p-bis(dichlorophenylsilyl)-2,2'-benzene | 853-16-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: p-bis(dichlorophenylsilyl)-2,2'-benzene
• 英文别名: Si,Si,Si',Si'-tetrachloro-Si,Si'-diphenyl-Si,Si'-p-phenylene-bis-silane；Si,Si,Si',Si'-Tetrachlor-Si,Si'-diphenyl-Si,Si'-p-phenylen-bis-silan；1,4-Bis-(dichlor-phenyl-silyl)-benzol；1.4-Bis--benzol；1.4-Bis--benzol；(1,4-Phenylene)bis[dichloro(phenyl)silane]；dichloro-[4-[dichloro(phenyl)silyl]phenyl]-phenylsilane
• CAS: 853-16-7
• 化学式: C₁₈H₁₄Cl₄Si₂
• 分子量: 428.292
• InChiKey: HYWDHVRLYZZVHB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.75
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  p-bis(dichlorophenylsilyl)-2,2'-benzene 在 水 作用下， 以 乙醚 为溶剂， 生成 2,4,6,8-tetraphenyl-3,7-dioxa-2,4,6,8-tetrasila-1,5(1,4)-dibenzena-cyclooctaphane-2,4,6,8-tetraol
  参考文献：
  名称：

  Synthesis of organosilicon compounds containing phenylenesiloxane molecular chains

  摘要：

  DOI：

  10.1007/bf01131056
• 作为产物：
  描述：

  二苯二氯硅烷 在 三氯化铝 作用下， 生成 p-bis(dichlorophenylsilyl)-2,2'-benzene
  参考文献：
  名称：

  Radio-frequency transmission line

  摘要：

  公开号：

  US02557781A1

文献信息

• Fischer,E. et al., Journal fur praktische Chemie (Leipzig 1954), 1963, vol. 21, p. 149 - 162
  作者：Fischer,E. et al.

  DOI：——

  日期：——
• Increased incidence of diabetes mellitus in the patients with transitional cell carcinoma of urinary bladder
  作者：Sergey Kravchick、Rivka Gal、Shmuel Cytron、Ronit Peled、Yona Weissman、Eliahu Mukamel、Rumelia Koren

  DOI：10.1007/bf03032606

  日期：2001.3

  The progression of bladder cancer to invasive disease is highly dependent on its ability to penetrate basement membrane of urothelium. Studies on diabetic nephropathy have shown a reduction in proteoglycan content of the glomerular basement membrane. Based on the well-known fact that proteoglycans are one of the main components of basement membrane and extracellular matrix we assessed the relationship between diabetes mellitus, bladder cancer incidence and its behavior. These studies include 252 patients with microscopically confirmed transitional cell carcinoma of bladder, and 549 patients with other urological disorders who served as controls. The prevalence of diabetes mellitus in each group was assessed. The group of patients suffering from transitional cell carcinoma was divided according to etiological risk factors such as cigarette smoking, diabetes and patients that were non-smokers and did not suffer from diabetes mellitus. We assessed the features of bladder cancer behavior in each group. Logistic regression model estimation for statistical analysis was used, with transitional cell carcinoma as a dependent binary variable and age, sexes smoking and diabetes as independent variables. Statistical significance was considered at two levels: p <or=0.001 and p <or=0.05. Odds ratio (OR) adjusted to age, sex, cigarette smoking, diabetes mellitus and 95% Confidence Interval (CI) were calculated for TCC. In the TCC group 22.2% of the patients suffered from diabetes mellitus. In the control group 10.38% suffered from diabetes mellitus. Logistic regression analysis, OR and 95% CI showed a statistically significant relationship between diabetes and TCC. These data are comparable only with smoking (OR 2.3; 95% CI 1.6 3.5 and OR 1.58; 95% CI 1.08 2.4 correspondingly). Based on these data we suggest that diabetes mellitus may be considered an etiological risk factor for bladder cancer development.
• Bochkarev, V. N.; Turetskaya, R. A.; Troitskaya, N. N., Journal of general chemistry of the USSR, 1983, vol. 53, # 4, p. 722 - 725
  作者：Bochkarev, V. N.、Turetskaya, R. A.、Troitskaya, N. N.、Luskina, B. M.、Savushkina, V. I.、et al.

  DOI：——

  日期：——
• Synthesis of novel bithiophene derivatives with an organosilanylene bridge, and their applications to electron-transporting materials in EL devices
  作者：Joji Ohshita、Hiroyuki Kai、Tomohisa Sumida、Atsutaka Kunai、Akira Adachi、Koichi Sakamaki、Koichi Okita

  DOI：10.1016/s0022-328x(01)01257-8

  日期：2002.1

  Compounds having two bithiophene units linked by an organosilicon bridge were prepared. Their UV spectra and cyclic voltammograms indicated that the compounds have the low-lying LUMO. The electron transporting properties of the present silicon-bridged bithiophene derivatives were evaluated by the performance of electroluminescent (EL) devices having vapor deposited silicon-bridged bithiophenes, Alq, and TPD layers, as the electron-transport. emitter and hole-transport, respectively. By applying the bias voltage on the devices, the devices emitted green EL originated from the Alq emission with the maximum luminance of 8500 cd m (2). (C) 2002 Elsevier Science B.V. All rights reserved.
• MELADZE S. M.; MUKBANIANI O. V.; MAKAROVA N. N.; KOYAVA N. A.; XANANASHVI+, SAKARTVELOS CCP METSNIEREBATA AKADEMIIS MOAMBE, SOOBSHCH. AN GRUZSSR, 198+
  作者：MELADZE S. M.、 MUKBANIANI O. V.、 MAKAROVA N. N.、 KOYAVA N. A.、 XANANASHVI+

  DOI：——

  日期：——