benzaldehyde (E)-N-benzenesulfenylimine | 53075-84-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: benzaldehyde (E)-N-benzenesulfenylimine
• 英文别名: (E)-1-phenyl-N-phenylsulfanylmethanimine
• CAS: 53075-84-6
• 化学式: C₁₃H₁₁NS
• 分子量: 213.303
• InChiKey: ZKNRVOCALMUANN-SDNWHVSQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  37.7
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  benzaldehyde (E)-N-benzenesulfenylimine 在 4-二甲氨基吡啶 、 (+)-N-(phenylsulfonyl)(3,3-dichlorocamphoryl)oxaziridine 、 三乙胺 、 三氟乙酸 、 lithium diisopropyl amide 作用下， 以 四氯化碳 为溶剂， 反应 12.0h， 生成 (R)-3-benzamido-3-phenylpropanoic acid methyl ester
  参考文献：
  名称：

  Asymmetric synthesis of sulfinimines: applications to the synthesis of nonracemic .beta.-amino acids and .alpha.-hydroxyl .beta.-amino acids

  摘要：

  Asymmetric oxidation of sulfenimines 1 affords sulfinimines 2 (88-90% ee) which are chiral ammonia imine synthons useful in the enantioselective synthesis of beta-amino acids and alpha-hydroxy-beta-amino acids such as the C-13 side chain of taxol (2R,3S)-7.

  DOI：

  10.1021/jo00050a007
• 作为产物：
  描述：

  α-Azidobenzyl Phenyl Sulfide 以50%的产率得到
  参考文献：
  名称：

  JARVIS B. B.; NICHOLAS P. E.; MIDIWO J. O., J. AMER. CHEM. SOC., 1981, 103, NO 13, 3878-3882

  摘要：

  DOI：

文献信息

• Enantioselective synthesis of optically active homoallylamines by nucleophilic addition of chirally modified allylboranes to N-silylimines
  作者：Shinichi Itsuno、Katsuhiro Watanabe、Takeshi Matsumoto、Shizue Kuroda、Ayako Yokoi、Ashraf El-Shehawy

  DOI：10.1039/a902635e

  日期：——

  Enantioselectivity in the allylboration of N-silylimines with a variety of chirally modified allylboron reagents has been examined. Optically active N-sulfonylamino alcohols (16, 17 and 19) derived from D-camphor and norephedrine were found to be efficient chiral ligands for the allylboration reagent. These reagents smoothly reacted with N-silylimines to give the corresponding homoallylic amines in

  已经研究了N-甲硅烷基丙胺与多种手性改性的烯丙基硼试剂在烯丙基硼化中的对映选择性。发现衍生自D-樟脑和去氧麻黄碱的旋光性N-磺酰基氨基醇（16、17和19）是烯丙基硼化试剂的有效手性配体。这些试剂与N-甲硅烷基亚胺平滑反应，以高达96％ee的高对映体选择性得到相应的均烯丙基胺。
• Asymmetric Synthesis and Properties of Sulfinimines (Thiooxime <i>S</i>-Oxides)
  作者：Franklin A. Davis、Rajarathnam E. Reddy、Joanna M. Szewczyk、G. Venkat Reddy、Padma S. Portonovo、Huiming Zhang、Dean Fanelli、R. Thimma Reddy,、Ping Zhou、Patrick J. Carroll

  DOI：10.1021/jo970077e

  日期：1997.4.1

  Enantiomerically pure sulfinimines (thiooxime S-oxides 10), important building blocks in the asymmetric synthesis of amine derivatives, are prepared in good to excellent yields in one step from aromatic, heteroaromatic, and aliphatic aldehydes. This protocol involves treating commercially available (R)- or (S)-menthyl p-toluenesufinate (Andersen reagent 4) with LiHMDS, followed by the aldehyde, affording

  对映体纯的亚砜亚胺（硫肟肟S-氧化物10），是胺衍生物不对称合成的重要组成部分，一步一步从芳族，杂芳族和脂族醛制备，收率良好至优异。该方案涉及先用LiHMDS处理醛对苯甲酸酯的（R）-或（S）-薄荷基对甲苯磺酸酯（Andersen试剂4），然后用醛处理，仅得到（E）-10。亚磺胺10是通过甲硅烷基亚磺酰胺阴离子13与醛的Peterson型烯化反应形成的。通过四氧化三锂（12a）与双（三甲基甲硅烷基）亚磺酰胺11的反应生成阴离子13，双（三甲基甲硅烷基）亚磺酰胺11在4与LiHMDS的反应中形成。形成的另一产物是O-（三甲基甲硅烷基）薄荷醇（12c），将其以> 80％的产率分离出来以进行再循环。
• The use of N-sulfenylimines in the β-lactam synthon method: Staudinger reaction, oxidation of the cycloadducts and ring opening of β-lactams
  作者：Stéphanie Coantic、Dominique Mouysset、Serge Mignani、Michel Tabart、Lucien Stella

  DOI：10.1016/j.tet.2007.01.051

  日期：2007.4

  Selected N-sulfenylimines act as good nucleophilic partners in the Staudinger reaction with methoxy- and benzyloxy-ketenes. The choice of diisopropylethylamine as a non-nucleophilic Lewis base for the generation of ketenes from acid chlorides is a determining factor for the success of the reaction. N-Sulfenyl-β-lactams are obtained in good to excellent yields and with moderate cis/trans diastereoselectivity

  所选的N-亚硫基亚胺在Staudinger与甲氧基和苄氧基-乙烯酮反应中充当良好的亲核伴侣。选择二异丙基乙胺作为非亲核的路易斯碱，用于从酰氯生成烯酮是反应成功的决定因素。N-亚磺酰基-β-内酰胺以良好至优异的产率获得，并且具有适度的顺/反非对映选择性。然后，通过调节硫原子的氧化态，将它们定量和选择性地转化为N-亚磺酰基-或N-磺酰基-β-内酰胺。氧化过程导致氮原子取代基的极性反转，并随后通过N的反应使开环平滑-硫醇化的β-内酰胺类具有各种亲核试剂。整个序列为获得高度官能化的β-氨基酸衍生物提供了直接而有效的途径。
• Hydrogenated modified polymer, process for producing the same and composition containing the same
  申请人：JSR Corporation

  公开号：US20030100683A1

  公开（公告）日：2003-05-29

  An objective of the present invention is to provide a hydrogenated modified polymer which can afford a molded body excellent in improvement in the balance among the impact resistance, the strength, the adherability and as the appearance, and a process for producing the same as well as a composition containing the same. Another objective is to provide a composition which can afford a molded body excellent in the balance among the flame retardancy, the tensile strength, the tensile extension, the heat resistance, the characteristic at low temperature, the insulation property, the pliability and the like. The hydrogenated modified polymer of the invention is a hydrogenated polymer of a modified conjugated diene-based polymer obtained by reacting an alkoxysilane compound to a polymer which is polymerized a conjugated diene or a conjugated diene and another monomer using an organic alkali metal compound as a polymerization initiator in an inert organic solvent such as cyclohexane and the like. The hydrogenated modified polymer composition of the invention contains the above-mentioned hydrogenated modified polymer and at least one selected from the group consisting of nonpolar polymer, polar polymer and filler.

  本发明的目标是提供一种氢化改性聚合物，该聚合物能够提供在冲击抗性、强度、附着性和外观之间平衡改善的模塑体，以及生产该聚合物的方法和包含该聚合物的组合物。另一个目标是提供一种组合物，该组合物能够提供在阻燃性、拉伸强度、拉伸延伸、耐热性、低温特性、绝缘性、可塑性等方面平衡改善的模塑体。本发明的氢化改性聚合物是一种氢化的改性共轭二烯基聚合物，通过在惰性有机溶剂如环己烷等中使用有机金属碱作为聚合引发剂，将烯丙基二烯或烯丙基二烯和另一种单体聚合而成的聚合物中反应烷氧基硅烷化合物而得到。本发明的氢化改性聚合物组合物包含上述氢化改性聚合物和至少选自非极性聚合物、极性聚合物和填料的一种。
• TERMINAL-MODIFIED BLOCK COPOLYMER AND COMPOSITION CONTAINING SAID COPOLYMER
  申请人：Asahi Kasei Kogyo Kabushiki Kaisha

  公开号：EP0245505A1

  公开（公告）日：1987-11-19

  A terminal-modified block copolymer wherein an amino group- or amino group-containing, terminal-treating agent is bound to the terminals of the polymer. It is obtained by reacting the active terminals of a block copolymer of a conjugated diene with a vinylaromatic hydrocarbon comprising 5 to 95 % of a vinylaromatic hydrocarbon and having a number- average molecular weight of 5,000 to 1,000,000 (obtained by using at least one member selected from among alkali metals and organic alkali metal compounds as a polymerization initiator) with at least one terminal-treating agent selected from among imide compounds, cyanamide compounds, aziridinyl compounds, amide compounds, and other tertiary amino group-containing compounds. A pressure-sensitive adhesive composition excellent in adhesiveness and anti-creeping properties comprising said block copolymer and a tackifying resin, a water-absorbing composition comprising said block copolymer and a highly water-absorbing resin, a thermoplastic resin composition comprising said block copolymer and a thermoplastic resin, and a conductive composition comprising said block copolymer and a conductive material are also disclosed.

  一种末端改性嵌段共聚物，其中一种含氨基或氨基基团的末端处理剂与聚合物的末端结合。它是通过将共轭二烯与乙烯基芳烃的嵌段共聚物的活性末端与至少一种末端处理剂反应而得到的，该末端处理剂选自亚胺化合物、氰胺化合物、氮杂环丁基化合物、酰胺化合物和其他含三级氨基基团的化合物，乙烯基芳烃的含量为 5%至 95%，平均分子量为 5,000 至 1,000,000 （通过使用至少一种选自碱金属和有机碱金属化合物的成员作为聚合引发剂而得到）。此外，还公开了由所述嵌段共聚物和增粘树脂组成的粘合性和防蠕变性能优异的压敏胶组合物、由所述嵌段共聚物和高吸水性树脂组成的吸水组合物、由所述嵌段共聚物和热塑性树脂组成的热塑性树脂组合物以及由所述嵌段共聚物和导电材料组成的导电组合物。