Novel arylaminopropane analogues and their use for the treatment of glaucoma
申请人:——
公开号:US20040110791A1
公开(公告)日:2004-06-10
Arylaminopropane analogues are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
NOVEL ARYLAMINOPROPANE ANALOGUES AND THEIR USE FOR THE TREATMENT OF GLAUCOMA
申请人:Alcon, Inc.
公开号:EP1392269A1
公开(公告)日:2004-03-03
US7071225B2
申请人:——
公开号:US7071225B2
公开(公告)日:2006-07-04
[EN] NOVEL ARYLAMINOPROPANE ANALOGUES AND THEIR USE FOR THE TREATMENT OF GLAUCOMA<br/>[FR] NOUVEAUX ANALOGUES D'ARYLAMINOPROPANE ET LEUR UTILISATION DANS LE TRAITEMENT DU GLAUCOME
申请人:ALCON INC
公开号:WO2002098400A1
公开(公告)日:2002-12-12
Arylaminopropane analogues are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
Synthesis of Naturally Occurring Pyranonaphthoquinones: (±) 9-Demethoxyeleutherin, (±) 9-Demethoxyisoeleutherin, and Pentalongin via Nef Reaction
作者:Rohan A. Limaye、Arun D. Natu、Madhusudan V. Paradkar
DOI:10.1080/00397911.2014.905600
日期:2014.9.2
provided the target molecules using a shorter route involving five simple chemical transformations with Nefreaction as a key step. All the intermediates and target molecules were completely characterized by spectral techniques and confirmed by comparison with literature data. Further we have extended Nef protocol toward formal synthesis of naturally occuring pyranonaphthoquinone pentalongin. We accomplished