S-acetyl-(1-allyloxy-3-mercapto-2-hydroxypropane) | 151493-87-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 硫代羧酸及其衍生物
• 英文名称: S-acetyl-(1-allyloxy-3-mercapto-2-hydroxypropane)
• 英文别名: S-(2-hydroxy-3-prop-2-enoxypropyl) ethanethioate
• CAS: 151493-87-7
• 化学式: C₈H₁₄O₃S
• 分子量: 190.263
• InChiKey: VAYPQOGEJDZHCQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  71.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  S-acetyl-(1-allyloxy-3-mercapto-2-hydroxypropane) 在 三乙胺 作用下， 以 氯仿 为溶剂， 反应 2.0h， 以97%的产率得到(1-Prop-2-enoxy-3-sulfanylpropan-2-yl) acetate
  参考文献：
  名称：

  Novel triethylamine catalyzed S → O acetyl migration reaction to generate candidate thiols for construction of topological and functional sulfur-containing polymers

  摘要：

  各种含硫单体及由不同环氧化合物转化而来的聚合物材料。

  DOI：

  10.1039/c4ra09842k
• 作为产物：
  描述：

  烯丙基缩水甘油醚 、 硫代乙酸 以 水 为溶剂， 反应 10.0h， 以100%的产率得到S-acetyl-(1-allyloxy-3-mercapto-2-hydroxypropane)
  参考文献：
  名称：

  水中含硫代酸的环氧乙烷的无催化剂有效区域选择性开环

  摘要：

  摘要 在无催化剂条件下，在水存在下研究了硫代乙酸和硫代苯甲酸的环氧化物开环。这种绿色和简单的过程产生了极好的产量。通过简单的滗析，获得高纯度和大规模的产品。在这个过程中，没有观察到烷基卤和酯裂解。

  DOI：

  10.1080/00397911.2010.491172

文献信息

• CHROMATOGRAPHY MEMBRANES, DEVICES CONTAINING THEM, AND METHODS OF USE THEREOF
  申请人：Brellisford Damian

  公开号：US20170145053A1

  公开（公告）日：2017-05-25

  Described herein are fluid treatment devices for use in tangential flow filtration, comprising a housing unit and a composite material, wherein the composite material comprises: a support member comprising a plurality of pores extending through the support member; and a non-self-supporting macroporous cross-linked gel comprising macropores having an average size of 10 nm to 3000 nm, said macroporous gel being located in the pores of the support member. The invention also relates to a method of separating a substance from a fluid, comprising the step of placing the fluid in contact with an inventive device, thereby adsorbing or absorbing the substance to the composite material contained therein.

  本文描述了用于切向流过滤的流体处理装置，包括一个外壳单元和一个复合材料，其中复合材料包括：支撑成员，其包括穿过支撑成员的多个孔;以及非自支撑的大孔交联凝胶，其具有平均尺寸为10纳米至3000纳米的大孔，所述大孔凝胶位于支撑成员的孔中。本发明还涉及一种从流体中分离物质的方法，包括将流体与本发明的装置接触，从而将物质吸附或吸收到其中所含的复合材料中。
• Latent thiol monomers
  申请人：ROHM AND HAAS COMPANY

  公开号：EP0542438A1

  公开（公告）日：1993-05-19

  Latent thiol monomers and their use in the synthesis of polymers and graft copolymers are described. The latent thiol monomers comprise at least one polymerizable functional group and at least one protected thiol group. The polymers or copolymers may be used in adhesive, caulk, or mastic compositions. The copolymer may also be used as a compatiblizer for physical blends of at least two polymers.

  本文介绍了潜伏硫醇单体及其在聚合物和接枝共聚物合成中的应用。潜伏硫醇单体包括至少一个可聚合官能团和至少一个受保护的硫醇基团。聚合物或共聚物可用于粘合剂、填缝剂或胶泥组合物。共聚物还可用作至少两种聚合物的物理混合物的相容剂。
• Chromatography membranes, devices containing them, and methods of use thereof
  申请人：Natrix Separations, Inc.

  公开号：US10800808B2

  公开（公告）日：2020-10-13

  Described herein are fluid treatment devices for use in tangential flow filtration, comprising a housing unit and a composite material, wherein the composite material comprises: a support member comprising a plurality of pores extending through the support member; and a non-self-supporting macroporous cross-linked gel comprising macropores having an average size of 10 nm to 3000 nm, said macroporous gel being located in the pores of the support member. The invention also relates to a method of separating a substance from a fluid, comprising the step of placing the fluid in contact with an inventive device, thereby adsorbing or absorbing the substance to the composite material contained therein.

  本发明描述了用于切向流过滤的流体处理装置，该装置包括外壳单元和复合材料，其中复合材料包括：支撑件，该支撑件包括多个延伸穿过支撑件的孔隙；以及非自支撑的大孔交联凝胶，该凝胶包括平均尺寸为 10 nm 至 3000 nm 的大孔，所述大孔凝胶位于支撑件的孔隙中。本发明还涉及一种从流体中分离物质的方法，包括将流体与本发明装置接触，从而将物质吸附或吸收到其中所含的复合材料上的步骤。
• One-Pot Tandem Synthesis of <font>β</font>-Trimethylsilyloxy Thioesters from Thioacids, Epoxides, and HMDS Catalyzed by Silica Gel Under Solvent-Free Conditions
  作者：Mohammad Abbasi

  DOI：10.1080/00397911.2012.667183

  日期：2013.7.3

  A procedure for one-pot preparation of beta-trimethylsilyloxy thioesters from epoxides, thioacids, and hexamethyl disilazane (HMDS) in the presence of silica gel under solvent-free condition was developed. The desired silylated products were isolated in good to excellent yields after silica-gel column chromatography.Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) to view the free supplemental file.
• Monolithic Neat Graphene Oxide Aerogel for Efficient Catalysis of S → O Acetyl Migration
  作者：Li Peng、Yaochen Zheng、Jiachen Li、Yu Jin、Chao Gao

  DOI：10.1021/acscatal.5b00233

  日期：2015.6.5

  Graphene oxide (GO) is highly attractive for catalysis because of its large specific surface area and rich chemical structures. However, it has generally been used as a catalyst carrier. Here, we designed a three-dimensional monolith of neat GO aerogel as a fixed bed carbocatalyst used in the reaction of S -> O acetyl migration for the synthesis of thiol compounds, showing the merits of ultrafast catalytic speed (5-8 h), high selectivity (100%), high yields (near 100%), easy isolation of products, and long -life recyclability (>18 times). Particularly, we achieved for the first time thiol compounds containing functional groups of halogen and hydroxyl, which cannot be synthesized using other currently reported catalysts Control experiments demonstrated that the efficient catalysis mechanism is mainly attributed to the protonic functional groups, ultralarge size, and unpaired electrons of GO, as well as the "cage effect" at nanoscale confined spaces of aerogel cells