methyl orthobenzoate | 282548-08-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: methyl orthobenzoate
• 英文别名: Methoxy(phenyl)methanediol
• CAS: 282548-08-7
• 化学式: C₈H₁₀O₃
• 分子量: 154.166
• InChiKey: BITWOIDYUNBQGQ-UHFFFAOYSA-N

物化性质

• 沸点：
  143.7±35.0 °C(Predicted)
• 密度：
  1.238±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  49.7
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  三氯化苄 在 sodium methylate 作用下， 以51%的产率得到methyl orthobenzoate
  参考文献：
  名称：

  Processes for neutralizing 2,3-dibromopropanol phosphoric acid esters

  摘要：

  本发明涉及一种用于中和含有一定量磷酸性和可能含有卤酸性的三（2,3-二溴-1-丙基）磷酸酯的方法，其中所述方法包括将该磷酸酯与至少一种含碳的正酯热处理，由此产生的三（2,3-二溴-1-丙基）磷酸酯适用于作为塑料、合成纤维和涂料的阻燃或防火剂。

  公开号：

  US04059656A1

文献信息

• [EN] PARTICLES, COMPOSITIONS, AND METHODS FOR OPHTHALMIC AND/OR OTHER APPLICATIONS<br/>[FR] PARTICULES, COMPOSITIONS ET PROCÉDÉS POUR APPLICATIONS OPHTALMIQUES ET/OU AUTRES APPLICATIONS
  申请人：KALA PHARMACEUTICALS INC

  公开号：WO2019055028A1

  公开（公告）日：2019-03-21

  This disclosure relates to particles, compositions, and methods that aid particle transport in mucus are provided. The particles, compositions, and methods may be used, in some instances, for ophthalmic and/or other applications.

  本公开涉及有助于粘液中颗粒传输的颗粒、组合物和方法。这些颗粒、组合物和方法在某些情况下可用于眼科和/或其他应用。
• Process for Preparing 4-Aminopyrimidine Compound
  申请人：Nishino Shigeyoshi

  公开号：US20080045712A1

  公开（公告）日：2008-02-21

  The present invention is to provide a process for preparing a 4-aminopyrimidine compound represented by the formula (3): wherein R 1 and R 2 each represent a hydrogen atom or group which does not participate in the reaction and which may have a substituent(s), and R 1 and R 2 may be bonded to each other to form a ring, and R 4 represents a hydrogen atom or a hydrocarbon group, which comprises reacting ammonia, a 3-substituted or unsubstituted acrylonitrile compound represented by the formula (1): CR 1 (CN)═CR 2 Y  (1) wherein R 1 and R 2 have the same meanings as defined above, and Y represents an amino group or OR, where R represents a hydrogen atom or a hydrocarbon group, and an organic acid compound represented by the formula (2): (R 3 O) 3 CR 4 (2) wherein R 3 represents a hydrocarbon group, and R 4 has the same meaning as defined above.

  本发明提供了一种制备由以下式表示的4-氨基嘧啶化合物的方法（3）：其中R1和R2分别表示参与反应的氢原子或基团，可能具有取代基，且R1和R2可以相互连接形成环，R4表示氢原子或烃基，包括将氨、由以下式表示的3-取代或未取代的丙烯腈化合物（1）：CR1(CN)═CR2Y（1）与由以下式表示的有机酸化合物（2）反应：（R3O）3CR4（2）。其中R1和R2的含义如上定义，Y表示氨基或OR，其中R表示氢原子或烃基，R3表示烃基，R4的含义如上定义。
• 6 Alpha-methylprednisolone derivatives
  申请人：OHTA SEIYAKU KABUSHIKI KAISHA.

  公开号：EP0095894A2

  公开（公告）日：1983-12-07

  A 6a-methylprednisolone derivative of the general formula: wherein R' is a hydrogen atom or the group where R3 is a straight or once-branched chain C1-4 alkyl group, a phenyl group or a lower alkoxy- or alkylthio-methyl group, and R2 is a straight or once-branched chain C1-4 alkyl group, a phenyl group or a lower alkoxy- or alkylthio-methyl group, with the proviso that when R2 is ethyl group, R1 is not a hydrogen atom or a propionyl group. These compounds exhibit a strong local anti-inflammatory effect and so are useful in external anti-inflammatory preparations for the treatment of various dermal disorders and also as anti-allergic drugs for the treatment of asthma and other allergic diseases.

  通式如下的 6a-甲基泼尼松龙衍生物 其中 R' 是氢原子或基团 其中 R3 是直链或一度支链 C1-4 烷基、苯基或低级烷氧基或烷基硫代甲基，R2 是直链或一度支链 C1-4 烷基、苯基或低级烷氧基或烷基硫代甲基，但当 R2 为乙基时，R1 不是氢原子或丙酰基。 这些化合物具有很强的局部消炎作用，因此可用于治疗各种皮肤病的外用消炎制剂，也可用作治疗哮喘和其他过敏性疾病的抗过敏药物。
• Method for decomposing polysiloxane
  申请人：Kanegafuchi Chemical Industry Co., Ltd.

  公开号：EP0687679A1

  公开（公告）日：1995-12-20

  When a polysiloxane or siloxane is contacted with a mixture which comprises an orthoester, a compound having an active hydrogen-containing group and an acid catalyst, it is easily decomposed even at room temperature to provide a silicon compound having a lower molecular weight such as an alkoxysilane.

  当聚硅氧烷或硅氧烷与由原酯、具有活性含氢基团的化合物和酸催化剂组成的混合物接触时，即使在室温下也很容易分解，生成分子量较低的硅化合物，例如烷氧基硅烷。
• POLYACETAL RESIN COMPOSITION
  申请人：Asahi Kasei Kabushiki Kaisha

  公开号：EP3981834A1

  公开（公告）日：2022-04-13

  The present disclosure is directed to provide a polyacetal resin composition which reduces mold contaminations, formaldehyde released from molded articles, and occurrence of foreign matters in the molded articles, even when the molded articles are produced under conditions where the materials are exposed to a high temperature for long time. A polyacetal resin composition of the present disclosure contains: a polyacetal resin (A); and a semi-aromatic polyamide resin (B) which contains a dicarboxylic acid unit containing 75 mol% or more of an isophthalic acid unit, and a diamine unit containing 50 mol% or more of a diamine unit having a carbon number of 4 to 10, and has a number average molecular weight Mn of 3,000 or more and 20,000 or less.

  本公开旨在提供一种聚缩醛树脂组合物，该组合物可减少模具污染、模塑制品释放的甲醛以及模塑制品中异物的发生，即使模塑制品是在材料长时间暴露于高温的条件下生产的。本公开的聚缩醛树脂组合物包含：聚缩醛树脂（A）；和半芳香族聚酰胺树脂（B），后者包含二羧酸单元，其中异酞酸单元的含量为 75 摩尔%或以上，二胺单元，其中二胺单元的含量为 50 摩尔%或以上，二胺单元的碳数为 4 至 10，平均分子量 Mn 为 3,000 或以上 20,000 或以下。