2-tert-butyl-1-naphthoic acid | 32338-71-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-tert-butyl-1-naphthoic acid
• 英文别名: 2-(t-butyl)naphthalene-1-carboxylic acid；2-Tert-butylnaphthalene-1-carboxylic acid
• CAS: 32338-71-9
• 化学式: C₁₅H₁₆O₂
• 分子量: 228.291
• InChiKey: WESUCKAJZHODFI-UHFFFAOYSA-N

物化性质

• 沸点：
  385.0±21.0 °C(Predicted)
• 密度：
  1.125±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-甲氧基-1-萘甲酸 、 叔丁基锂 以 四氢呋喃 、 正戊烷 为溶剂， 反应 2.0h， 以87%的产率得到2-tert-butyl-1-naphthoic acid
  参考文献：
  名称：

  未保护的萘甲酸上的邻锂/羧酸镁驱动的芳香亲核取代反应

  摘要：

  在不需要金属催化剂的情况下，与烷基/乙烯基/芳基有机锂和格利雅试剂反应后，提供取代萘酸的1-萘甲酸和2-萘甲酸中的邻氟或甲氧基取代反应的收率非常好。保护羧基（CO 2 H）。据推测，该新的亲核芳族取代是通过有机金属与底物的预配位，然后添加/消除来进行的。

  DOI：

  10.1021/jo202017z

文献信息

• METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP
  申请人：Mortier Jacques

  公开号：US20120316337A1

  公开（公告）日：2012-12-13

  Method for preparing carboxylic acid derivatives by aromatic nucleophilic substitution, in which a carboxylic acid derivative having a single carboxyl functional group, or one of the salts thereof, the carboxylic acid derivative having, in the ortho position of the carboxyl functional group, a leaving group, which is preferably an atom of fluorine or of chlorine or an alkoxy group, chiral or not, preferably a methoxy group, the carboxylic acid derivative not being substituted by an electro attractive group other than the leaving group if any; is reacted with a reactant MNu, where M is a metal and Nu is a nucleophile, chiral or not, the aromatic nucleophilic substitution reaction being carried out without a catalyst and without a step of protecting/deprotecting the acid functional group of the starting compound.

  通过芳香亲核取代法制备羧酸衍生物的方法，其中羧酸衍生物具有单个羧基官能团，或其盐之一，该羧酸衍生物在羧基官能团的邻位具有一个离去基团，该离去基团优选为氟原子或氯原子或烷氧基，手性或非手性，优选为甲氧基，如果有的话，该羧酸衍生物未被电子亲合基团取代；与反应物MNu发生反应，其中M为金属，Nu为亲核试剂，手性或非手性，芳香亲核取代反应在无催化剂和无保护/去保护起始化合物的酸官能团的步骤的情况下进行。
• NONAQUEOUS INKJET INK COMPOSITION
  申请人：Dai Nippon Toryo Co., Ltd.

  公开号：EP2157143B1

  公开（公告）日：2017-03-08
• NON-AQUEOUS INK JET INK COMPOSITION
  申请人：Shiotani Toshihiko

  公开号：US20100056679A1

  公开（公告）日：2010-03-04

  A nonaqueous inkjet ink composition that at printing by an inkjet printer, is free from clogging of a nozzle of printer head part and that excels in ink delivery stability leading to prints of excellent printing quality. The nonaqueous inkjet ink composition is one containing a pigment, a resin, a pigment dispersant, an organic solvent and an aminated alcohol, characterized in that the content of the aminated alcohol is in the range of 0.01 to 3 mass % based on the whole mass. The nonaqueous inkjet ink composition may be one characterized in that the water extract from the nonaqueous inkjet ink composition exhibits a pH value ranging from 6.0 to 10.0.
• Nonaqueous Inkjet Ink Composition
  申请人：Kotera Takehiro

  公开号：US20110009537A1

  公开（公告）日：2011-01-13

  Disclosed is a nonaqueous inkjet ink composition having excellent ink ejection stability, which does not clog a nozzle of a printer head portion when used for printing by an inkjet printer, thereby enabling achievement of a printed matter having excellent print quality. The nonaqueous inkjet ink composition is characterized by containing a pigment, a resin, a pigment dispersing agent, an organic solvent, and additionally a rust inhibitor.
• ACTIVE ESTER RESIN, THERMOSETTING RESIN COMPOSITION, CURED PRODUCT OF SAME, SEMICONDUCTOR ENCAPSULATION MATERIAL, PREPREG, CIRCUIT BOARD, AND BUILD-UP FILM
  申请人：DIC Corporation

  公开号：US20150118499A1

  公开（公告）日：2015-04-30

  A cured product exhibits good heat resistance and flame retardancy as well as low dielectric constant and low loss tangent. A phosphorus-containing compound (i) obtained by a reaction between an aromatic aldehyde (a1) having an alkoxy group as a substituent on a nucleus and an organic phosphorus compound (a2) having a P—H group or a P—OH group in a molecular structure is reacted with a phenolic substance (a3) to obtain a phosphorus-containing phenolic substance (A1). Then the phosphorus-containing phenolic substance (A1) is reacted with an aromatic dicarboxylic acid or an anhydride or dihalide of an aromatic dicarboxylic acid or a C2-6 saturated dicarboxylic acid or an anhydride or dihalide of a C2-6 saturated dicarboxylic acid (A2) so that all or some of hydroxyl groups of the phenolic substance (A1) form ester bonds.