tris(2,4,6-trimethylphenyl)bismuth | 59344-64-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: tris(2,4,6-trimethylphenyl)bismuth
• 英文别名: trimesitylbismuthane
• CAS: 59344-64-8
• 化学式: C₂₇H₃₃Bi
• 分子量: 566.539
• InChiKey: BNECSQBRUJYXAU-UHFFFAOYSA-N

物化性质

• 熔点：
  136-137 °C

计算性质

• 辛醇/水分配系数(LogP)：
  4.98
• 重原子数：
  28
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  tris(2,4,6-trimethylphenyl)bismuth 在 Na 作用下， 以 乙醚 、 氨 为溶剂， 生成 tetrakis(2,4,6-trimethylphenyl)dibismuthoxide
  参考文献：
  名称：

  Synthesis and crystal structure of tetrakis(2,4,6-trimethylphenyl)dibismuthoxide

  摘要：

  Bis(2,4,6-trimethylphenyl)chlorobismuth (1), synthesized by comproportionation reaction of tris(2,4,6-trimethylphenyl)bismuth and bismuth chloride, was reduced with sodium in liquid ammonia. By subsequent insertion of oxygen into the Bi-Bi bond of the intermediate dimer tetrakis(2,4,6,-trimethylphenyl)dibismuth the title compound (2) was formed whose crystal structure has been determined: [monoclinic, space group P2(1)/n; a = 12.225(1) Angstrom; b = 14.957(1) Angstrom; c = 18.531(1) Angstrom; beta = 97.76(1)degrees; Z = 4]. (2) shows a Bi-O-Bi bond angle of 124.6 degrees and a short intramolecular nonbonding Bi ... Bi distance of 3.665 Angstrom, probably the inherent reason for the metallic colour of (2). (C) 1998 Elsevier Science S.A. All rights reserved.

  DOI：

  10.1016/s0022-328x(98)00482-3
• 作为产物：
  描述：

  氯化铋 以 四氢呋喃 为溶剂， 生成 tris(2,4,6-trimethylphenyl)bismuth
  参考文献：
  名称：

  Palladium(II)-Catalyzed Aryl Coupling of Triarylbismuthines under Air

  摘要：

  三芳基铋烷在空气中与催化量的醋酸钯(II)在甲醇中迅速反应，生成相应的双芳烃，产率很高。氧的存在对这种催化偶联反应是不可或缺的，因为在氮气环境下双芳烃的形成相当缓慢。在反应过程中观察到了氧的吸收，另外制备的钯-氧复合物即使在惰性气体下也能有效作为该偶联反应的试剂。

  DOI：

  10.1246/bcsj.72.1851

文献信息

• Activity of Antifungal Organobismuth(III) Compounds Derived from Alkyl Aryl Ketones against S. cerevisiae: Comparison with a Heterocyclic Bismuth Scaffold Consisting of a Diphenyl Sulfone
  作者：Toshihiro Murafuji、Mai Tomura、Katsuya Ishiguro、Isamu Miyakawa

  DOI：10.3390/molecules190811077

  日期：——

  A series of hypervalent organobismuth(III) compounds derived from alkyl aryl ketones [XBi(5-R'C6H3-2-COR)(Ar)] was synthesized to investigate the effect of the compounds' structural features on their antifungal activity against the yeast Saccharomyces cerevisiae. In contrast to bismuth heterocycles [XBi(5-RC6H3-2-SO2C6H4-1'-)] derived from diphenyl sulfones, a systematic quantitative structure-activity

  合成了一系列衍生自烷基芳基酮 [XBi(5-R'C6H3-2-COR)(Ar)] 的高价有机铋 (III) 化合物，以研究这些化合物的结构特征对其抗酵母菌活性的影响酿酒酵母。与衍生自二苯砜的铋杂环 [XBi(5-RC6H3-2-SO2C6H4-1'-)] 相比，系统的定量构效关系研究是可能的。活性取决于 Ar 基团，对于较重的 X 原子会增加，而延长烷基链 (R) 或引入取代基 (R') 会降低活性。IBi(C6H4-2-COCH3)(4-FC6H4) 是最活跃的。其活性优于相关的无环类似物 ClBi[C6H4-2-CH2N(CH3)2](Ar) 和 ClBi(C6H4-2-SO2 tert-Bu)(Ar)，也可与杂环 ClBi( C6H4-2-SO2C6H4-1'-)，这是我们之前研究中最活跃的化合物。密度函数理论计算表明，高价铋烷与铋原子上的生物分子发生亲核加成，得到中间体 ate 络
• Synthesis of 2-Aryl-3-(arylselanyl)imidazo[1,2-a]pyridines: Copper­-Catalyzed One-Pot, Two-Step Se-Arylation of Selenium with Imidazopyridines and Triarylbismuthanes
  作者：Mio Matsumura、Shuji Yasuike、Kaito Kondo、Keiko Kanasaki、Yuki Murata、Naoki Kakusawa

  DOI：10.1055/s-0036-1591972

  日期：2018.6

  donors containing elements such as boron, silicon, tin, and iodine. A simple and general method for the synthesis of 2-aryl-3-(arylselanyl)imidazo[1,2-a]pyridines is described. A one-pot, two-step reaction between triarylbismuthanes and diimidazopyridyl diselenides, generated from imidazo[1,2-a]pyridines and Se powder in the presence of CuI and 1,10-phenanthroline, affords 3-selanylimidazopyridines in moderate

  摘要 描述了一种简单且通用的合成2-芳基-3-（芳基硒基）咪唑并[1,2- a ]吡啶的方法。在CuI和1,10-菲咯啉的存在下，由咪唑并[1,2- a ]吡啶和Se粉末生成的三芳基双muthanes与二咪唑并吡啶基二硒化物之间的一锅两步反应，可提供中等收率至优异收率的3-selanylimidazopyridines。在有氧条件下。反应有效地进行，并且铋上的硒和所有芳基转移到偶联产物上。与其他含有硼，硅，锡和碘等元素的芳基供体相比，三芳基双muthanes可获得更好的结果。 描述了一种简单且通用的合成2-芳基-3-（芳基硒基）咪唑并[1,2- a ]吡啶的方法。在CuI和1,10-菲咯啉的存在下，由咪唑并[1,2- a ]吡啶和Se粉末生成的三芳基双muthanes与二咪唑并吡啶基二硒化物之间的一锅两步反应，可提供中等收率至优异收率的3-selanylimidazopyridines。在
• Non-cluster type bismuth compounds
  申请人：Nycomed Imaging AS

  公开号：US06117412A1

  公开（公告）日：2000-09-12

  A method of generating an image of a human or non-human animal body which comprises administering to said body a physiologically tolerable contrast enhancing amount of a non-cluster type bismuth compound, and methods of treating gastrointestinal disorders using the same. Diagnostic imaging contrast media comprising non-cluster type bismuth compounds are also disclosed, together with novel covalent non-cluster type bismuth compounds.

  一种生成人类或非人类动物身体图像的方法，包括向该身体施用一种生理耐受的增强对比剂量的非簇型铋化合物，以及使用该方法治疗胃肠道疾病的方法。还公开了包含非簇型铋化合物的诊断成像造影剂，以及新颖的共价非簇型铋化合物。
• Reversing Lewis acidity from bismuth to antimony
  作者：Deepti Sharma、Selvakumar Balasubramaniam、Sandeep Kumar、Eluvathingal D. Jemmis、Ajay Venugopal

  DOI：10.1039/d1cc03038h

  日期：——

  Investigations on the boundaries between the neutral and cationic models of (Mesityl)2EX (E = Sb, Bi and X = Cl−, OTf−) have facilitated reversing the Lewis acidity from bismuth to antimony. We use this concept to demonstrate a higher efficiency of (Mesityl)2SbOTf over (Mesityl)2BiOTf in the catalytic reduction of phosphine oxides to phosphines. The experiments supported with computations described

  对 (Mesityl) 2 EX (E = Sb, Bi 和 X = Cl - , OTf - )的中性和阳离子模型之间边界的研究促进了路易斯酸度从铋到锑的逆转。我们使用这个概念来证明 ( Mesityl ) 2 SbOTf 比 ( Mesityl ) 2 BiOTf 在将氧化膦催化还原为膦方面的效率更高。此处描述的计算所支持的实验将用于设计与催化相关的新路易斯酸。
• Rapid threefold cross-couplings with sterically bulky triarylbismuths under Pd–Cu dual catalysis
  作者：Maddali L. N. Rao、Ritesh J. Dhanorkar

  DOI：10.1039/c5ra23311a

  日期：——

  The threefold cross-coupling reactivity of sterically highly demanding bulky triarylbismuths was addressed with task specific Pd–Cu dual catalytic conditions. In this study, an unprecedented hitherto unknown cross-coupling reactivity of sterically bulky triarylbismuths was demonstrated with a diverse range of aryl iodides and bromides. The intermediacy and in situ formation of arylcopper was probed

  对空间要求苛刻的大体积三芳基铋的三重交叉偶联反应性是通过特定于任务的Pd-Cu双催化条件解决的。在这项研究中，证明了空前庞大的三芳基铋的前所未有的交叉偶合反应性与不同范围的芳基碘化物和溴化物。用间苯二酚探测芳基铜的中间和原位形成，以支持所提出的双重催化作用。这项研究为将体积庞大的铋试剂应用于三重芳基-芳基偶联反应开辟了一条简便的途径。