Original synthesis of 2-substituted-4,11-dimethoxy-1-(phenylsulfonyl)-2,3-dihydro-1H-naphtho[2,3-f]indole-5,10-diones using TDAE and Cu-catalyzed reaction strategy
作者:Omar Khoumeri、Gamal Giuglio-Tonolo、Maxime D. Crozet、Thierry Terme、Patrice Vanelle
DOI:10.1016/j.tet.2011.06.069
日期:2011.8
We report herein an original and rapid synthesis of 2-substituted-4,11-dimethoxy-1-(phenylsulfonyl)-2,3-dihydro-1H-naphtho[2,3-f]indole-5,10-diones by TDAE mediated synthesis of N-benzylsulfonamides followed by an intramolecular N-arylation using Cu-catalyzed system. (C) 2011 Elsevier Ltd. All rights reserved.