2,3,4,6-Tetrachloro-5-cyanobenzamide | 61073-19-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,3,4,6-Tetrachloro-5-cyanobenzamide
• CAS: 61073-19-6
• 化学式: C₈H₂Cl₄N₂O
• 分子量: 283.9
• InChiKey: XTFCOCGBWMNRKW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  66.9
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Method and reagents for binding chemical analytes to a substrate surface, and related analytical devices and diagnostic techniques
  申请人：Hewlett-Packard Company

  公开号：EP0657737A2

  公开（公告）日：1995-06-14

  A method for detecting an analyte of interest in a sample includes the steps of binding the analyte to the surface of a substrate through a biotin-biotin binding protein interaction, contacting the surface-bound analyte with a quantitatively detectable analyte-binding moiety that binds thereto, measuring the quantity of detectable moiety bound to the substrate surface (11) and deriving therefrom the quantity of analyte in solution. A preferred use for the present method is in conjunction with a piezoelectric surface transverse wave device.

  一种检测样品中感兴趣的分析物的方法包括以下步骤：通过生物素-生物素结合蛋白的相互作用将分析物与基质表面结合；将表面结合的分析物与定量检测的分析物结合分子接触；测量与基质表面结合的可检测分子的数量（11），并由此得出溶液中分析物的数量。本方法最好与压电表面横波装置结合使用。
• Process for producing cyanobenzoic acid derivatives
  申请人：Showa Denko Kabushiki Kaisha

  公开号：EP0989115A2

  公开（公告）日：2000-03-29

  A process for producing a cyanobenzoic acid compound, a cyanobenzamide compound, an alkyl cyanobenzoate compound, and a cyanobenzoyl chloride compound, which are useful intermediates for a variety of chemicals such as pharmaceuticals, agrochemicals, liquid crystals, and monomers for functional polymers. One nitrile group of an easily available phthalonitrile compound is selectively hydrolyzed to thereby produce a cyanobenzamide compound with high selectivity and yield. The cyanobenzamide compound thus-produced is transformed under acidic conditions into a cyanobenzoic acid compound and a cyanobenzoate ester compound without the cyano group of the benzene ring being damaged.

  一种生产氰基苯甲酸化合物、氰基苯甲酰胺化合物、氰基苯甲酸烷基酯化合物和氰基苯甲酰氯化合物的工艺，这些化合物是多种化学品（如医药、农用化学品、液晶和功能聚合物单体）的有用中间体。一种易于获得的邻苯二腈化合物的一个腈基被选择性水解，从而以高选择性和高产率生成一种氰基苯甲酰胺化合物。由此生成的氰基苯甲酰胺化合物在酸性条件下可转化为氰苯甲酸化合物和氰苯甲酸酯化合物，而苯环上的氰基不会受到破坏。
• US5527711A
  申请人：——

  公开号：US5527711A

  公开（公告）日：1996-06-18
• US6433211B1
  申请人：——

  公开号：US6433211B1

  公开（公告）日：2002-08-13
• [EN] IMMUNOASSAY FOR TETRACHLOROISOPHTHALONITRILE (CHLOROTHALONIL3), ITS DERIVATIVES AND BREAKDOWN PRODUCTS<br/>[FR] DOSAGE IMMUNOLOGIQUE POUR LA DETECTION DU TETRACHLOROISOPHTHALONITRILE (CHLORTHALONIL3), SES DERIVES ET PRODUITS DE DEGRADATION
  申请人：ISK BIOSCIENCES CORPORATION

  公开号：WO1994023018A1

  公开（公告）日：1994-10-13

  (EN) Novel derivatives of chlorothalonil$m(3) (tetrachloroisophthalonitrile, TCPN), permit conjugation of the TCPN derivative to a carrier useful as an immunogen to induce antibodies specific for TCPN or a TCPN metabolite, or a screening antigen to detect such antibodies. Polyclonal and monoclonal antibodies specific for TCPN or a TCPN metabolite, as well as hybridoma cells producing such antibodies are disclosed. Also provided are immunoassay methods for detection and quantitation of pesticide chemicals, in particular, the fungicide TCPN or a TCPN metabolite, and kits containing a TCPN derivative screening antigen, an anti-TCPN or anti-TCPN metabolite antibody useful for performing the immunoassays.(FR) De nouveaux dérivés de chlorthalonil$m(3) (tétrachloroisophthalonitrile, TCPN) permettent de conjuguer le dérivé de TCPN avec un porteur pouvant être utilisé comme un immunogène afin d'induire des anticorps spécifiques au TCPN ou à un métabolite de TCPN, ou un antigène de criblage permettant de détecter ces anticorps. Des anticorps polyclonaux et monoclonaux spécifiques du TCPN ou d'un métabolite de TCPN ainsi que des cellules d'hybridomes produisant ces anticorps sont décrits. L'invention concerne également des procédés de dosage immunologique utilisés dans la détection et la quantification de produits chimiques pesticides, notamment le fongicide TCPN ou un métabolite de TCPN, et des kits contenant un antigène de criblage du dérivé du TCPN, un anticorps anti-TCPN ou antti-métabolite de TCPN utile dans la réalisation des dosages immunologiques.