trans-crotonaldehyde phenylimine | 55108-06-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: trans-crotonaldehyde phenylimine
• 英文别名: trans-Crotonaldehyd-phenylimin；(E)-N-phenylbut-2-en-1-imine
• CAS: 55108-06-0；71309-67-6
• 化学式: C₁₀H₁₁N
• 分子量: 145.204
• InChiKey: XEMHLSLRQWJZDD-ZTHQVDJGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  12.4
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  trans-crotonaldehyde phenylimine 、 甲基锂 在 水 、 氯化铵 作用下， 以 四氢呋喃 、 乙醚 为溶剂， 以91%的产率得到N-(1-methyl-2-butenyl)aniline
  参考文献：
  名称：

  A modular approach to α,β-unsaturated N-aryl ketonitrones

  摘要：

  A modular approach to alpha,beta-unsaturated N-aryl ketonitrones has been developed. Specifically, condensation of anilines and enals followed by alkylation of the resulting alpha,beta-unsaturated imines provided N-allyl anilines, which were subjected to oxidation with Oxone (R) to form alpha,beta-unsaturated N-aryl ketonitrones. This modular approach is general and provides rapid access to diversely substituted alpha,beta-unsaturated N-aryl ketonitrones with a single purification step in good yields. (c) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2012.06.083
• 作为产物：
  描述：

  巴豆醛 、 苯胺 生成 trans-crotonaldehyde phenylimine
  参考文献：
  名称：

  Ardaschew; Kurbatow, Zhurnal Obshchei Khimii, 1946, vol. 16, p. 54

  摘要：

  DOI：

文献信息

• A modular approach to α,β-unsaturated N-aryl ketonitrones
  作者：Tyler S. Hood、C. Bryan Huehls、Jiong Yang

  DOI：10.1016/j.tetlet.2012.06.083

  日期：2012.8

  A modular approach to alpha,beta-unsaturated N-aryl ketonitrones has been developed. Specifically, condensation of anilines and enals followed by alkylation of the resulting alpha,beta-unsaturated imines provided N-allyl anilines, which were subjected to oxidation with Oxone (R) to form alpha,beta-unsaturated N-aryl ketonitrones. This modular approach is general and provides rapid access to diversely substituted alpha,beta-unsaturated N-aryl ketonitrones with a single purification step in good yields. (c) 2012 Elsevier Ltd. All rights reserved.
• Ardaschew; Kurbatow, Zhurnal Obshchei Khimii, 1946, vol. 16, p. 54
  作者：Ardaschew、Kurbatow

  DOI：——

  日期：——