bis(dimethyl-phosphinoylmethyl)-amine | 212781-65-2

• 分子结构分类: 有机化合物 - 有机磷化合物 - 有机膦及其衍生物
• 英文名称: bis(dimethyl-phosphinoylmethyl)-amine
• 英文别名: 1-(Dimethylphosphoryl)-N-[(dimethylphosphoryl)methyl]methanamine；1-dimethylphosphoryl-N-(dimethylphosphorylmethyl)methanamine
• CAS: 212781-65-2
• 化学式: C₆H₁₇NO₂P₂
• 分子量: 197.154
• InChiKey: IKHVLQASOKGAEU-UHFFFAOYSA-N

物化性质

• 沸点：
  429.4±30.0 °C(Predicted)
• 密度：
  1.067±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.7
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  46.2
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  环己基异硫氰酸脂 、 bis(dimethyl-phosphinoylmethyl)-amine 以 氯仿 为溶剂， 反应 0.25h， 以97%的产率得到1-cyclohexyl-3,3-bis(dimethyl-phosphinoylmethyl)thiourea
  参考文献：
  名称：

  Urea and Thiourea Derivatives of Bis(dimethyl-phosphinoylmethyl)-amine

  摘要：

  A group of hitherto unknown 1-aryl-3,3-bis(dimethylphosphinoylmethyl)-, 1-benzyl-3,3-bis(dimethyl-phosphinoylmethyl)and 1-cyclohexyl-3,3-bis(dimethyl-phosphinoylmethyl) ureas and thioureas 1-10 have been synthesized, characterized, and are reported in this article. The compounds were prepared via reaction of corresponding isocyanates or isothiocyanates with the secondary phosporus-containing amine: bis(dimethyl-phosphinoylmethyl)-amine. The composition of the novel compounds was proved by elemental analysis, corresponding structures were confirmed by IR, H-1-, P-31-, P-31 {H-1}-NMR spectroscopy and by mass spectrometry.

  DOI：

  10.1080/10426500211707
• 作为产物：
  描述：

  二甲基磷酰甲胺 、 氯甲基(二甲基)氧膦 在 三乙胺 作用下， 以 苯 为溶剂， 反应 20.0h， 以52%的产率得到bis(dimethyl-phosphinoylmethyl)-amine
  参考文献：
  名称：

  Varbanov; Tosheva; Russeva, Phosphorus, Sulfur and Silicon and the Related Elements, 1997, vol. 127, p. 27 - 37

  摘要：

  DOI：

文献信息

• LUMINESCENT PROBES FOR BIOLOGICAL LABELING AND IMAGING, METHOD FOR PREPARING SAME
  申请人：UNIVERSITE DE STRASBOURG

  公开号：US20140228553A1

  公开（公告）日：2014-08-14

  The present invention relates to organic compounds that are usable as ligands for preparing complexes of lanthanides or of certain transition metals which are water-soluble, to a method for preparing same, and also to the use thereof as a fluorescent probe.

  本发明涉及作为配体用于制备镧系元素或某些过渡金属的水溶性配合物的有机化合物，涉及制备方法以及将其用作荧光探针的用途。
• LUMINESCENT PROBES FOR BIOLOGICAL LABELING AND IMAGING, AND PROCESS FOR PREPARING THE SAME
  申请人：CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

  公开号：US20140213777A1

  公开（公告）日：2014-07-31

  The present invention relates to organic compounds, usable as ligands in the preparation of lanthanide complexes or of certain water-soluble transition metals, a method for preparation thereof, and the use of said organic compounds as fluorescent probes.

  本发明涉及有机化合物，可用作配体制备镧系化合物或某些水溶性过渡金属，其制备方法以及将所述有机化合物用作荧光探针的用途。
• US9328088B2
  申请人：——

  公开号：US9328088B2

  公开（公告）日：2016-05-03
• US9388202B2
  申请人：——

  公开号：US9388202B2

  公开（公告）日：2016-07-12