benzoic acid-[5α-ergosten-(8(14))-yl-(3β)-ester] | 6055-59-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: benzoic acid-[5α-ergosten-(8(14))-yl-(3β)-ester]
• 英文别名: Benzoesaeure-[5α-ergosten-(8(14))-yl-(3β)-ester]；alpha-Ergostenol benzoate；[(3S,5S,9R,10S,13R,17R)-17-[(2R,5S)-5,6-dimethylheptan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] benzoate
• CAS: 6055-59-0
• 化学式: C₃₅H₅₂O₂
• 分子量: 504.797
• InChiKey: IOHGSXJQBQDGAE-OLCBBKHWSA-N

物化性质

• 沸点：
  571.9±49.0 °C(Predicted)
• 密度：
  1.03±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  10.5
• 重原子数：
  37
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.74
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  盐酸 、 氯仿 、 benzoic acid-[5α-ergosten-(8(14))-yl-(3β)-ester] 生成 benzoic acid-(5α-ergosten-(14)-yl-(3β)-ester)
  参考文献：
  名称：

  229.固醇类的研究。第XIV部分。Β-麦角甾醇及其衍生物

  摘要：

  DOI：

  10.1039/jr9320001708
• 作为产物：
  描述：

  麦角固醇 在 吡啶 、 乙醚 、 铂 作用下， 生成 benzoic acid-[5α-ergosten-(8(14))-yl-(3β)-ester]
  参考文献：
  名称：

  Prediction Based on Mean Subset

  摘要：

  Shrinkage methods have traditionally been applied in prediction problems. In this article we develop a shrinkage method (mean subset) that forms an average of regression coefficients from individual subsets of the explanatory variables. A Bayesian approach is taken to derive an expression of how the coefficient vectors from each subset should be weighted. It is not computationally feasible to calculate the mean subset coefficient vector for larger problems, and thus we suggest an algorithm to find an approximation to the mean subset coefficient vector. In a comprehensive Monte Carlo simulation study, it is found that the proposed mean subset method has superior prediction performance than prediction based on the best subset method, and in some settings also better than the ridge regression and lasso methods. The conclusions drawn from the Monte Carlo study is corroborated in an example in which prediction is made using spectroscopic data.

  DOI：

  10.1198/004017002188618563

文献信息

• 158. The application of the method of molecular rotation differences to steroids. Part IV. Optical anomalies
  作者：D. H. R. Barton、J. D. Cox

  DOI：10.1039/jr9480000783

  日期：——
• The Role of Radial Clearance on the Performance of Foil Air Bearings
  作者：Kevin Radil、Samuel Howard、Brian Dykas

  DOI：10.1080/10402000208982578

  日期：2002.1

  Load capacity tests were conducted to determine how radial clearance variations affect the load capacity coefficient of foil air bearings. Two Generation III foil air bearings with the same design but possessing different initial radial clearances were tested at room temperature against an as-ground PS304 coated journal operating at 30000 rpm. Increases in radial clearance were accomplished by reducing the journal's outside diameter via an in-place grinding system. Front each load capacity test the bearing load capacity coefficient was calculated from the rule-of-thumb (ROT) model developed for foil air bearings.The test results indicate that, in terms of the load capacity coefficient, radial clearance has a direct impact on the performance of the foil air bearing. Each test bearing exhibited an optimum radial clearance that resulted in a maximum load capacity coefficient. Relative to this optimum value are two separate operating regimes that are governed by different modes of failure. Bearings operating with radial clearances less than the optimum exhibit load capacity coefficients that are a strong function of radial clearance and are prone to a thermal runaway failure mechanism and bearing seizure. Conversely, a bearing operating with a radial clearance m,ice the optimum suffered only a 20% decline in its maximum load capacity coefficient and did not experience any thermal management problems. However, it is unknown to what degree these changes in radial clearance had on other performance parameters, such (is the stiffness and damping properties of the bearings.
• Thrust-Washer Evaluation of Self-Lubricating PS304 Composite Coatings in High Temperature Sliding Contact
  作者：Thierry A. Blanchet、Jong-Hwan Kim、Salvadore J. Calabrese、Christopher Dellacorte

  DOI：10.1080/10402000208982579

  日期：2002.1

  PS304 self-lubricating composite coatings were successfully deposited on steel substrates at various plasma spray facilities using mixtures blended from commercially obtained constituent particles. Coatings were evaluated in thrust-washer tests against Inconel X-750 at low contact pressures to 40kPa, sliding speed of 5.4m/s, and either ambient temperature or 500 degreesC chosen to simulate conditions in air foil bearings during startup and shutdown contact. Wear factors for all PS304 coatings tested, regardless of contact pressure and temperature, ranged from 1-3*10(-4) mm(3)/Nm while coefficients of friction of approximately mu = 0.5 were measured in all cases. While wear and friction behavior of PS304 in air foil bearings appear to have been simulated, surface roughening was observed in these thrust-washer tests which used continuous sliding contact, as opposed to the evolution of smoother surfaces observed in high-temperature foil bearings experiencing cyclic startup/shutdown. Wear-induced surface smoothening of PS304 was additionally simulated in thrust-washer tests with sliding contact instead imposed intermittently.
• Beta-Ergostenol. II
  作者：Frederick W. Heyl、Merrill C. Hart、Harold Emerson

  DOI：10.1021/ja01334a040

  日期：1933.7
• Wieland; Rath; Hesse, Justus Liebigs Annalen der Chemie, 1941, vol. 548, p. 34,42, 45
  作者：Wieland、Rath、Hesse

  DOI：——

  日期：——