Johnson Consumer Companies, Inc.

  公开号：EP2314274A2

  公开（公告）日：2011-04-27

  Provided are healthcare compositions comprising a superhydrophilic amphiphilic copolymer, a micellar thickener, and a cosmetically-acceptable or pharmaceutically-acceptable carrier. Also, provided are methods of cleansing or treating a mammal by applying healthcare compositions of the present inventions to the mammalian body.

  本发明提供的保健组合物包含超亲水性两亲共聚物、胶束增稠剂和化妆品可接受或药学可接受的载体。此外，还提供了通过在哺乳动物体内施用本发明的保健组合物来清洁或治疗哺乳动物的方法。
• SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND PROCESSES FOR MAKING THE SAME
  申请人：Akzo Nobel Chemicals International B.V.

  公开号：EP2486063A1

  公开（公告）日：2012-08-15
• SUNSCREEN COMPOSITIONS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS
  申请人：Johnson & Johnson Consumer Inc.

  公开号：EP3349723A1

  公开（公告）日：2018-07-25
• FOAMING SUNSCREEN COMPOSITION CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER
  申请人：Johnson & Johnson Consumer Inc.

  公开号：EP3349863B1

  公开（公告）日：2022-01-19