(N,N-diphenyl-N-thio)-1,3-propanediamine | 952488-47-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (N,N-diphenyl-N-thio)-1,3-propanediamine
• 英文别名: 3-(3-Aminopropyl)-1,1-diphenylthiourea；3-(3-aminopropyl)-1,1-diphenylthiourea
• CAS: 952488-47-0
• 化学式: C₁₆H₁₉N₃S
• 分子量: 285.413
• InChiKey: ULYAVSKIIFUIOP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  73.4
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (N,N-diphenyl-N-thio)-1,3-propanediamine 、 nickel diacetate 以 盐酸 、 甲醇 为溶剂， 生成 Ni((N,N-diphenyl-N-thio)-1,3-propanediamine)2(CH3CO2)2
  参考文献：
  名称：

  Nickel(II) thiohydrazide and thiodiamine complexes: Synthesis, characterization, antibacterial, antifungal and thermal studies

  摘要：

  Nickel(II) complexes of type [Ni(L)(2)Cl-2] and [Ni(L)(2)(OCOCH3)(2)], where L = N,N-diphenyl-N-thiohydrazide (L-1) and (N,N-diphenyl-N-thio)-1,3-propanediamine (L-2), have been synthesized. The thiodiamines coordinate as a bidentate N-S ligand. The synthesized nickel(II) complexes of the thiodiamines were characterized by elemental analysis, IR, mass, electronic and H-1 NMR spectroscopic and TG/DTA studies. Various kinetic and thermodynamic parameters like order of reaction (n), activation energy (E-a), apparent activation entropy (S-#) and heat of reaction (Delta H) have also been carried out for one complex. These complexes were also screened for in vitro antifungal and in vitro antibacterial activities and significant activity have been found. (c) 2007 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2007.05.046
• 作为产物：
  描述：

  、 1,3-丙二胺 以 甲醇 为溶剂， 反应 0.75h， 生成 (N,N-diphenyl-N-thio)-1,3-propanediamine
  参考文献：
  名称：

  Nickel(II) thiohydrazide and thiodiamine complexes: Synthesis, characterization, antibacterial, antifungal and thermal studies

  摘要：

  Nickel(II) complexes of type [Ni(L)(2)Cl-2] and [Ni(L)(2)(OCOCH3)(2)], where L = N,N-diphenyl-N-thiohydrazide (L-1) and (N,N-diphenyl-N-thio)-1,3-propanediamine (L-2), have been synthesized. The thiodiamines coordinate as a bidentate N-S ligand. The synthesized nickel(II) complexes of the thiodiamines were characterized by elemental analysis, IR, mass, electronic and H-1 NMR spectroscopic and TG/DTA studies. Various kinetic and thermodynamic parameters like order of reaction (n), activation energy (E-a), apparent activation entropy (S-#) and heat of reaction (Delta H) have also been carried out for one complex. These complexes were also screened for in vitro antifungal and in vitro antibacterial activities and significant activity have been found. (c) 2007 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2007.05.046

文献信息

• Mishra; Mishra; Mamba, Polish Journal of Chemistry, 2009, vol. 83, # 6, p. 1085 - 1098
  作者：Mishra、Mishra、Mamba、Chhillar、Kaushik

  DOI：——

  日期：——
• Nickel(II) thiohydrazide and thiodiamine complexes: Synthesis, characterization, antibacterial, antifungal and thermal studies
  作者：A.K. Mishra、N.K. Kaushik

  DOI：10.1016/j.saa.2007.05.046

  日期：2008.3

  Nickel(II) complexes of type [Ni(L)(2)Cl-2] and [Ni(L)(2)(OCOCH3)(2)], where L = N,N-diphenyl-N-thiohydrazide (L-1) and (N,N-diphenyl-N-thio)-1,3-propanediamine (L-2), have been synthesized. The thiodiamines coordinate as a bidentate N-S ligand. The synthesized nickel(II) complexes of the thiodiamines were characterized by elemental analysis, IR, mass, electronic and H-1 NMR spectroscopic and TG/DTA studies. Various kinetic and thermodynamic parameters like order of reaction (n), activation energy (E-a), apparent activation entropy (S-#) and heat of reaction (Delta H) have also been carried out for one complex. These complexes were also screened for in vitro antifungal and in vitro antibacterial activities and significant activity have been found. (c) 2007 Elsevier B.V. All rights reserved.