Room-Temperature Palladium-Catalyzed CH Activation:<i>ortho</i>-Carbonylation of Aniline Derivatives
作者:Chris E. Houlden、Marc Hutchby、Chris D. Bailey、J. Gair Ford、Simon N. G. Tyler、Michel R. Gagné、Guy C. Lloyd-Jones、Kevin I. Booker-Milburn
DOI:10.1002/anie.200805842
日期:2009.2.23
Pd and CO—ureally got me! The title reaction proceeds efficiently at 18 °C under CO (1 atm) with 5 % [Pd(OTs)2(MeCN)2] as precatalyst. Depending on the solvents used, either anthranilates or cyclic imides can be obtained in high yields (see picture, BQ=benzoquinone, Ts=4‐toluenesulfonyl).
Pd 和 CO - 真的抓住了我!标题反应在 18 °C 下在 CO (1 atm) 下有效进行,使用 5% [Pd(OTs) 2 (MeCN) 2 ] 作为预催化剂。根据所使用的溶剂,可以高产率获得邻氨基苯甲酸酯或环状酰亚胺(见图,BQ=苯醌,Ts=4-甲苯磺酰基)。
Bitter, I.; Szoecs, L.; Toeke, L., Acta Chimica Academiae Scientiarum Hungaricae, 1981, vol. 107, p. 57 - 66
作者:Bitter, I.、Szoecs, L.、Toeke, L.
DOI:——
日期:——
Regioselective bromination of aryl ureas with Phenyliodine(III) diacetate and potassium bromide
作者:Chun-Meng Wang、Jian-Yao Du、Jin-Yang Zhang、Kai-Xiang Tang、Tian-Hong Gao、Yun-Gen Xu、Li-Ping Sun
DOI:10.1016/j.tet.2019.130621
日期:2019.11
An efficient regioselective and operationally simple urea bromination method utilizing PIDA and potassium bromide is reported. This protocol proved to be effective on a broad range of substituted ureas in acetone at room temperature, forming the p-brominated compounds in 44–86% yields.