N-2-aminoethyl-N'-(2-N'-methylaminoethyl)-1,2-ethanediamine | 62247-47-6

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-2-aminoethyl-N'-(2-N'-methylaminoethyl)-1,2-ethanediamine
• 英文别名: N'-[2-[2-(methylamino)ethylamino]ethyl]ethane-1,2-diamine
• CAS: 62247-47-6
• 化学式: C₇H₂₀N₄
• 分子量: 160.263
• InChiKey: VELRFBWXSQBZEM-UHFFFAOYSA-N

物化性质

• 沸点：
  267.3±8.0 °C(Predicted)
• 密度：
  0.919±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -2
• 重原子数：
  11
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  62.1
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1,3-Bis-cyanomethyl-imidazolin 在 Ra-Co 氢气 作用下， 以 2-甲基四氢呋喃 、 二乙二醇二甲醚 为溶剂， 120.0 ℃ 、10.0 MPa 条件下， 反应 3.0h， 生成 N-2-aminoethyl-N-methyl-N'-2-aminoethyl-1,2-ethanediamine 、 N-2-aminoethyl-N'-(2-N'-methylaminoethyl)-1,2-ethanediamine 、 三乙烯四胺
  参考文献：
  名称：

  METHYL-SUBSTITUTED TETA COMPOUNDS

  摘要：

  该发明涉及一种制备至少含有一个甲基基团（Me-TETA或甲基取代的TETA化合物）的三乙烯四胺的过程。Me-TETA是通过在催化剂存在下氢化双氰甲基咪唑啉（BCMI）而制备的。本发明还涉及甲基取代的TETA化合物本身。本发明还涉及将甲基取代的TETA化合物用作反应物或中间体，例如在生产涂料或胶粘剂中的用途。

  公开号：

  US20120101303A1

文献信息

• [EN] COMPOUNDS<br/>[FR] COMPOSÉS
  申请人：XENTION LTD

  公开号：WO2010139953A1

  公开（公告）日：2010-12-09

  A compound of formula (I): or its salts or pharmaceutically acceptable derivatives thereof wherein; A represents a chemical moiety with the general formula (II): X is selected from a group consisting of CH2, C(=O), CH(R5), C(R5)(R6) or C(R5)(R6)CH2; R1 is selected from the group consisting of optionally substituted arylalkyl, and optionally substituted heteroarylalkyl; R2 is selected from the group consisting of optionally substituted aryl or optionally substituted heteroaryl or NR7R8; R3 is selected from the group consisting of hydrogen, halogen, hydroxyl, alkoxy, aryloxy, optionally substituted alkyl, optionally substituted amino, optionally substituted amino sulfonyl or nitrile; R4 is selected from the group consisting of hydrogen, optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted heterocycloalkyl, optionally substituted acyl, optionally substituted sulfonyl, optionally substituted sulfamoyl, optionally substituted aryl, optionally substituted arylalkyl, and optionally substituted heteroaryl; R5 and R6 for each occurrence is optionally substituted alkyl; R7 and R8 are the same or different and each represents hydrogen, optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted arylalkyl, optionally substituted aryl or optionally substituted heteroaryl; n = 1 or 2 is provided. Pharmaceutical compositions comprising the compounds are also provided. The compounds are useful in treating various conditions including arrhythmia.

  化合物的结构式（I）：或其盐或药学上可接受的衍生物，其中；A代表具有一般式（II）的化学基团：X选自由CH2、C（=O）、CH（R5）、C（R5）（R6）或C（R5）（R6）CH2组成的群；R1选自可选择的取代芳基烷基和可选择的取代杂环芳基烷基组成的群；R2选自可选择的取代芳基或可选择的取代杂环芳基或NR7R8组成的群；R3选自氢、卤素、羟基、烷氧基、芳氧基、可选择的取代烷基、可选择的取代氨基、可选择的取代氨基磺酰基或腈组成的群；R4选自氢、可选择的取代烷基、可选择的取代环烷基、可选择的取代杂环烷基、可选择的取代酰基、可选择的取代磺酰基、可选择的取代磺胺基、可选择的取代芳基、可选择的取代芳基烷基和可选择的取代杂环芳基组成的群；R5和R6每次出现时均为可选择的取代烷基；R7和R8相同或不同，每个代表氢、可选择的取代烷基、可选择的取代环烷基、可选择的取代芳基烷基、可选择的取代芳基或可选择的取代杂环芳基；n = 1或2。还提供了包含该化合物的药物组合物。这些化合物在治疗各种疾病，包括心律失常方面具有用途。
• DERIVATIVES OF XANTHONE COMPOUNDS
  申请人：Zou Hanxun

  公开号：US20140349918A1

  公开（公告）日：2014-11-27

  The present invention relates to xanthone analogs. Such compounds may be used in the treatment of bacterial infections.

  本发明涉及黄酮类似物。这些化合物可用于治疗细菌感染。
• CARBONATE DERIVATIVE PRODUCTION METHOD
  申请人：NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY

  公开号：US20200079723A1

  公开（公告）日：2020-03-12

  The objective of the present invention is to provide a method for producing a carbonate derivative in a safe and efficient manner. The method for producing a carbonate derivative according to the present invention is characterized in comprising irradiating light on a composition containing a C 1-4 halogenated hydrocarbon having one or more kinds of halogen atoms selected from the group consisting of a chlorine atom, a bromine atom and an iodine atom, a nucleophilic functional group-containing compound and the specific base in the presence of oxygen.

  本发明的目的是以安全高效的方式提供生产碳酸酯衍生物的方法。根据本发明的生产碳酸酯衍生物的方法的特征在于，在含有一种或多种来自氯原子、溴原子和碘原子组成的卤素原子的C1-4卤代烃、含有亲核功能基团的化合物和特定碱的组合物中，在氧气存在下照射光线。
• RHODAMINE-BASED COLORING COMPOSITION
  申请人：WAKO PURE CHEMICAL INDUSTRIES, LTD.

  公开号：US20170145216A1

  公开（公告）日：2017-05-25

  A colored resin composition using a conventional rhodamine derivative has not provided heat resistance in a practical range. Therefore, it is an object of the present invention to provide a coloring composition having higher heat resistance as compared with the conventional coloring composition. The present invention relates to a compound represented by the following general formula (1), and a polymer having a monomer unit derived from the compound, and the like. (wherein R 1 to R 4 each independently represent a hydrogen atom, an alkyl group, and the like; R 7 represents a hydrogen atom or a methyl group; R 8 and R 9 each independently represent a hydrogen atom or an alkyl group; Y represents a nitrogen atom or a group represented by the following formula (1-1): A 1 represents an alkylene group which has at least one group selected from —O—, —OCO—, —COO—, —NHCO—, —CONH—, —NHCONH— and an arylene group in the chain, and the like; A 2 represents —NH— or —O—; An − represents an anion containing an aryl group having an electron-withdrawing substituent, and the like; n represents an integer of 0 to 3; R 8 and R 9 may form a cyclic structure of a 5 to 6 membered ring together with —N—(CH 2 ) n —Y— bonding thereto.)

  使用传统的罗丹明衍生物的有色树脂组合物在实际范围内未提供耐热性。因此，本发明的目的是提供一种比传统着色组合物具有更高耐热性的着色组合物。本发明涉及由以下通式（1）所代表的化合物，以及具有源自该化合物的单体单位的聚合物等。（其中R1至R4分别独立地代表氢原子、烷基基团等；R7代表氢原子或甲基基团；R8和R9分别独立地代表氢原子或烷基基团；Y代表氮原子或由以下式（1-1）所代表的基团：A1代表在链中至少具有一种从—O—，—OCO—，—COO—，—NHCO—，—CONH—，—NHCONH—和芳基基团中选择的基团的亚烷基基团等；A2代表—NH—或—O—；An−代表含有具有电子吸引取代基的芳基团的阴离子等；n表示0至3的整数；R8和R9可以与结合其的—N—（CH2）n—Y—共同形成5至6元环的环状结构。）
• PHENALENE-1-ONE DERIVATIVES, METHOD FOR PRODUCING SAME AND USE THEREOF
  申请人：Bäumler Wolfgang

  公开号：US20140039184A1

  公开（公告）日：2014-02-06

  The present disclosure relates to a compound of formula (1): where R1 through R8, which can be identical or different from each other, each are selected from of the group comprising hydrogen and the radical —(CH 2 ) k —X, where k is a whole number from 1 to 20 and where X is an organic radical comprising a) at least one neutral, protonizable nitrogen atom and/or b) at least one positively charged nitrogen atom, under the provision that at least 1 radical R1 through R8 is not hydrogen. The invention further relates to the production and use of said compound.

  本公开涉及一种化合物，其化学式为(1)：其中R1至R8，可以相同也可以不同，每个都选自包括氢和基团—(CH2)k—X的群体，其中k是1到20的整数，X是一个有机基团，包括a)至少一个中性、可质子化的氮原子和/或b)至少一个带正电荷的氮原子，前提是至少有一个基团R1至R8不是氢。本发明还涉及所述化合物的生产和使用。