2,4-dichlorophenoxy acetic acid ethylene glycol | 38383-43-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,4-dichlorophenoxy acetic acid ethylene glycol
• 英文别名: 2-Hydroxyethyl 2-(2,4-dichlorophenoxy)acetate
• CAS: 38383-43-6
• 化学式: C₁₀H₁₀Cl₂O₄
• 分子量: 265.093
• InChiKey: PYRIVSYMXLPCNV-UHFFFAOYSA-N

物化性质

• 沸点：
  176-178 °C(Press: 1 Torr)
• 密度：
  1.3896 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2,4-dichlorophenoxy acetic acid ethylene glycol 在 硫酸 作用下， 以 水 为溶剂， 反应 5.0h， 以221 g的产率得到2,4-二氯苯氧乙酸
  参考文献：
  名称：

  一种2,4-二氯苯氧乙酸的制备方法

  摘要：

  本发明提供了一种2,4‑二氯苯氧乙酸的制备方法，包括以下步骤，首先将多元醇和卤代乙酸进行酯化反应，得到卤代乙酸酯；然后将上述步骤得到的卤代乙酸酯与2,4‑二氯酚盐进行反应，得到2,4‑二氯苯氧乙酸酯；最后在复合催化剂的作用下，将上述步骤得到的2,4‑二氯苯氧乙酸酯进行水解反应，得到2,4‑二氯苯氧乙酸和多元醇；所述多元醇为C原子数大于等于2的多元醇。本发明调整工艺路线，从基础上进行创造性改进，该制备方法，工艺简单，条件温和，水解副产物少，产物纯度高，转化率和收率较高，而且中间体卤代乙酸酯稳定，适合大规模工业化生产。

  公开号：

  CN108424365A
• 作为产物：
  描述：

  2,4-二氯苯氧乙酸 、 乙二醇 在 硫酸 作用下， 反应 2.5h， 以86.8%的产率得到2,4-dichlorophenoxy acetic acid ethylene glycol
  参考文献：
  名称：

  苯并[1,2,3]噻二唑-7-羧酸酯衍生物作为植 物抗病激活剂的应用

  摘要：

  发明涉及式(I)所示的苯并[1，2，3]噻二唑‑7‑羧酸酯衍生物作为植物抗病激活剂的应用。该系列化合物对植物的多种疾病具有一定的防治效果。

  公开号：

  CN102532058B

文献信息

• Design, synthesis and herbicidal activities of novel self-dispreading phenoxy carboxylic acid derivatives for the control of water hyacinth floating on the water surface
  作者：Lv-Yin Zheng、Ren-Miao Wu、Wei Guo、Wen-Hua You、Yan-Lan Ling、Xiao-Lin Fan

  DOI：10.1016/j.cclet.2015.04.008

  日期：2015.8

  A series of novel self-dispreading phenoxy carboxylic acid derivatives were designed and synthesized by I-2 catalyzed one-step reaction. Their structures were confirmed by IR, NMR, and HRMS. The derivatives can self-spread and float on the water surface. Preliminary bioassays showed that some compounds, 3i-3p, had excellent herbicidal activities against water hyacinth. This strategy provided a novel approach for the water hyacinth control. (C) 2015 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
• New Compounds. New Compounds as Plant Growth Regulators
  作者：Melvin Newman、William Fones、Mary Renoll

  DOI：10.1021/ja01195a604

  日期：1947.3
• Novel Benzo-1,2,3-thiadiazole-7-carboxylate Derivatives As Plant Activators and the Development of Their Agricultural Applications
  作者：Qingshan Du、Weiping Zhu、Zhenjiang Zhao、Xuhong Qian、Yufang Xu

  DOI：10.1021/jf203974p

  日期：2012.1.11

  Plant activators are a novel kind of agrochemicals that could induce resistance in many plants against a broad spectrum of diseases. To date, only few plant activators have been commercialized. In order to develop novel plant activators, a series of benzo-1,2,3-thiadiazole-7-carboxylate derivatives were synthesized, and the structures were characterized by H-1 NMR, IR, elemental analyses, and HRMS or MS. Their potential systemic acquired resistance as plant activators was evaluated as well. Most of them showed good activity, especially, fluoro-containing compounds 3d and 3e, which displayed excellent SAR-inducing activity against cucumber Erysiphe cichoracearum and Colletotrichum lagenarium in assay screening. Field test results illustrated that compounds 3d and 3e were more potent than the commercial plant activator, S-methyl benzo[1,2,3]thiadiazole-7-carbothioate (BTH) toward these pathogens. Further, the preparation of compound 3d is more facile than BTH with lower cost, which will be helpful for further applications in agricultural plant protection.
• MAMEDOV SH. A.; AXMEDOV V. S., AZEHRB. KIMJA ZH., AZERB. XIM. ZH., 1978, HO 6, 59-65
  作者：MAMEDOV SH. A.、 AXMEDOV V. S.

  DOI：——

  日期：——
• XYDYROV, D. N.;ALIEV, V. S.;ALIEV, S. M.;PROMONENKOV, V. K.;LIPUSHKINA, N+
  作者：XYDYROV, D. N.、ALIEV, V. S.、ALIEV, S. M.、PROMONENKOV, V. K.、LIPUSHKINA, N+

  DOI：——

  日期：——