2-[4-(1-Methylpyridin-1-ium-4-yl)pyridin-1-ium-1-yl]ethanol | 33985-73-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2-[4-(1-Methylpyridin-1-ium-4-yl)pyridin-1-ium-1-yl]ethanol
• CAS: 33985-73-8
• 化学式: C₁₃H₁₆N₂O
• 分子量: 216.283
• InChiKey: IEFIPYCPABTBPE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  28
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  N-甲基-4,4'-联吡啶鎓碘化物 、 alkaline earth salt of/the/ methylsulfuric acid 以 乙腈 为溶剂， 反应 0.17h， 以61%的产率得到2-[4-(1-Methylpyridin-1-ium-4-yl)pyridin-1-ium-1-yl]ethanol
  参考文献：
  名称：

  Microwave-assisted synthesis of symmetric and asymmetric viologens

  摘要：

  Viologens are generally synthesized by N-alkylating 4,4'-bipyridine with alkyl halides. Under conventional heating conditions, however, their synthesis suffers from long reaction times and, often, low yields. In this work, symmetric and asymmetric viologens were synthesized under the assistance of microwave irradiation in good to excellent yields and in short reaction times. (c) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.08.070

文献信息

• Solid herbicidal compositions containing a bipyridinium quaternary salt
  申请人：Merck & Co., Inc.

  公开号：EP0174101B1

  公开（公告）日：1989-10-18
• Microwave-assisted synthesis of symmetric and asymmetric viologens
  作者：Massimiliano Lamberto、Elizabeth E. Rastede、Justyne Decker、Françisco M. Raymo

  DOI：10.1016/j.tetlet.2010.08.070

  日期：2010.10

  Viologens are generally synthesized by N-alkylating 4,4'-bipyridine with alkyl halides. Under conventional heating conditions, however, their synthesis suffers from long reaction times and, often, low yields. In this work, symmetric and asymmetric viologens were synthesized under the assistance of microwave irradiation in good to excellent yields and in short reaction times. (c) 2010 Elsevier Ltd. All rights reserved.