Prorocentrolide | 117120-34-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: Prorocentrolide
• 英文别名: (10E,12E,23E,47E)-14,18,19,22,31,33,40,41-octahydroxy-2,11,23,47,50-pentamethyl-35-methylidene-26,53,54,55-tetraoxa-6-azaheptacyclo[23.21.5.13,45.117,21.129,32.139,43.02,7]pentapentaconta-6,10,12,23,45,47-hexaen-27-one
• CAS: 117120-34-0
• 化学式: C₅₆H₈₅NO₁₃
• 分子量: 980.3
• InChiKey: XZXZSKRRHGFIQS-YFHRIDBKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  70
• 可旋转键数：
  0
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  228
• 氢给体数：
  8
• 氢受体数：
  14

文献信息

• Method for manufacturing an analysis substrate, and use thereof for detecting toxins
  申请人：Araoz Romulo

  公开号：US10073089B2

  公开（公告）日：2018-09-11

  The présent invention relates to a method for manufacturing an analysis device including torpédo membrane fragments immobilized at the surface thereof, to the resulting analysis device, and to the use of said device for detecting, purifying, and characterizing molécules acting on nicotinic acetylcholine receptors. The présent invention is useful in the field of monitoring seafood, monitoring neurotoxic phytoplankton for the shellfish industry, monitoring the quality of bathing waters along tourist beaches, the field of monitoring fresh water reserves, the field of médical research, the field of the biological analysis and characterization of molécules, e.g., non-radioactive assays of the movement of the ligand-receptor bond on an ELISA-type microplate, thereby enabling compétitive agonists and antagonists of targets to be detected, e.g., of highly sensitive receptors.

  本发明涉及一种制造分析装置的方法，该装置包括固定在其表面的 torpédo 膜片段；本发明还涉及由此产生的分析装置，以及使用所述装置检测、纯化和表征作用于烟碱乙酰胆碱受体的分子。本发明适用于海产品监测、贝类产业神经毒性浮游植物监测、旅游海滩海水质量监测、淡水储备监测、医学研究、分子生物学分析和表征等领域、在酶联免疫吸附试验（ELISA）型微孔板上对配体-受体键的运动进行非放射性检测，从而检测出目标物（如高灵敏度受体）的同性激动剂和拮抗剂。
• DEVICE FOR DETECTING NEUROTOXINS AND PROCESS FOR MANUFACTURE THEREOF
  申请人：Centre National de la Recherche Scientifique CNRS

  公开号：EP3394618A1

  公开（公告）日：2018-10-31
• METHOD FOR MANUFACTURING AN ANALYSIS SUBSTRATE, AND USE THEREOF FOR DETECTING TOXINS
  申请人：Araoz Romulo

  公开号：US20130303405A1

  公开（公告）日：2013-11-14

  The présent invention relates to a method for manufacturing an analysis device including torpédo membrane fragments immobilized at the surface thereof, to the resulting analysis device, and to the use of said device for detecting, purifying, and characterizing molécules acting on nicotinic acetylcholine receptors. The présent invention is useful in the field of monitoring seafood, monitoring neurotoxic phytoplankton for the shellfish industry, monitoring the quality of bathing waters along tourist beaches, the field of monitoring fresh water reserves, the field of médical research, the field of the biological analysis and characterization of molécules, e.g., non-radioactive assays of the movement of the ligand-receptor bond on an ELISA-type microplate, thereby enabling compétitive agonists and antagonists of targets to be detected, e.g., of highly sensitive receptors.
• [EN] DEVICE FOR DETECTING NEUROTOXINS AND PROCESS FOR MANUFACTURE THEREOF<br/>[FR] DÉTECTEUR DE DÉTECTION DE NEUROTOXINES ET SON PROCÉDÉ DE FABRICATION
  申请人：CENTRE NAT DE LA RECH SCIENT - CNRS -

  公开号：WO2017108115A1

  公开（公告）日：2017-06-29

  The present invention relates to a device for detecting neurotoxins, a method for manufacturing an analysis device, and use of an analysis device detecting and quantifying neurotoxins. The present invention finds an application in the medical field and also in food field, in particular in the field of monitoring seafood, in the field of monitoring freshwater reservoirs, in the field of medical research, and in the field of the biological analysis and characterization of molecules.
• [EN] DEVICE FOR DETECTING NEUROTOXINS AND PROCESS FOR MANUFACTURE THEREOF<br/>[FR] DISPOSITIF DE DÉTECTION DE NEUROTOXINES ET SON PROCÉDÉ DE FABRICATION
  申请人：CENTRE NAT DE LA RECH SCIENT - CNRS -

  公开号：WO2017108582A1

  公开（公告）日：2017-06-29

  The present invention relates to a device for detecting neurotoxins or ligands, a method for manufacturing an analysis device, and use of an analysis device detecting and quantifying neurotoxins or ligands. The present invention finds an application in the medical field and also in food field, in particular in the field of monitoring seafood, in the field of monitoring freshwater reservoirs, in the field of medical research, and in the field of the biological analysis and characterization of molecules.