Benzenesulfonic acid;ethanol | 85536-15-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzenesulfonic acid;ethanol
• 英文别名: benzenesulfonic acid;ethanol
• CAS: 85536-15-8
• 化学式: C8H12O4S
• 分子量: 204.25
• InChiKey: GTYQUDGTNAGVIY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.93
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  83
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Heterocyclic Substituted Acardite Derivate and Application Thereof
  申请人：Zhang Aihua

  公开号：US20120053192A1

  公开（公告）日：2012-03-01

  This present invention discloses a heterocyclic substituted acardite derivate and application thereof, namely compounds in the general formula (1) or the general formula (2) or pharmaceutically acceptable salts thereof, wherein A is monosubstituted or polysubstituted quinoline, isoquinoline, quinazoline, pyrrole or pyrimidine, and the substituent is halogen, C 1-5 alkyl, C 1-5 haloalkyl, C 1-5 alkoxy, C 1-5 haloalkoxy, C 1-5 alkylamino, C 1-5 haloalkylamino, amino or nitryl; R 1 is C 1-5 alkyl; R 2 is one or more selected from hydrogen, halogen, alkyl, alkoxy, haloalkyl or haloalkoxy; and R 3 is one or more selected from hydrogen, halogen, alkyl, alkoxy, haloalkyl or haloalkoxy. The compound of the present invention and the pharmaceutically acceptable salt thereof can be used for treating tumor or leukemia.

  本发明公开了一种杂环取代阿卡尔地衍生物及其应用，即通式（1）或通式（2）中的化合物或其药学上可接受的盐，其中A是单取代或多取代的喹啉、异喹啉、喹啉、吡咯或嘧啶，取代基是卤素、C1-5烷基、C1-5卤代烷基、C1-5烷氧基、C1-5卤代烷氧基、C1-5烷基氨基、C1-5卤代烷基氨基、氨基或硝基；R1是C1-5烷基；R2是氢、卤素、烷基、烷氧基、卤代烷基或卤代烷氧基中的一个或多个；R3是氢、卤素、烷基、烷氧基、卤代烷基或卤代烷氧基中的一个或多个。本发明的化合物及其药学上可接受的盐可用于治疗肿瘤或白血病。
• SOLID FORMS OF A COT INHIBITOR COMPOUND
  申请人：Gilead Sciences, Inc.

  公开号：US20210309637A1

  公开（公告）日：2021-10-07

  Disclosed are solid forms of a Cot (cancer Osaka thyroid) inhibitor and corresponding methods of preparation thereof, wherein the Cot inhibitor has the following formula:

  揭示了一种Cot（癌症大阪甲状腺）抑制剂的固体形式及其制备方法，其中该Cot抑制剂具有以下结构式：
• POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH HIGH COMONOMER INCORPORATION
  申请人：Yang Qing

  公开号：US20110201833A1

  公开（公告）日：2011-08-18

  The present techniques relate to catalyst compositions, methods, and polymers encompassing a Group 4 metallocene compound comprising bridged η 5 -cyclopentadienyl-type ligands, typically in combination with a cocatalyst, and an activator. The bridged η 5 -cyclopentadienyl-type ligands are connected by a cyclic substituent.

  这些技术涉及催化剂组合物、方法和聚合物，其中包括一种含有桥联的η5-环戊二烯基型配体的第4族过渡金属烯化合物，通常与协同催化剂和活化剂结合使用。桥联的η5-环戊二烯基型配体通过一个环状取代基连接。
• POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW MELT ELASTICITY
  申请人：CHEVRON PHILLIPS CHEMICAL COMPANY LP

  公开号：US20130245302A1

  公开（公告）日：2013-09-19

  The present techniques relate to catalyst compositions, methods, and polymers encompassing a Group 4 metallocene compound comprising bridging η 5 -cyclopentadienyl-type ligands, typically in combination with a cocatalyst, and a activator. The compositions and methods presented herein include ethylene polymers with low melt elasticity.

  这些技术涉及催化剂组成、方法和聚合物，其中包括一种包含桥联的η5-环戊二烯基型配体的第4族过渡金属烯化合物，通常与协同催化剂和活化剂结合使用。本文介绍的组成物和方法包括具有低熔融弹性的乙烯聚合物。
• Polymerization catalysts for producing high molecular weight polymers with low levels of long chain branching
  申请人：Yang Qing

  公开号：US20070179044A1

  公开（公告）日：2007-08-02

  This invention relates to catalyst compositions, methods, and polymers encompassing at least one Group 4 metallocene compound comprising bridging η 5 -cyclopentadienyl-type ligands, typically in combination with at least one cocatalyst, and at least one activator. The compositions and methods disclosed herein provide ethylene polymers with low levels of long chain branching.

  本发明涉及催化剂组合物、方法和聚合物，其中包括至少一种含有桥式η5-环戊二烯基型配体的第四族过渡金属烯化合物，通常与至少一种协同催化剂和至少一种活化剂相结合。本发明所披露的组合物和方法提供了具有低水平长链支化的乙烯聚合物。