4-Hydroxypyrene-1,2,3-trisulfonic acid | 112803-18-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 芘
• 英文名称: 4-Hydroxypyrene-1,2,3-trisulfonic acid
• CAS: 112803-18-6
• 化学式: C₁₆H₁₀O₁₀S₃
• 分子量: 458.4
• InChiKey: MTYHUTYJKFVTJJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  29
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  209
• 氢给体数：
  4
• 氢受体数：
  10

文献信息

• Optical determination of glucose utilizing boronic acid adducts
  申请人：——

  公开号：US20040028612A1

  公开（公告）日：2004-02-12

  The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vitro and/or in vivo in aqueous media. In particular, a sensory devise is implemented in a mammal to determine sugar levels. Specifically, a dye is combined with a conjugated nitrogen-containing heterocyclic aromatic boronic acid-substituted bis-onium compound in the presence of a sugar, such as fructose or glucose. The viologens are preferred as the aromatic conjugated nitrogen-containing boronic acid substituted compounds. The method is useful to determine sugar levels in a human being.

  本发明涉及一种改进的光学方法和光学传感器设备，用于在体内和/或体外的水介质中确定多羟基取代有机分子的水平。特别地，实施了一种感应器设备在哺乳动物体内以确定糖的水平。具体地，在存在糖（如果糖或葡萄糖）的情况下，将染料与共轭氮杂芳基硼酸取代的双阳离子化合物结合。芘啉是偏好的芳香族共轭氮杂芳基硼酸取代化合物。该方法对于确定人类体内的糖水平是有用的。
• FLUORESCENT DYE FOR PH SENSOR
  申请人：Riechers Daniel

  公开号：US20140080222A1

  公开（公告）日：2014-03-20

  The present invention relates to a new type of fluorescent with the following formula (I), its preparation process, and also an optical pH sensor which comprises this fluorescent dye immobilized on an analyte-permeable carrier.

  本发明涉及一种具有以下式（I）的新型荧光剂，其制备过程，以及包括这种荧光染料固定在可渗透分析物载体上的光学pH传感器。
• Intracorporeal substance measuring assembly
  申请人：Kawanishi Tetsuro

  公开号：US20050221277A1

  公开（公告）日：2005-10-06

  An intracorporeal substance measuring assembly to be provided in an embedded-type substance sensor for detecting and measuring an intercorporeal analyte includes: a detection layer containing at least one fluorescent indicator for generating fluorescence according to the concentration of the analyte; and an optical separation layer which is provided on the detection layer, is optically opaque, permits the analyte to penetrate therethrough, and prevents the penetration therethrough of at least one of living body substances possibly deteriorating the detection layer and/or obstructing the fluorescence.

  一种用于嵌入式物质传感器的体内物质测量组件，用于检测和测量体内分析物，包括：检测层，其中包含至少一种荧光指示剂，根据分析物的浓度产生荧光；以及光学隔离层，该层位于检测层上，光学不透明，允许分析物穿透，防止至少一种可能会恶化检测层和/或阻碍荧光的生物体物质穿透。
• Method for the Determination of the Concentration of a Non-Volatile Analyte
  申请人：Leiner Marco Jean-Pierre

  公开号：US20080215254A1

  公开（公告）日：2008-09-04

  The invention relates to a method for the determination of the concentration of a non-volatile analyte in an aqueous sample medium, with the use of an optical sensor which contains a luminescent dye and is calibrated at the user site by means of a single-point-calibration. To enable the user to completely dispense with all calibration media a luminescence measurement value is obtained at the user site with the sensor in contact with the aqueous or bloodlike sample medium, which value is referenced to the relative characteristic obtained at the factory site and to a measured dry calibration value obtained at the user site, the concentration of the non-volatile analyte being deduced from these data.

  本发明涉及一种使用光学传感器测定水样介质中非挥发性分析物浓度的方法，该传感器包含发光染料，并通过单点校准在用户现场进行校准。为了使用户完全不需要使用任何校准介质，使用传感器与水性或类似血样的样品介质接触，在用户现场获取荧光测量值，该值参考了在工厂现场获得的相对特征和在用户现场获得的干燥校准值，从而推导出非挥发性分析物的浓度。
• OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS
  申请人：SINGARAM Bakthan

  公开号：US20120009126A1

  公开（公告）日：2012-01-12

  The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vitro and/or in vivo in aqueous media. The range of detection is between about 400 and 800 nm. In particular, a sensory devise is implemented in a mammal to determine sugar levels. Specifically, a dye is combined with a conjugated nitrogen-containing heterocyclic aromatic boronic acid-substituted bis-onium compound in the presence of a sugar, such as fructose or glucose. The viologens are preferred as the aromatic conjugated nitrogen-containing boronic acid substituted compounds. The method is useful to determine sugar levels in a human being.

  本发明涉及一种改进的光学方法和光学传感器装置，用于在体内和/或体外的水介质中确定多羟基取代有机分子的水平。检测范围在大约400到800纳米之间。特别地，实施了一种传感器装置在哺乳动物中，以确定糖的水平。具体地，将染料与含有硼酸取代的氮杂环芳香基双阳离子化合物结合，在存在糖，如果糖或葡萄糖的情况下。偏好使用紫罗兰作为芳香性共轭氮取代硼酸化合物。该方法对于确定人体内的糖水平非常有用。