(E)-2-(pent-1-en-1-yl)furan | 20992-69-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 杂芳族化合物
• 英文名称: (E)-2-(pent-1-en-1-yl)furan
• 英文别名: 2-(1-Pentenyl)furan；2-[(E)-pent-1-enyl]furan
• CAS: 20992-69-2
• 化学式: C₉H₁₂O
• 分子量: 136.194
• InChiKey: LKSYSJTUBQSZBS-GQCTYLIASA-N

物化性质

• 沸点：
  178.2±9.0 °C(Predicted)
• 密度：
  0.931±0.06 g/cm3(Predicted)
• LogP：
  3.923 (est)
• 保留指数：
  1000;1009;1058

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  13.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (E)-2-(pent-1-en-1-yl)furan 在 氢气 、 镍 作用下， 生成 4-壬酮
  参考文献：
  名称：

  Schuikin; Bel'skii, Zhurnal Obshchei Khimii, 1957, vol. 27, p. 402,404; engl. Ausg. S. 453, 455

  摘要：

  DOI：
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 aluminum oxide 作用下， 生成 (E)-2-(pent-1-en-1-yl)furan
  参考文献：
  名称：

  Schuikin; Bel'skii, Zhurnal Obshchei Khimii, 1957, vol. 27, p. 402,404; engl. Ausg. S. 453, 455

  摘要：

  DOI：

文献信息

• 1H-pyrrole-2,4-dicarbonyl-derivatives and their use as flavoring agents
  申请人：IMAX Discovery GmbH

  公开号：EP2832233A1

  公开（公告）日：2015-02-04

  The present invention primarily relates to 1H-pyrrole-2,4-dicarbonyl-derivatives of Formula (I) wherein R1, R2, R3, Z. Z' and J are as defined in the description, to mixtures thereof and to the use thereof as flavoring agents. The compounds in accordance with the present invention are suitable for producing, imparting, or intensifying an umami flavor. The invention further relates to flavoring mixtures, compositions for oral consumption as well as ready-to-eat, ready-to-use and semifinished products, comprising an effective amount of the compound of Formula (I) or of a mixture of compounds of Formula (I) and to specific methods for producing, imparting, modifying and/or intensifying specific flavor impressions.

  本发明主要涉及式(I)的1H-吡咯-2,4-二羰基衍生物，其中R1、R2、R3、Z、Z'和J按描述定义，及其混合物，以及用作调味剂的使用。根据本发明的化合物适用于生产、赋予或增强鲜味。本发明进一步涉及包含式(I)化合物或式(I)化合物混合物的有效量的调味混合物、口腔消费的组成物以及即食、即用和半成品，以及用于生产、赋予、改变和/或增强特定风味印象的特定方法。
• Imidazo[1,2-a]pyridine-ylmethyl-derivatives and their use as flavoring agents
  申请人：IMAX Discovery GmbH

  公开号：EP2832234A1

  公开（公告）日：2015-02-04

  The present invention primarily relates to imidazo[1,2-a]pyridine-ylmethyl-derivatives of Formula (I) wherein R1, R2, X, W e J are as defined in the description, to mixtures thereof and to the use thereof as flavoring agents. The compounds in accordance with the present invention are suitable for producing, imparting, or intensifying an umami flavor. The invention further relates to flavoring mixtures, compositions for oral consumption as well as ready-to-eat, ready-to-use and semifinished products, comprising an effective amount of the compound of Formula (I) and to specific methods for producing, imparting, modifying and/or intensifying specific flavor impressions.

  本发明主要涉及式(I)的咪唑[1,2-a]吡啶基甲基衍生物，其中R1、R2、X、W和J如描述中定义，以及涉及它们的混合物和使用它们作为调味剂。根据本发明的化合物适合于产生、赋予或增强鲜味。本发明进一步涉及调味混合物、口腔摄入的配方以及包含有效量的式(I)化合物的即食、即用和半成品，以及用于生产、赋予、改变和/或增强特定风味印象的特定方法。
• Reactions en milieu heterogene solide-liquide faiblement hydrate III
  作者：Y. Le Bigot、R. Elgharbi、M. Delmas、A. Gaset

  DOI：10.1016/s0040-4020(01)87536-0

  日期：1986.1

  The use of alkaline carbonates in a slighty hydrated solid-liquid protic organic media allowed the synthesis of alkenes from polyfunctionnal aldehydes with high yield in a E preferential stereochemistry specially with non-stabilized ylides. It has been shown that the decomposition of the threo betain acts as the determining step of the reaction.

  在略微水合的固液质子有机介质中使用碱式碳酸盐可以从多官能醛中以较高的收率在E优先立体化学中，特别是与非稳定化的叶立德合成烯烃。已显示苏糖甜菜碱的分解充当反应的确定步骤。
• Stereoselective Rhodium-Catalyzed Isomerization of Stereoisomeric Mixtures of Arylalkenes
  作者：Tao Li、Wanxiang Zhao、Hongxuan Yang、Wenke Dong、Wencan Wang

  DOI：10.1055/s-0040-1707166

  日期：2020.10

  Abstract A new efficient method for the synthesis of a high ratio of E-alkenes from E/Z mixtures of alkenes with B2pin2 in the presence of a rhodium catalyst is described. This reaction features mild reaction conditions, broad functional group tolerance, and highly great application potential.

  摘要 用于高比率的合成的新有效的方法ë从烯烃é / Ž与乙烯的混合物2销2在铑催化剂的存在下进行说明。该反应具有温和的反应条件，宽泛的官能团耐受性和极高的应用潜力。
• Compositions of stable bioactive metabolites of docosahexaenoic (DHA) and eicosapentaenoic (EPA) acids
  申请人：Ghosal Shibnath

  公开号：US20050282781A1

  公开（公告）日：2005-12-22

  An invention that adduces cogent evidence to establish that oxygenated dibenzo-α-pyrones (DBPs and their conjugates), the major bioactives of shilajit (Ayurvedic vitalizer), have their origin, at least partly, in EPA and DHA. Earlier research has shown that, in mammals, C-20 PUFAs are metabolized by oxygenases and other enzymes to produce short-lived prostaglandins, leukotrienes and thromboxanes that bind to specific G-protein-coupled receptors and signal cellular responses, e.g., inflammation, vasodilation, blood pressure, pain etc. But never before it was suggested/shown that C 20:5n-3 (and C 22:6 n-3 ) PUFAs, e.g., EPA (and DHA), are transformed into stable aromatic metabolites, DBPs, which elicit a large array of bioactivities in the producer organisms and also control the synthesis and metabolism of arachidonate-derived prostaglandins. The major beneficial effects attributed to EPA and DHA are now found to be largely contributed by DBPs and their aminoacyl conjugates and the dibenzo-α-pyrone-chromoproteins (DCPs). Because of the highly unstable nature of EPA and DHA, when administered, they are metabolized into a large array of uncontrolled products, several of which are systemically undesirable. By contrast, DBPs, because of their stability, perform the biological response modifier (BRM) functions in a directed and sustained way. Many of the biological effects of DBPs described in this invention, were earlier attributed to EPA and DHA,—the precursors of DBPs.

  一项发明提供了有力证据，证明含氧二苯并-α-吡喃酮（DBPs及其共轭物）是希拉吉（阿育吠陀活力剂）的主要生物活性成分，其起源至少部分源自EPA和DHA。早期研究表明，在哺乳动物中，C-20多不饱和脂肪酸通过氧化酶和其他酶代谢，产生短寿命的前列腺素、白三烯和血栓素，这些物质结合特定的G蛋白偶联受体并传递细胞反应，如炎症、血管舒张、血压、疼痛等。但以前从未提出/展示过C20:5n-3（和C22:6 n-3）多不饱和脂肪酸，如EPA（和DHA），会转化为稳定的芳香代谢物DBPs，这些物质在生产者生物体中引发大量生物活性，并且还控制花生四烯酸衍生的前列腺素的合成和代谢。现在，归因于EPA和DHA的主要益处效应在很大程度上是由DBPs及其氨酰共轭物和二苯并-α-吡喃酮-色蛋白（DCPs）贡献的。由于EPA和DHA的高度不稳定性，当其被施用时，它们会代谢成大量无法控制的产物，其中一些在全身上是不可取的。相比之下，由于其稳定性，DBPs以有针对性和持续的方式执行生物反应调节剂（BRM）功能。本发明描述的DBPs的许多生物效应，以前被归因于EPA和DHA，即DBPs的前体。