DUTETA | 24368-15-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: DUTETA
• 英文别名: 1,1'-(1,2-ethanediyl)di(2-imidazolidinone)；2-Imidazolidinone, 1,1'-(1,2-ethanediyl)bis-；1-[2-(2-oxoimidazolidin-1-yl)ethyl]imidazolidin-2-one
• CAS: 24368-15-8
• 化学式: C₈H₁₄N₄O₂
• 分子量: 198.225
• InChiKey: RVUHUHUXQMCLGN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.6
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  64.7
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  DUTETA 在 水 、 potassium hydroxide 作用下， 反应 3.0h， 生成 三乙烯四胺
  参考文献：
  名称：

  [EN] PROCESS TO CONVERT CYCLIC ALKYLENE UREAS INTO THEIR CORRESPONDING ALKYLENE AMINES
  [FR] PROCÉDÉ DE CONVERSION D'ALKYLÈNE-URÉES CYCLIQUES EN LEURS ALKYLÈNE-AMINES CORRESPONDANTS

  摘要：

  本发明涉及一种将环状烷基脲转化为相应的烷基胺的过程，其中该过程通过与胺化合物反应来执行，并且该胺化合物包括一级胺、环状二级胺或三级双环胺。

  公开号：

  WO2017137529A1
• 作为产物：
  描述：

  三乙烯四胺 、 alkaline earth salt of/the/ methylsulfuric acid 在 甲醇 、 sulfur 作用下， 120.0 ℃ 、490.29 kPa 条件下， 生成 DUTETA
  参考文献：
  名称：

  Ureas

  摘要：

  公开号：

  US02874149A1

文献信息

• [EN] PROCESS FOR MANUFACTURING A MIXTURE OF STRAIGHT-CHAIN AND NON-STRAIGHT-CHAIN ETHYLENEAMINES<br/>[FR] PROCÉDÉ DE FABRICATION D'UN MÉLANGE D'ÉTHYLÈNEAMINES À CHAÎNES LINÉAIRES ET À CHAÎNES NON LINÉAIRES
  申请人：AKZO NOBEL CHEMICALS INT BV

  公开号：WO2019011709A1

  公开（公告）日：2019-01-17

  The invention pertains to a process for manufacturing a mixture of straight-chain higher ethyleneamines and non-straight-chain higher ethyleneamines selected from branched higher ethyleneamines and cyclic higher ethyleneamines, or the urea derivatives thereof, comprising the step of reacting amine-functional compound with ethanolamine-functional compound in the presence of a carbon oxide delivering agent, wherein a) amine-functional compound comprising a combination of straight-chain amine- functional compound and non-straight-chain amine-functional compound is reacted with straight-chain ethanolamine-functional compound, or b) straight-chain amine-functional compound is reacted with ethanolamine-functional compound comprising a combination of straight-chain ethanolamine-functional compound and non-straight-chain ethanolamine-functional compound, or c) amine-functional compound comprising a combinationof straight-chain amine-functional compound and non-straight-chain amine-functional compound is reacted with ethanolamine-functional compound comprising a combination of straight-chain ethanolamine-functional compound and non-straight-chain ethanolamine-functional compound. It has been found that the process according to the invention makes it possible to prepare tailor-made mixtures of straight-chain and non-straight-chain higher ethyleneamines, or urea derivatives thereof.

  该发明涉及一种用于制造直链高乙烯胺和非直链高乙烯胺的混合物的工艺，所述非直链高乙烯胺选自支链高乙烯胺和环状高乙烯胺，或其尿素衍生物，包括以下步骤：在碳氧化物传递剂的存在下，将胺官能化合物与乙醇胺官能化合物反应，其中a）包括直链胺官能化合物和非直链胺官能化合物的组合的胺官能化合物与直链乙醇胺官能化合物发生反应，或b）直链胺官能化合物与包括直链乙醇胺官能化合物和非直链乙醇胺官能化合物组合的乙醇胺官能化合物发生反应，或c）包括直链胺官能化合物和非直链胺官能化合物组合的胺官能化合物与包括直链乙醇胺官能化合物和非直链乙醇胺官能化合物组合的乙醇胺官能化合物发生反应。据发现，根据本发明的工艺可以制备定制的直链和非直链高乙烯胺的混合物，或其尿素衍生物。
• 1,4,7,10-四氮环十二烷的合成新方法
  申请人：扬州市荣晶工业助剂有限公司

  公开号：CN111808039B

  公开（公告）日：2022-04-26

  本发明提出1,4,7,10‑四氮环十二烷的合成新方法。1,4,7,10‑四氮环十二烷在生物医学和分子学、分子识别、催化、酶化学、超分子化学、储氢材料等主面具有重要用途。本发明以三乙烯四胺和尿素起始原料，先反应生成乙撑双咪唑啉酮（以下简称双咪唑啉酮）；再与1,2‑二卤代乙烷进行缩合反应，生成1,4‑酮‑7,10‑酮‑1,4,7,10‑四氮环十二烷(以下简称二酮环十二烷)；再水解制得1,4,7,10‑四氮环十二烷。本发明最高以74.97%的总收率得到了气相色谱含量99%以上的产物。本发明具有原子利用率高、反应步骤少、简单易控，收率高等优点，是代表清洁、高效生产的新工艺路线。
• [EN] PROCESS FOR PREPARING CYCLIC ALKYLENE UREAS<br/>[FR] PROCÉDÉ DE PRÉPARATION D'ALKYLÈNE-URÉES CYCLIQUES
  申请人：AKZO NOBEL CHEMICALS INT BV

  公开号：WO2019030195A1

  公开（公告）日：2019-02-14

  A process for producing a cyclic alkylene urea product of Formula I: in which a compound of Formula II and/or Formula III is contacted in a reaction zone with a compound of Formula IV and/or Formula V and in the presence of one or more carbonyl delivering compounds; in which; R1 is –[A−X−]qR3; R2 is on each occurrence independently selected from H and C1 to C6 alkyl groups which are optionally substituted by one or two groups selected from −OH and −NH2; R3 is on each occurrence independently selected from H and C1 to C6 alkyl groups which are optionally substituted by one or two groups selected from −OH and −NH2; A is on each occurrence independently selected from C1 to C3 alkylene units, optionally substituted by one or more C1 to C3 alkyl groups; X is on each occurrence independently selected from −O−, −NR2−, groups of Formula VI, and groups of Formula VII and p and q are each independently selected from a whole number in the range of from 0 to 8; wherein the compound of Formula II and/or the compound of Formula III are added to a reaction zone comprising compound of Formula IV and/or compound of Formula (V) continuously or semi-continuously over a period of time, or in two or more batches.

  一种生产公式I的环烷基脲产物的方法：在反应区中，将公式II和/或公式III的化合物与公式IV和/或公式V的化合物接触，并在一个或多个羰基供体化合物的存在下进行反应；其中，R1是- [A-X-] qR3; R2在每次出现时独立地选择H和C1到C6烷基，其可以被一个或两个从-OH和-NH2中选择的基团取代；R3在每次出现时独立地选择H和C1到C6烷基，其可以被一个或两个从-OH和-NH2中选择的基团取代；A在每次出现时独立地选择C1到C3烷基单元，其可以被一个或多个C1到C3烷基取代；X在每次出现时独立地选择-O-，-NR2-，公式VI的基团和公式VII的基团；p和q各自独立地选择从0到8的整数；其中，将公式II和/或公式III的化合物连续或半连续地在一段时间内加入包含公式IV和/或公式V的化合物的反应区中，或者分成两个或多个批次加入。
• [EN] PROCESS FOR MANUFACTURING A CYCLIC UREA ADDUCT OF AN ETHYLENEAMINE COMPOUND<br/>[FR] PROCÉDÉ DE FABRICATION DE PRODUIT D'ADDITION D'URÉE CYCLIQUE D'UN COMPOSÉ ÉTHYLÈNEAMINE
  申请人：AKZO NOBEL CHEMICALS INT BV

  公开号：WO2019030191A1

  公开（公告）日：2019-02-14

  The invention pertains to a process for manufacturing a cyclic urea adduct of an ethyleneamine compound, the ethyleneamine compound having a linear -NH-CH2-CH2-NH- group, the process comprising the steps of - in an absorption step contacting a liquid medium comprising an ethyleneamine compound having a linear -NH-CH2-CH2-NH- group with a CO2-containing gas stream at a pressure of 1 -20 bara, resulting in the formation of a liquid medium into which CO2 has been absorbed, - bringing the liquid medium to cyclic urea formation conditions, and in an urea formation step forming cyclic urea adduct of the ethyleneamine compound, urea formation conditions including a temperature of at least 120°C, wherein the total pressure at the end of the urea formation step is at most 20 bara, wherein the temperature in the absorption step is lower than the temperature in the urea formation step. It has been found that the process according to the invention makes it possible to obtain cyclic urea adducts in an efficient manner in the absence of metal-containing catalysts and to perform the process under relatively mild conditions, in particular relatively low pressure. More specifically, by separating the CO2 absorption step from the urea formation step, the CO2 absorption step can be carried out at relatively low temperatures and pressures. And because the CO2 is already present in the system at the beginning of the urea formation step, the pressure in the urea formation step does not need to be high.

  该发明涉及一种制造具有线性-NH-CH2-CH2-NH-基团的乙二胺化合物的环式脲加合物的工艺，该工艺包括以下步骤：-在吸收步骤中，将包含具有线性-NH-CH2-CH2-NH-基团的乙二胺化合物的液体介质与含CO2气流在1-20 bara的压力下接触，导致形成已吸收CO2的液体介质，-将液体介质带到环式脲形成条件，并在脲形成步骤中形成乙二胺化合物的环式脲加合物，脲形成条件包括至少120°C的温度，在脲形成步骤结束时的总压力最多为20 bara，在吸收步骤中的温度低于脲形成步骤中的温度。发现该发明的工艺使得在无金属催化剂的情况下以相对温和的条件，特别是相对低压下有效地获得环式脲加合物成为可能。更具体地，通过将CO2吸收步骤与脲形成步骤分离，CO2吸收步骤可以在相对低温和压力下进行。由于在脲形成步骤开始时系统中已经存在CO2，因此脲形成步骤中的压力不需要很高。
• Process for the Synthesis of N-substituted Cyclic Alkylene Ureas
  申请人：Cytec Technology Corp.

  公开号：EP2548869A1

  公开（公告）日：2013-01-23

  The invention relates to a process for the synthesis of N-substituted cyclic alkylene ureas by reacting a multifunctional aliphatic amine A having at least two amino groups which may be primary or secondary, at least one of which is a primary amino group, -NH2, and at least one of which is a secondary amino group, >NH, the other hydrogen group whereof having been substituted by a hydrocarbyl group which in turn may be substituted by a hydroxyl group, or an amino group, or a carboxyl group, or a ketone carbonyl group, or a hydrazide or hydrazone group, or a mercaptan group, and at least one further functional group selected from the group consisting of primary or secondary amino groups and hydroxyl groups, and an aliphatic organic carbonate component C selected from the group consisting of dialkyl carbonates CD and of alkylene carbonates CA.

  本发明涉及一种合成N-取代环状烷基脲的方法，该方法通过反应一种具有至少两个氨基的多功能脂肪族胺A来实现，其中至少一个是一级氨基-NH2，至少一个是二级氨基->NH，其它氢原子被烃基取代，该烃基又可以被羟基、氨基、羧基、酮羰基、肼或肼酮基、巯基取代，同时还包括至少一种来自于一级或二级氨基与羟基的功能基团，以及一种来自于脂肪族有机碳酸酯组分C的反应，该组分C选自双烷基碳酸酯CD和烷基碳酸酯CA的组合。