N-[6-chloro-2-(3,5-dimethylpyrazol-1-yl)pyrimidin-4-yl]acetamide | 1014720-89-8

分子结构分类

有机化合物 - 有机氮化合物

中文名称

——

中文别名

——

英文名称

N-[6-chloro-2-(3,5-dimethylpyrazol-1-yl)pyrimidin-4-yl]acetamide

英文别名

N-(6-Chloro-2-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidin-4-yl)acetamide

N-[6-chloro-2-(3,5-dimethylpyrazol-1-yl)pyrimidin-4-yl]acetamide化学式

CAS

1014720-89-8

化学式

C₁₁H₁₂ClN₅O

mdl

——

分子量

265.702

InChiKey

XQGAYHZIANBQQZ-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

物化性质

密度：

1.42±0.1 g/cm3(Predicted)

计算性质

辛醇/水分配系数(LogP)：

1.8
重原子数：

18
可旋转键数：

2
环数：

2.0
sp3杂化的碳原子比例：

0.27
拓扑面积：

72.7
氢给体数：

1
氢受体数：

4

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
6-氯-2-(3,5-二甲基-吡唑-1-基)-嘧啶-4-基胺	4-chloro-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidine-6-amine	1014720-95-6	C₉H₁₀ClN₅	223.665

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	N-[2-(3,5-dimethylpyrazol-1-yl)-6-diethylamino-1-yl-pyrimidin-4-yl]acetamide	1032047-89-4	C₁₅H₂₂N₆O	302.379
——	N-[2-(3,5-dimethylpyrazol-1-yl)-6-pyrrolidin-1-ylpyrimidin-4-yl]acetamide	1032047-49-6	C₁₅H₂₀N₆O	300.363
——	N-[2-(3,5-dimethylpyrazol-1-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]acetamide	1101846-36-9	C₁₆H₂₃N₇O	329.405
——	N-[2-(3,5-dimethylpyrazol-1-yl)-6-morpholin-4-ylpyrimidin-4-yl]acetamide	1032048-04-6	C₁₅H₂₀N₆O₂	316.363
——	N-[2-(3,5-dimethylpyrazol-1-yl)-6-piperidin-1-ylpyrimidin-4-yl]acetamide	1032047-84-9	C₁₆H₂₂N₆O	314.39
——	N-[2-(3,5-dimethylpyrazol-1-yl)-6-(2-methylpyrrolidin-1-yl)pyrimidin-4-yl]acetamide	1101846-37-0	C₁₆H₂₂N₆O	314.39
——	N-[2-(3,5-dimethylpyrazol-1-yl)-6-(2-oxopyrrolidin-1-yl)pyrimidin-4-yl]acetamide	1032047-48-5	C₁₅H₁₈N₆O₂	314.347
——	N-[2-(3,5-dimethylpyrazol-1-yl)-6-(2-propylpyrrolidin-1-yl)pyrimidin-4-yl]acetamide	1032047-62-3	C₁₈H₂₆N₆O	342.444
N-[6-(3,5-二甲基-1H-吡唑-1-基)-2-((E)-苯乙烯基)嘧啶-4-基]乙酰胺	N-[6-(3,5-dimethyl-1H-pyrazol-1-yl)-2((E)-styryl)pyrimidin-4-yl]acetamide	1014720-91-2	C₁₉H₁₉N₅O	333.393
——	N-[2-(3,5-dimethylpyrazol-1-yl)-6-((R)-2-hydroxymethylpyrrolidin-1-yl)pyrimidin-4-yl]acetamide	1032047-68-9	C₁₆H₂₂N₆O₂	330.39
——	N-[2-(3,5-dimethyl-pyrazol-1-yl)-6-phenyl-pyrimidin-4-yl]-acetamide	1074762-01-8	C₁₇H₁₇N₅O	307.355
——	N-[2-(3,5-dimethylpyrazol-1-yl)-6-(2-(R)-methoxymethylpyrrolidin-1-yl)pyrimidin-4-yl]acetamide	1032047-47-4	C₁₇H₂₄N₆O₂	344.417
N-[2-(3,5-二甲基吡唑-1-基)-6-(2-甲氧基甲基吡咯烷-1-基)嘧啶-4-基]乙酰胺	N-[2-(3,5-dimethylpyrazol-1-yl)-6-(2-methoxymethylpyrrolidin-1-yl)pyrimidin-4-yl]acetamide	1032047-57-6	C₁₇H₂₄N₆O₂	344.417
N-[2-(3,5-二甲基吡唑-1-基)-6-(2-(S)-甲氧基甲基吡咯烷-1-基)嘧啶-4-基]乙酰胺	N-[2-(3,5-dimethylpyrazol-1-yl)-6-(2-(S)-methoxymethylpyrrolidin-1-yl)pyrimidin-4-yl]acetamide	1032048-05-7	C₁₇H₂₄N₆O₂	344.417
——	N-[2-(3,5-dimethylpyrazol-1-yl)-6-[(R)-2-(2-methoxyethyl)piperidin-1-yl]pyrimidin-4-yl]acetamide	1032048-03-5	C₁₉H₂₈N₆O₂	372.47
——	N-[2-(3,5-dimethyl-pyrazol-1-yl)-6-(3-hydroxy-phenyl)-pyrimidin-4-yl]-acetamide	1061750-36-4	C₁₇H₁₇N₅O₂	323.354
N-[2-(3,5-二甲基吡唑-1-基)-6-(2-乙氧基甲基吡咯烷-1-基)嘧啶-4-基]乙酰胺	N-[2-(3,5-dimethylpyrazol-1-yl)-6-(2-ethoxymethylpyrrolidin-1-yl)pyrimidin-4-yl]acetamide	1032048-01-3	C₁₈H₂₆N₆O₂	358.443
——	N-[2-(3,5-dimethylpyrazol-1-yl)-6-((R)-2-methoxymethyl-5-methylpyrrolidin-1-yl)pyrimidin-4-yl]acetamide	1101846-39-2	C₁₈H₂₆N₆O₂	358.443
——	N-(2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-(4-methoxyphenyl)pyrimidin-4-yl)acetamide	1074762-04-1	C₁₈H₁₉N₅O₂	337.381
——	N-[6-(2-chloropyridin-4-yl)-2-(3,5-dimethyl-pyrazol-1-yl)-pyrimidin-4-yl]-acetamide	1061750-09-1	C₁₆H₁₅ClN₆O	342.788
——	N-(2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-m-tolylpyrimidin-4-yl)acetamide	1074762-05-2	C₁₈H₁₉N₅O	321.382
——	N-(2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-(3,5-dimethylphenyl)pyrimidin-4-yl)acetamide	1074762-09-6	C₁₉H₂₁N₅O	335.409
——	N-[2-(3,5-dimethyl-pyrazol-1-yl)-6-(3-methoxyphenyl)-pyrimidin-4-yl]-acetamide	1074762-03-0	C₁₈H₁₉N₅O₂	337.381
——	N-(6-(3,5-difluorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidin-4-yl)acetamide	1074762-12-1	C₁₇H₁₅F₂N₅O	343.336
——	N-[6-(3,5-dimethoxyphenyl)-2-(3,5-dimethyl-pyrazol-1-yl)-pyrimidin-4-yl]-acetamide	1074762-11-0	C₁₉H₂₁N₅O₃	367.407
——	N-(6-(3-cyanophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidin-4-yl)acetamide	1074762-06-3	C₁₈H₁₆N₆O	332.365
——	N-(6-(3-(cyanomethyl)phenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidin-4-yl)acetamide	1074762-07-4	C₁₉H₁₈N₆O	346.392
——	N-[2-(3,5-dimethyl-pyrazol-1-yl)-6-(3-formyl-phenyl)-pyrimidin-4-yl]-acetamide	1061750-42-2	C₁₈H₁₇N₅O₂	335.365
——	N-[-2-(3,5-dimethyl-pyrazol-1-yl)-6-(3-hydroxymethyl-phenyl)-pyrimidin-4-yl]-acetamide	1061750-39-7	C₁₈H₁₉N₅O₂	337.381
——	N-[2-(3,5-dimethyl-pyrazol-1-yl)-6-(3-fluoro-5-hydroxy-phenyl)-pyrimidin-4-yl]-acetamide	1061750-32-0	C₁₇H₁₆FN₅O₂	341.345
——	N-[6-(6-chloropyridin-2-yl)-2-(3,5-dimethyl-pyrazol-1-yl)-pyrimidin-4-yl]-acetamide	1061750-08-0	C₁₆H₁₅ClN₆O	342.788
——	N-[6-(3,4-dihydro-1H-isoquinolin-2-yl)-2-(3,5-dimethylpyrazol-1-yl)pyrimidin-4-yl]acetamide	1032047-51-0	C₂₀H₂₂N₆O	362.434
——	N-[2-(3,5-dimethylpyrazol-1-yl)-6-((S)-4-methoxy-(R)-2-methoxymethylpyrrolidin-1-yl)pyrimidin-4-yl]acetamide	1101846-42-7	C₁₈H₂₆N₆O₃	374.443
——	N-[2-(3,5-dimethylpyrazol-1-yl)-6-((R)-4-methoxy-(R)-2-methoxymethylpyrrolidin-1-yl)pyrimidin-4-yl]acetamide	1032047-64-5	C₁₈H₂₆N₆O₃	374.443
——	N-[6-(5-bromopyridin-3-yl)-2-(3,5-dimethyl-pyrazol-1-yl)-pyrimidin-4-yl]-acetamide	1061750-13-7	C₁₆H₁₅BrN₆O	387.239
——	N-(2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-(3-(trifluoromethyl)phenyl)pyrimidin-4-yl)acetamide	1074762-08-5	C₁₈H₁₆F₃N₅O	375.353
——	N-(2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-(2,5-dimethylphenyl)pyrimidin-4-yl)acetamide	1074762-10-9	C₁₉H₂₁N₅O	335.409
——	(S)-1-[6-acetylamino-2-(3,5-dimethylpyrazol-1-yl)pyrimidin-4-yl]pyrrolidine-2-carboxylic acid methyl ester	1101846-38-1	C₁₇H₂₂N₆O₃	358.4
——	(R)-1-[6-acetylamino-2-(3,5-dimethylpyrazol-1-yl)pyrimidin-4-yl]pyrrolidine-2-carboxylic acid methyl ester	1032047-98-5	C₁₇H₂₂N₆O₃	358.4
——	N-(2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-(2-methoxyphenyl)pyrimidin-4-yl)acetamide	1074762-02-9	C₁₈H₁₉N₅O₂	337.381