1,5-diazacyclodecane | 6573-62-2

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1,5-diazacyclodecane
• 英文别名: 1,5-Diazecane
• CAS: 6573-62-2
• 化学式: C₈H₁₈N₂
• mdl: MFCD19218570
• 分子量: 142.244
• InChiKey: QIBCHPNVYOPDTP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  24.1
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,5-diazacyclodecane 在 lithium aluminium tetrahydride 、 magnesium sulfate 作用下， 以 乙二醇二甲醚 、 二氯甲烷 为溶剂， 反应 24.0h， 生成 1,7-二氮杂双环[5.4.3]十四烷
  参考文献：
  名称：

  Synthesis of medium-ring bicyclic bridgehead diamines from monocyclic diamines via α-aminoammonium ions

  摘要：

  DOI：

  10.1016/s0040-4039(00)88382-3
• 作为产物：
  描述：

  5-氯戊醛 在 diisobutylaluminum hydride 、 magnesium sulfate 作用下， 以 二氯甲烷 为溶剂， 生成 1,5-diazacyclodecane
  参考文献：
  名称：

  Synthesis of medium-ring bicyclic bridgehead diamines from monocyclic diamines via α-aminoammonium ions

  摘要：

  DOI：

  10.1016/s0040-4039(00)88382-3

文献信息

• High yields of diazabicycloalkanes and oxazabicycloalkanes containing medium and large rings from rhodium-catalysed hydroformylation reactions without the need for high dilution conditions
  作者：David J. Bergmann、Eva M. Campi、W. Roy Jackson、Antonio F. Patti

  DOI：10.1039/a903638e

  日期：——

  Rhodium-catalysed reactions of N-alkenyl-1,3-diaminopropanes and N-alkenylaminoethanols give diazabicycloalkanes and oxazabicycloalkanes containing medium or large rings in excellent yields.

  铑催化的N-烯基-1,3-二胺丙烷和N-烯基氨基乙醇反应能高产率地生成含有中环或大环的二氮双环烷烃和氧氮双环烷烃。
• SILICONE COMPOUND HAVING A RADICAL-POLYMERIZABLE GROUP AND A METHOD FOR THE PREPARATION THEREOF
  申请人：SHIN-ETSU CHEMICAL CO., LTD.

  公开号：US20150087853A1

  公开（公告）日：2015-03-26

  A purpose of the present invention is to provide a polymerizable group-containing silicone compound which is liquid at room temperature, has good handling properties and compatibility with other polymerizable monomers. The present invention provides a silicone compound represented by the general formula (1) which has a structure represented by the following formula (2) or (3): wherein R c is an alkyl group having 1 to 10 carbon atoms and Z is a radical-polymerizable group; wherein p 1 and p 2 are, independently of each other, positive integers such that a total number of p 1 and p 2 is 3 to 10, and Z is a radical-polymerizable group; and has a silicone structure bonded to the aforesaid formula (2) or (3) via a substituted or unsubstituted divalent hydrocarbon group having 1 to 10 carbon atoms. The present invention further provides a method for preparation the aforesaid silicone compound.

  本发明的目的是提供一种聚合物化基团含硅化合物，该化合物在室温下为液体，具有良好的操控性能和与其他可聚合单体的相容性。本发明提供了一种由一般式(1)表示的硅氧烷化合物，其具有以下式(2)或(3)表示的结构：其中Rc是具有1至10个碳原子的烷基基团，Z是一个基团-可聚合基团；其中p1和p2是彼此独立的正整数，使得p1和p2的总数为3至10，Z是一个基团-可聚合基团；并且具有通过具有1至10个碳原子的取代或未取代的二价碳氢基团与上述式(2)或(3)结合的硅氧烷结构。本发明还提供了制备上述硅氧烷化合物的方法。
• MACROCYCLIC PYRIMIDINE DERIVATIVES
  申请人：Liu Huaqing

  公开号：US20090253678A1

  公开（公告）日：2009-10-08

  Macrocyclic pyrimidine compounds, compositions comprising such compounds, methods for making the compounds, and methods of treating and preventing the progression of diseases, conditions, and disorders using such compounds and compositions are described herein.

  本文描述了大环嘧啶化合物、包含此类化合物的组合物、制备此类化合物的方法以及使用此类化合物和组合物治疗和预防疾病、病症和障碍的方法。
• The out,out to out,in transition for 1,(n+2)-diazabicyclo[n.3.1]alkanes
  作者：Roger W. Alder、Edgar Heilbronner、Evi Honegger、Alan B. McEwen、Richard E. Moss、Edward Olefirowicz、Peter A. Petillo、Richard B. Sessions、Gary R. Weisman

  DOI：10.1021/ja00068a015

  日期：1993.7

  Hexahydropyrimidines N,N-bridged by a chain of n methylene groups (1,(n + 2)-diazabicyclo[n.3.1]alkanes) adopt out,out (axial,axial) structures for n = 2, 3, and 4. When n = 5, the photoelectron spectrum shows evidence of the presence of some of the out,in (axial,equatorial) isomer in the gas phase, although none can be found in solution. When n = 6, the compound is apparently entirely out,in in the gas phase but exists as a mixture of out,out and out,in conformers in solution. For n = 7, only the diamond lattice out,in isomer can be detected in solution. These experimental data are correlated with,force field (MM2) calculations; multiple minimum search methods have been used to locate all low-energy conformations. Semiempirical calculations (MNDO, AMI, and PM3) have been carried out on model systems. Related tricyclic bis-aminals having 10- and 12-membered rings have also been studied. They adopt [2323] and [3333] conformations, respectively, each having out,in (equatorial,axial) bridged hexahydropyrimidine rings. For several of the compounds, dynamic NMR processes are observed, and possible mechanisms for these are discussed.
• ALDER, R. W.;EASTMENT, P.;MOSS, R. E.;SESSIONS, R. B.;STRINGFELLOW, M. A., TETRAHEDRON LETT., 1982, 23, N 40, 4181-4184
  作者：ALDER, R. W.、EASTMENT, P.、MOSS, R. E.、SESSIONS, R. B.、STRINGFELLOW, M. A.

  DOI：——

  日期：——