U2TETA | 166532-70-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: U2TETA
• 英文别名: 1,3-Bis(2-aminoethyl)imidazolidin-2-one
• CAS: 166532-70-3
• 化学式: C₇H₁₆N₄O
• 分子量: 172.23
• InChiKey: NJBOQNXSMHSDDZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.4
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  75.6
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  U2TETA 在 水 、 sodium hydroxide 作用下， 220.0~250.0 ℃ 、3.0 MPa 条件下， 反应 8.5h， 生成 三乙烯四胺
  参考文献：
  名称：

  [EN] TWO-STEP PROCESS FOR CONVERTING CYCLIC ALKYLENE UREAS INTO THEIR CORRESPONDING ALKYLENE AMINES
  [FR] PROCÉDÉ EN DEUX ÉTAPES DE CONVERSION D'ALKYLÈNE-URÉES CYCLIQUES EN LEURS ALKYLÈNE-AMINES CORRESPONDANTES

  摘要：

  本发明涉及一种将环状烷基脲转化为相应的烷基胺的过程，包括以下步骤：第一步，在液相中通过与水反应并去除CO2将环状烷基脲转化为相应的烷基胺，以将进料中的5摩尔％至95摩尔％的烷基脲转化为相应的胺；第二步，加入无机碱并将第一步剩余的环状烷基脲与无机碱反应，部分或完全将其转化为相应的烷基胺。发现本发明的两步法使得仍然可以获得高度转化的环状烷基脲，同时使用的强碱明显较少。本发明的过程还表现出比现有技术更高的胺选择性。

  公开号：

  WO2019030193A1
• 作为产物：
  描述：

  DUTETA 在 三乙烯二胺 、 水 作用下， 反应 32.0h， 生成 U2TETA 、 U1TETA
  参考文献：
  名称：

  [EN] PROCESS TO CONVERT CYCLIC ALKYLENE UREAS INTO THEIR CORRESPONDING ALKYLENE AMINES
  [FR] PROCÉDÉ DE CONVERSION D'ALKYLÈNE-URÉES CYCLIQUES EN LEURS ALKYLÈNE-AMINES CORRESPONDANTS

  摘要：

  本发明涉及一种将环状烷基脲转化为相应的烷基胺的过程，其中该过程通过与胺化合物反应来执行，并且该胺化合物包括一级胺、环状二级胺或三级双环胺。

  公开号：

  WO2017137529A1

文献信息

• [EN] PROCESS FOR PREPARING CYCLIC ALKYLENE UREAS<br/>[FR] PROCÉDÉ DE PRÉPARATION D'ALKYLÈNE-URÉES CYCLIQUES
  申请人：AKZO NOBEL CHEMICALS INT BV

  公开号：WO2019030195A1

  公开（公告）日：2019-02-14

  A process for producing a cyclic alkylene urea product of Formula I: in which a compound of Formula II and/or Formula III is contacted in a reaction zone with a compound of Formula IV and/or Formula V and in the presence of one or more carbonyl delivering compounds; in which; R1 is –[A−X−]qR3; R2 is on each occurrence independently selected from H and C1 to C6 alkyl groups which are optionally substituted by one or two groups selected from −OH and −NH2; R3 is on each occurrence independently selected from H and C1 to C6 alkyl groups which are optionally substituted by one or two groups selected from −OH and −NH2; A is on each occurrence independently selected from C1 to C3 alkylene units, optionally substituted by one or more C1 to C3 alkyl groups; X is on each occurrence independently selected from −O−, −NR2−, groups of Formula VI, and groups of Formula VII and p and q are each independently selected from a whole number in the range of from 0 to 8; wherein the compound of Formula II and/or the compound of Formula III are added to a reaction zone comprising compound of Formula IV and/or compound of Formula (V) continuously or semi-continuously over a period of time, or in two or more batches.

  一种生产公式I的环烷基脲产物的方法：在反应区中，将公式II和/或公式III的化合物与公式IV和/或公式V的化合物接触，并在一个或多个羰基供体化合物的存在下进行反应；其中，R1是- [A-X-] qR3; R2在每次出现时独立地选择H和C1到C6烷基，其可以被一个或两个从-OH和-NH2中选择的基团取代；R3在每次出现时独立地选择H和C1到C6烷基，其可以被一个或两个从-OH和-NH2中选择的基团取代；A在每次出现时独立地选择C1到C3烷基单元，其可以被一个或多个C1到C3烷基取代；X在每次出现时独立地选择-O-，-NR2-，公式VI的基团和公式VII的基团；p和q各自独立地选择从0到8的整数；其中，将公式II和/或公式III的化合物连续或半连续地在一段时间内加入包含公式IV和/或公式V的化合物的反应区中，或者分成两个或多个批次加入。
• [EN] PROCESS FOR MANUFACTURING A CYCLIC UREA ADDUCT OF AN ETHYLENEAMINE COMPOUND<br/>[FR] PROCÉDÉ DE FABRICATION DE PRODUIT D'ADDITION D'URÉE CYCLIQUE D'UN COMPOSÉ ÉTHYLÈNEAMINE
  申请人：AKZO NOBEL CHEMICALS INT BV

  公开号：WO2019030191A1

  公开（公告）日：2019-02-14

  The invention pertains to a process for manufacturing a cyclic urea adduct of an ethyleneamine compound, the ethyleneamine compound having a linear -NH-CH2-CH2-NH- group, the process comprising the steps of - in an absorption step contacting a liquid medium comprising an ethyleneamine compound having a linear -NH-CH2-CH2-NH- group with a CO2-containing gas stream at a pressure of 1 -20 bara, resulting in the formation of a liquid medium into which CO2 has been absorbed, - bringing the liquid medium to cyclic urea formation conditions, and in an urea formation step forming cyclic urea adduct of the ethyleneamine compound, urea formation conditions including a temperature of at least 120°C, wherein the total pressure at the end of the urea formation step is at most 20 bara, wherein the temperature in the absorption step is lower than the temperature in the urea formation step. It has been found that the process according to the invention makes it possible to obtain cyclic urea adducts in an efficient manner in the absence of metal-containing catalysts and to perform the process under relatively mild conditions, in particular relatively low pressure. More specifically, by separating the CO2 absorption step from the urea formation step, the CO2 absorption step can be carried out at relatively low temperatures and pressures. And because the CO2 is already present in the system at the beginning of the urea formation step, the pressure in the urea formation step does not need to be high.

  该发明涉及一种制造具有线性-NH-CH2- -NH-基团的乙二胺化合物的环式脲加合物的工艺，该工艺包括以下步骤：-在吸收步骤中，将包含具有线性-NH- - -NH-基团的乙二胺化合物的液体介质与含CO2气流在1-20 bara的压力下接触，导致形成已吸收 的液体介质，-将液体介质带到环式脲形成条件，并在脲形成步骤中形成乙二胺化合物的环式脲加合物，脲形成条件包括至少120°C的温度，在脲形成步骤结束时的总压力最多为20 bara，在吸收步骤中的温度低于脲形成步骤中的温度。发现该发明的工艺使得在无金属催化剂的情况下以相对温和的条件，特别是相对低压下有效地获得环式脲加合物成为可能。更具体地，通过将 吸收步骤与脲形成步骤分离， 吸收步骤可以在相对低温和压力下进行。由于在脲形成步骤开始时系统中已经存在 ，因此脲形成步骤中的压力不需要很高。
• Process for the Synthesis of N-substituted Cyclic Alkylene Ureas
  申请人：Cytec Technology Corp.

  公开号：EP2548869A1

  公开（公告）日：2013-01-23

  The invention relates to a process for the synthesis of N-substituted cyclic alkylene ureas by reacting a multifunctional aliphatic amine A having at least two amino groups which may be primary or secondary, at least one of which is a primary amino group, -NH2, and at least one of which is a secondary amino group, >NH, the other hydrogen group whereof having been substituted by a hydrocarbyl group which in turn may be substituted by a hydroxyl group, or an amino group, or a carboxyl group, or a ketone carbonyl group, or a hydrazide or hydrazone group, or a mercaptan group, and at least one further functional group selected from the group consisting of primary or secondary amino groups and hydroxyl groups, and an aliphatic organic carbonate component C selected from the group consisting of dialkyl carbonates CD and of alkylene carbonates CA.

  本发明涉及一种合成N-取代环状烷基脲的方法，该方法通过反应一种具有至少两个氨基的多功能脂肪族胺A来实现，其中至少一个是一级氨基-NH2，至少一个是二级氨基->NH，其它氢原子被烃基取代，该烃基又可以被羟基、氨基、羧基、酮羰基、肼或肼酮基、巯基取代，同时还包括至少一种来自于一级或二级氨基与羟基的功能基团，以及一种来自于脂肪族有机碳酸酯组分C的反应，该组分C选自双烷基碳酸酯CD和烷基碳酸酯CA的组合。
• [EN] PROCESS FOR THE SYNTHESIS OF N-SUBSTITUTED CYCLIC ALKYLENE UREAS<br/>[FR] PROCÉDÉ POUR LA SYNTHÈSE D'ALKYLÈNE-URÉES N-SUBSTITUÉES CYCLIQUES
  申请人：CYTEC TECH CORP

  公开号：WO2013012995A1

  公开（公告）日：2013-01-24

  The invention relates to a process for the synthesis of N-substituted cyclic alkylene ureas by reacting a multifunctional aliphatic amine A having at least two amino groups which may be primary or secondary, at least one of which is a primary amino group, -NH2, and at least one of which is a secondary amino group, >NH, the other hydrogen group whereof having been substituted by a hydrocarbyl group which in turn may be substituted by a hydroxyl group, or an amino group, or a carboxyl group, or a ketone carbonyl group, or a hydrazide or hydrazone group, or a mercaptan group, and at least one further functional group selected from the group consisting of primary or secondary amino groups and hydroxyl groups, and an aliphatic organic carbonate component C selected from the group consisting of dialkyl carbonates CD and of alkylene carbonates CA.

  本发明涉及一种合成N-取代的环烷基脲的方法，包括将至少具有两个氨基团的多功能脂肪族胺A进行反应，其中至少一个是一级氨基团-NH2，至少一个是二级氨基团->NH，其它氢原子已被烃基取代，该烃基又可以被羟基、氨基、羧基、酮羰基、肼或肼酮基、巯基取代，同时还具有来自于一级或二级氨基团和羟基团的至少一个进一步的功能团，以及从二烷基碳酸酯CD和烷基碳酸酯CA组成的脂肪族有机碳酸酯组分C进行反应。
• [EN] PROCESS FOR CONVERTING CYCLIC ALKYLENE UREAS INTO THEIR CORRESPONDING ALKYLENE AMINES<br/>[FR] PROCÉDÉ DE CONVERSION D'ALKYLÈNE-URÉES CYCLIQUES EN LEURS ALKYLÈNE-AMINES CORRESPONDANTES
  申请人：AKZO NOBEL CHEMICALS INT BV

  公开号：WO2019030196A1

  公开（公告）日：2019-02-14

  The invention relates to a process for converting one or more cyclic ethylene ureas into corresponding ethylene amines and carbon dioxide. In the process, water is contacted with one or more cyclic alkylene urea compounds comprising one or more cyclic alkylene urea moieties in a reaction vessel at a temperature of 150 to 400°C, optionally in the presence of an amine compound selected from the group of primary amines, cyclic secondary amines and bicyclic tertiary amines. The mole ratio of water to cyclic alkylene urea moieties is in the range of from 0.1 to 20. In the reaction, at least a portion of the cyclic alkylene urea moieties are converted to corresponding alkylenediamine moieties and carbon dioxide, and the carbon dioxide is removed from the liquid reaction mixture in a stripping vessel by feeding a stripping fluid to the stripping vessel, and removing a carbon dioxide-containing stripping fluid.

  该发明涉及一种将一个或多个环状乙烯脲转化为相应的乙烯胺和二氧化碳的过程。在该过程中，将水与一个或多个含有一个或多个环状烷基脲基团的环状烯烃脲化合物在反应容器中接触，温度为150至400°C，可选地在存在选择自一级胺、环状二级胺和双环三级胺组的胺化合物的情况下。水与环状烷基脲基团的摩尔比在0.1至20的范围内。在反应中，至少部分环状烷基脲基团被转化为相应的烯二胺基团和二氧化碳，二氧化碳通过向脱除器提供脱除流体，并移除含有二氧化碳的脱除流体从液体反应混合物中去除。