methyl 5-[(anthracen-9-ylmethyl)carbamoyl]pyrrole-2-carboxylate | 1192023-47-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: methyl 5-[(anthracen-9-ylmethyl)carbamoyl]pyrrole-2-carboxylate
• 英文别名: methyl 5-(anthracen-9-ylmethylcarbamoyl)-1H-pyrrole-2-carboxylate
• CAS: 1192023-47-4
• 化学式: C₂₂H₁₈N₂O₃
• 分子量: 358.397
• InChiKey: SSSGLVJONOPGHF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  71.2
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  methyl 5-[(anthracen-9-ylmethyl)carbamoyl]pyrrole-2-carboxylate 、 胍 在 盐酸 作用下， 以 N,N-二甲基甲酰胺 、 水 为溶剂， 反应 36.0h， 以40%的产率得到5-N-(anthracen-9-ylmethyl)-2-N-(diaminomethylidene)-1H-pyrrole-2,5-dicarboxamide;hydrochloride
  参考文献：
  名称：

  A Ratiometric Fluorescent Chemodosimeter with Selective Recognition for Sulfite in Aqueous Solution

  摘要：

  A fluorescent chemodosimeter containing a guanidinio-carbonylpyrrole and a 9-(aminomethyl)anthracene moiety has been synthesized. The sensor exhibits ratiometric fluorescence changes for SO32- over other anions in 90% water/DMSO. The interesting ratiometric fluorescent changes for SO32- are attributed to the fluorescence resonance energy transfer (FRET) and the SO32- complex induced photochemical reaction.

  DOI：

  10.1021/jo9014744
• 作为产物：
  描述：

  1-(9-蒽基)甲胺 、 甲基5-(氯甲酰基)-1H-吡咯-2-羧酸酯 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 以750 mg的产率得到methyl 5-[(anthracen-9-ylmethyl)carbamoyl]pyrrole-2-carboxylate
  参考文献：
  名称：

  A Ratiometric Fluorescent Chemodosimeter with Selective Recognition for Sulfite in Aqueous Solution

  摘要：

  A fluorescent chemodosimeter containing a guanidinio-carbonylpyrrole and a 9-(aminomethyl)anthracene moiety has been synthesized. The sensor exhibits ratiometric fluorescence changes for SO32- over other anions in 90% water/DMSO. The interesting ratiometric fluorescent changes for SO32- are attributed to the fluorescence resonance energy transfer (FRET) and the SO32- complex induced photochemical reaction.

  DOI：

  10.1021/jo9014744

文献信息

• A Ratiometric Fluorescent Chemodosimeter with Selective Recognition for Sulfite in Aqueous Solution
  作者：Yimin Sun、Cheng Zhong、Rui Gong、Honglei Mu、Enqin Fu

  DOI：10.1021/jo9014744

  日期：2009.10.16

  A fluorescent chemodosimeter containing a guanidinio-carbonylpyrrole and a 9-(aminomethyl)anthracene moiety has been synthesized. The sensor exhibits ratiometric fluorescence changes for SO32- over other anions in 90% water/DMSO. The interesting ratiometric fluorescent changes for SO32- are attributed to the fluorescence resonance energy transfer (FRET) and the SO32- complex induced photochemical reaction.