4-trifluoroacetylamino-N-methylphthalimide | 895066-54-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 4-trifluoroacetylamino-N-methylphthalimide
• 英文别名: 2,2,2-trifluoro-N-(2-methyl-1,3-dioxoisoindol-5-yl)acetamide
• CAS: 895066-54-3
• 化学式: C₁₁H₇F₃N₂O₃
• mdl: MFCD07175909
• 分子量: 272.183
• InChiKey: CZBUFXDIPXPIFI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.181
• 拓扑面积：
  66.5
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  4-trifluoroacetylamino-N-methylphthalimide 、 四丁基碘化铵 以 乙腈 为溶剂， 反应 0.01h， 生成
  参考文献：
  名称：

  Fluorescence Response of a 4-Trifluoroacetylaminophthalimide to Iodide Ions upon 254 nm Irradiation in MeCN

  摘要：

  The title trifluoroacetylaminophthalimide derivative produced a violet fluorescence (lambda(FL)(max) 392 nm) in MeCN, and it displayed a green emission (lambda(FL)(max) 506 nm) after irradiation at 254 nm in the presence of iodide ions. The corresponding amidate ion of the trifluoroacetamide was identified as the green fluorescence emitter. The deprotonation reaction may be caused by proton-abstracting solvated electrons generated by a photochemical charge-transfer-to-solvent process from I(-) to MeCN.

  DOI：

  10.1021/ol801184x
• 作为产物：
  描述：

  N-甲基-4-氨基邻苯二甲酰亚胺 、 三氟乙酸酐 在 potassium hydrogencarbonate 作用下， 以 二氯甲烷 为溶剂， 反应 0.5h， 以80%的产率得到4-trifluoroacetylamino-N-methylphthalimide
  参考文献：
  名称：

  Fluorescence Response of a 4-Trifluoroacetylaminophthalimide to Iodide Ions upon 254 nm Irradiation in MeCN

  摘要：

  The title trifluoroacetylaminophthalimide derivative produced a violet fluorescence (lambda(FL)(max) 392 nm) in MeCN, and it displayed a green emission (lambda(FL)(max) 506 nm) after irradiation at 254 nm in the presence of iodide ions. The corresponding amidate ion of the trifluoroacetamide was identified as the green fluorescence emitter. The deprotonation reaction may be caused by proton-abstracting solvated electrons generated by a photochemical charge-transfer-to-solvent process from I(-) to MeCN.

  DOI：

  10.1021/ol801184x

文献信息

• Fluorescence Response of a 4-Trifluoroacetylaminophthalimide to Iodide Ions upon 254 nm Irradiation in MeCN
  作者：Hideki Okamoto、Hiroyuki Konishi、Mami Kohno、Kyosuke Satake

  DOI：10.1021/ol801184x

  日期：2008.7.17

  The title trifluoroacetylaminophthalimide derivative produced a violet fluorescence (lambda(FL)(max) 392 nm) in MeCN, and it displayed a green emission (lambda(FL)(max) 506 nm) after irradiation at 254 nm in the presence of iodide ions. The corresponding amidate ion of the trifluoroacetamide was identified as the green fluorescence emitter. The deprotonation reaction may be caused by proton-abstracting solvated electrons generated by a photochemical charge-transfer-to-solvent process from I(-) to MeCN.