diethyl 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctylphosphonate | 350608-55-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机膦酸及其衍生物
• 英文名称: diethyl 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctylphosphonate
• 英文别名: diethyl 1H,1H,2H,2H-tridecafluorooctyl-phosphonate；(3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctyl)phosphonic acid diethyl ester；8-diethoxyphosphoryl-1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorooctane
• CAS: 350608-55-8
• 化学式: C₁₂H₁₄F₁₃O₃P
• 分子量: 484.194
• InChiKey: YPQKUXRTMVAZPK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  29
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  16

反应信息

• 作为反应物：
  描述：

  diethyl 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctylphosphonate 在 吡啶 、 氢溴酸 作用下， 反应 7.0h， 生成 2-[dimetyl(octyl)ammonio]ethyl 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctylphosphonate
  参考文献：
  名称：

  Novel fluorinated dialkylphosphonatocholines: Synthesis, physicochemical properties and antiprotozoal activities against Acanthamoeba spp.

  摘要：

  The synthesis of four new organophosphorous gemini surfactants is presented. They belong to the class of dialkylphosphonatocholines. Tails are represented with two octyl groups both non or partially fluorinated. The synthesis was performed by reaction of alkylphosphonic acids with choline derivatives in the presence of 2,4,6-triisopropylbenzenesulfonyl chloride. The micellar, surface active, and solubilization properties of new surfactants were studied. Antiprotozoal activities were tested against Acanthamoeba lugdunensis and Acanthamoeba quina. (C) 2014 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2014.04.008
• 作为产物：
  描述：

  2-溴乙基膦酸二乙酯 在 偶氮二异丁腈 、 三正丁基氢锡 、 potassium hydroxide 作用下， 以 乙醇 为溶剂， 反应 17.25h， 生成 diethyl 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctylphosphonate
  参考文献：
  名称：

  Novel fluorinated dialkylphosphonatocholines: Synthesis, physicochemical properties and antiprotozoal activities against Acanthamoeba spp.

  摘要：

  The synthesis of four new organophosphorous gemini surfactants is presented. They belong to the class of dialkylphosphonatocholines. Tails are represented with two octyl groups both non or partially fluorinated. The synthesis was performed by reaction of alkylphosphonic acids with choline derivatives in the presence of 2,4,6-triisopropylbenzenesulfonyl chloride. The micellar, surface active, and solubilization properties of new surfactants were studied. Antiprotozoal activities were tested against Acanthamoeba lugdunensis and Acanthamoeba quina. (C) 2014 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2014.04.008

文献信息

• COATED METAL OXIDE NANOPARTICLES AND METHODS FOR PRODUCING SAME
  申请人：Perry Joseph

  公开号：US20100027192A1

  公开（公告）日：2010-02-04

  Disclosed are coated metal oxide nanoparticles comprising a metal oxide nanoparticle having a surface; and ligands attached to the metal oxide nanoparticle surface. Also disclosed are phosphonic acid compounds comprising the structure Gn-R-Xn, wherein G is a terminal group; wherein R is a bridging group; wherein X is a phosphonic acid group; and wherein each n is, independently, 1, 2, or 3. Also disclosed are methods for preparing and using coated metal oxide nanoparticles. Also disclosed are nanocomposite compositions comprising a polymer; and a coated metal oxide nanoparticle dispersed within the polymer. Also disclosed are articles, films, and capacitors comprising a coated metal oxide nanoparticle or a nanocomposite composition. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  揭示了包含具有表面的金属氧化物纳米颗粒的涂层金属氧化物纳米颗粒；以及附着在金属氧化物纳米颗粒表面的配体。还揭示了包含结构Gn-R-Xn的膦酸化合物，其中G是末端基团；其中R是桥接基团；其中X是膦酸基团；每个n独立地为1、2或3。还揭示了制备和使用涂层金属氧化物纳米颗粒的方法。还揭示了包含聚合物的纳米复合材料组合物；以及分散在聚合物中的涂层金属氧化物纳米颗粒。还揭示了包含涂层金属氧化物纳米颗粒或纳米复合材料组合物的制品、薄膜和电容器。本摘要旨在作为在特定领域进行搜索的扫描工具，并不打算限制本发明。
• Efficient Syntheses of Fluorous Primary Phosphines that Do Not Require PH₃
  作者：J. A. Gladysz、Charlotte Emnet

  DOI：10.1055/s-2005-861815

  日期：——

  Arbuzov reactions of the fluorous primary iodides Rfn(CH2)mI [Rfn = CF3(CF2)n-1; n/m = 6/2, 8/2, 8/3, 10/2] and P(OEt)3 (excess, 160 °C) give the fluorous phosphonates Rfn(CH2)mP(O)(OEt)2 (56-59%), which are reduced with LiAlH4 to the title compounds Rfn(CH2)mPH2 (62-78%). Fluorophilicities (CF3C6F11/toluene partition coefficients) increase with the length of the Rfn moiety, decrease with the length of the (CH2)m moiety, and decrease in the functional group sequence Rfn(CH2)mNH2 > Rfn(CH2)mPH2 > Rfn(CH2)mP(O)(OEt)2.

  Arbuzov反应中，氟化的一级碘化物Rfn(CH2)mI [Rfn = CF3(CF2)n-1; n/m = 6/2, 8/2, 8/3, 10/2]与P(OEt)3（过量，160°C）反应生成氟化磷酸酯Rfn(CH2)mP(O)(OEt)2（收率为56-59%），随后用LiAlH4还原为标题化合物Rfn(CH2)mPH2（收率为62-78%）。氟亲和性（CF3C6F11/甲苯分配系数）随着Rfn部分的长度增加而增加，随着(CH2)m部分的长度增加而减小，并且在功能团序列中呈现递减趋势：Rfn(CH2)mNH2 > Rfn(CH2)mPH2 > Rfn(CH2)mP(O)(OEt)2。
• Nickel(0)-Catalyzed Fluoroalkylation of Alkenes, Alkynes, and Aromatics with Perfluoroalkyl Chlorides
  作者：Xiao-Ting Huang、Qing-Yun Chen

  DOI：10.1021/jo010178j

  日期：2001.6.1

  Treatment of perfluoroalkyl chlorides (R(F)Cl) with alkenes, alkynes, or aromatics in the presence of 0.1 equiv of nickel dichloride, 1.5 equiv of zinc powder, and 0.4 equiv of triphenylphosphine in DMF at 95-100 degrees C for 6-8 h give the corresponding perfluoroalkylated products in good yields. A single electron-transfer mechanism is suggested.

  在95至100摄氏度的DMF中，在0.1当量的二氯化镍，1.5当量的锌粉和0.4当量的三苯膦存在下，用烯烃，炔烃或芳烃处理全氟烷基氯化物（R（F）Cl），在6-100 8小时以良好的产率得到相应的全氟烷基化产物。提出了单电子转移机理。
• PRINTABLE THIN-FILM TRANSISTORS WITH HIGH DIELECTRIC CONSTANT GATE INSULATORS AND METHODS FOR PRODUCING SAME
  申请人：Kippelen Bernard

  公开号：US20100051917A1

  公开（公告）日：2010-03-04

  Disclosed are embodiments of organic thin-film transistors (OTFT) with a gate insulator layer comprised of nanocomposites incorporating metal oxide nanoparticles coated by organic ligands and methods of fabricating such OTFTs. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  本发明涉及一种有机薄膜晶体管（OTFT），其栅介质层由包含有机配体涂覆的金属氧化物纳米颗粒的纳米复合材料组成，并且涉及制造此类OTFT的方法。本摘要旨在作为搜索特定技术领域的扫描工具，不限制本发明。
• Printable thin-film transistors with high dielectric constant gate insulators and methods for producing same
  申请人：Kippelen Bernard

  公开号：US08405069B2

  公开（公告）日：2013-03-26

  Disclosed are embodiments of organic thin-film transistors (OTFT) with a gate insulator layer comprised of nanocomposites incorporating metal oxide nanoparticles coated by organic ligands and methods of fabricating such OTFTs. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  本发明公开了有机薄膜晶体管（OTFT）的实施例，其栅绝缘层由包含有机配体包覆的金属氧化物纳米颗粒的纳米复合材料组成，并公开了制造这样的OTFT的方法。本摘要旨在作为搜索特定技术领域的扫描工具，不限制本发明。