3-[hydroxy(p-methylphenyl)phosphinyl]propionic acid | 20417-25-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-[hydroxy(p-methylphenyl)phosphinyl]propionic acid
• 英文别名: 3-[Hydroxy-(4-methylphenyl)phosphoryl]propanoic acid
• CAS: 20417-25-8
• 化学式: C₁₀H₁₃O₄P
• 分子量: 228.185
• InChiKey: ZJPIRJDIPFYVAW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  p-tolyldichlorophosphine 以94%的产率得到3-[hydroxy(p-methylphenyl)phosphinyl]propionic acid
  参考文献：
  名称：

  Method of producing a phosphinyl-carboxylic acid derivative

  摘要：

  根据上述反应，可以在选择的有机过氧化物和偶氮化合物的催化剂存在下，使具有以下一般式（I）的膦衍生物与丙烯酸或甲基丙烯酸发生反应，然后用水水解得到以下一般式（III）的膦酰基羧酸衍生物。根据上述反应，还可以获得游离酸和环酸酐的酯。因此，目标化合物可以在相对较低的反应温度下，在短时间内以高产率获得。反应基本上是定量进行的，从而提高了生产率并便于纯化。

  公开号：

  US05334760A1

文献信息

• POLYESTER RESIN, POLYESTER RESIN COMPOSITION THEREFROM AND USE THEREOF
  申请人：Togawa Keiichiro

  公开号：US20090297752A1

  公开（公告）日：2009-12-03

  A polyester resin that can be beneficially employed as one finding application in deactivation of polycondensation catalysts for polyester production and suppression of forming of acetaldehyde and other aldehydes and cyclic ester oligomers at molding stage. In particular, there is provided a polyester resin composed mainly of an aromatic dicarboxylic acid component and a glycol component wherein a phosphorus compound is incorporated through copolymerization or blending in an amount of 100 to 10,000 ppm in terms of phosphorus element, characterized in that the contents of Zn element, Fe element, Ni element and Cr element are not greater than specified values.
• US5334760A
  申请人：——

  公开号：US5334760A

  公开（公告）日：1994-08-02
• Method of producing a phosphinyl-carboxylic acid derivative
  申请人：Sakai Chemical Industry Co., Ltd.

  公开号：US05334760A1

  公开（公告）日：1994-08-02

  A phosphine derivative of the following general formula ( I ): ##STR1## (wherein R.sup.1 is an alkyl group having 1 to 18 carbon atoms or an aryl group having 6 to 18 carbon atoms, and the aryl group may have an alkyl group having 1 to 18 carbon atoms or an alkenyl group having 2 to 18 carbon atoms) is reacted with acrylic acid or methacrylic acid in the presence of a catalyst selected from the group consisting of an organic peroxide and an azo-compound, and the resulting reaction product is hydrolyzed with water, thereby to obtain a phosphinyl-carboxylic acid derivative of the following general formula (III): ##STR2## (wherein R.sup.1 is as defined above, and R.sup.2 is a hydrogen atom or a methyl group). Based on the reaction above-mentioned, ester of free acid and a cyclic acid anhydride can also be obtained. Accordingly, the target compound can be obtained at a relatively low reaction temperature in a short period of time with high yield. The reaction proceeds substantially quantitatively, thus enhancing the productivity and facilitating the purification.

  根据上述反应，可以在选择的有机过氧化物和偶氮化合物的催化剂存在下，使具有以下一般式（I）的膦衍生物与丙烯酸或甲基丙烯酸发生反应，然后用水水解得到以下一般式（III）的膦酰基羧酸衍生物。根据上述反应，还可以获得游离酸和环酸酐的酯。因此，目标化合物可以在相对较低的反应温度下，在短时间内以高产率获得。反应基本上是定量进行的，从而提高了生产率并便于纯化。