thioacetic acid S-(6-bromohexyl) ester | 479072-66-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 硫代羧酸及其衍生物
• 英文名称: thioacetic acid S-(6-bromohexyl) ester
• 英文别名: 6-bromohexyl thioacetate；6-bromohexyl ethanethioate；S-(6-bromohexyl) ethanethioate；6-(acetylthio)-1-bromohexane
• CAS: 479072-66-7
• 化学式: C₈H₁₅BrOS
• 分子量: 239.177
• InChiKey: NLHXLQGFUZRCGN-UHFFFAOYSA-N

物化性质

• 沸点：
  272.9±23.0 °C(Predicted)
• 密度：
  1.293±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  11
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  42.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  thioacetic acid S-(6-bromohexyl) ester 在 potassium carbonate 、 三乙胺 作用下， 以 甲醇 、 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 反应 19.0h， 生成 methyl 3-[(6-{2-amino-6-[2-(trimethylsilyl)ethoxy]-9H-purin-9-yl}hexyl)thio]-2-(iodomethyl)-2-methylpropanoate
  参考文献：
  名称：

  摘要：

  The vitamin-B-12 derivative 11, incorporating a peripheral N-4-acetylcytosine moiety, was alkylated under, guanine reductive conditions with 2-(iodomethyl)-2-methylmonothiomalonate 8 bearing the complementary moiety. The reaction yielded a mixture of vitamin-B-12-derived complexes with variations in the cytosine moiety: products 16-18 with a cytosine, a N-4-acetylated cytosine and a N-4-acetylated reduced cytosine moiety were formed (see Scheme 5). The complexes were photolyzed in CHCl3/MeCN to yield the dimethylmalonate derivative 22 (Scheme 6) but not the rearranged succinate, in contrast to the results obtained earlier with complexes incorporating the A(.)T base pair (see Scheme 1).

  DOI：

  10.1002/1522-2675(200209)85:9<3002::aid-hlca3002>3.0.co;2-b
• 作为产物：
  描述：

  6-溴正己醇 、 硫代乙酸 在 三苯基膦 、 偶氮二甲酸二乙酯 作用下， 生成 thioacetic acid S-(6-bromohexyl) ester
  参考文献：
  名称：

  带有一或两个硫醇功能的基于四硫富瓦烯的豆荚：固定为自组装单层或聚合物薄膜，并具有识别特性

  摘要：

  介绍了基于四硫富瓦烯的受体的各种硫醇和二硫醇衍生物的合成，以及它们作为自组装单分子膜（SAMs）固定在金上的方法。TTF-二硫醇衍生物的电氧化也表明了包含TTF单元的膜的形成。证明了单层电化学识别Pb 2+的能力。

  DOI：

  10.1016/j.tet.2006.02.054

文献信息

• Racemic thioesters for production of polyketides
  申请人：Kosan Biosciences, Inc.

  公开号：US06492562B1

  公开（公告）日：2002-12-10

  Facile methods for preparing diketide and triketide thioesters are disclosed. The resulting thioesters may be used as intermediates in the synthesis of desired polyketides, and may contain functional groups which ultimately reside in side chains on the resulting polyketide and thus can be used further to manipulate the polyketide so as form derivatives. The polyketides produced may also be tailored by glycosylation, hydroxylation and the like. New polyketides and their derivatives and tailored forms are thereby produced.

  披露了制备二酮和三酮硫酯的简便方法。所得的硫酯可以用作合成所需多酮化合物的中间体，并且可能含有最终存在于所得多酮化合物侧链上的功能基团，因此可以进一步用于操纵多酮化合物以形成衍生物。通过糖基化、羟基化等方法，还可以定制生产的多酮化合物。因此，生产了新的多酮化合物及其衍生物和定制形式。
• ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORBENCY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAME
  申请人：Miyoshi Oil & Fat Co., Ltd.

  公开号：US20170217937A1

  公开（公告）日：2017-08-03

  Provided is an additive for imparting ultraviolet absorbency, or an additive for imparting a high refractive index, which has satisfactory compatibility with a resin serving as a matrix and can maintain high transparency even if added in high concentrations. Also provided is an additive with which the function of imparting both ultraviolet absorbency and a high refractive index can be realized by means of one kind of additive. This additive is represented by the following Formula (I): wherein at least one of R 1a to R 9a is a monovalent sulfur-containing group represented by the following Formula (i-1) or Formula (i-2): wherein R 10a to R 12a each represent a divalent hydrocarbon group or the like; and R 13a represents a monovalent hydrocarbon group or the like.

  提供了一种用于赋予紫外线吸收性能的添加剂，或者用于赋予高折射率的添加剂，该添加剂与作为基体的树脂具有良好的相容性，并且即使在高浓度下添加也能保持高透明度。还提供了一种通过一种添加剂实现赋予紫外线吸收性能和高折射率功能的添加剂。该添加剂由以下式（I）表示：其中R1至R9中至少有一个是由以下式（i-1）或式（i-2）表示的一价含硫基团：其中R10至R12分别表示二价碳氢基团或类似物；R13表示一价碳氢基团或类似物。
• Preparation and Photoelectrochemical Properties of a Self-Assembled Monolayer of a Ruthenium Tris(2,2′-bipyridine)-viologen 1:2 Linked Compound
  作者：Nao Terasaki、Tsuyoshi Akiyama、Sunao Yamada

  DOI：10.1246/cl.2000.668

  日期：2000.6

  A ruthenium tris(2,2′-bipyridine)-viologen 1:2 linked disulfide was prepared. A gold electrode modified with this compound showed a higher efficiency of photocurrent as compared with a corresponding 1:1 linked compound.

  制备了钌三(2,2'-联吡啶)-紫精1:2连接的二硫化物。与相应的 1:1 连接化合物相比，用这种化合物修饰的金电极显示出更高的光电流效率。
• Plasmon Resonance Scattering Spectroscopy at the Single-Nanoparticle Level: Real-Time Monitoring of a Click Reaction
  作者：Lei Shi、Chao Jing、Wei Ma、Da-Wei Li、Jonathan E. Halls、Frank Marken、Yi-Tao Long

  DOI：10.1002/anie.201301930

  日期：2013.6.3

  A method based on plasmon resonance Rayleigh scattering (PRRS) spectroscopy and dark‐field microscopy (DFM) was established for the real‐time monitoring of a click reaction at the single‐nanoparticle level. Click reactions on the surface of single gold nanoparticles (GNPs) result in interparticle coupling, which leads to a red‐shift of the λmax (Δλmax=43 nm) in the PRRS spectra and a color change of

  建立了基于等离振子共振瑞利散射（PRRS）光谱和暗场显微镜（DFM）的方法，用于在单纳米颗粒水平上实时监测点击反应。点击的单个的金纳米颗粒（的GNP）结果在颗粒间的耦合，在表面上的反应，这导致所述的红移λ最大（Δ λ最大值在PRRS光谱= 43纳米），并在单个的金纳米颗粒的颜色变化DFM（从绿色到橙色）。
• Studies of hybrid organic–inorganic [2] and [3]rotaxanes bound to Au surfaces
  作者：Harapriya Rath、Grigore A. Timco、Valdis Corradini、Alberto Ghirri、Umberto del Pennino、Antonio Fernandez、Robin G. Pritchard、Christopher A. Muryn、Marco Affronte、Richard E. P. Winpenny

  DOI：10.1039/c3cc38699f

  日期：——

  Hybrid organic–inorganic [2]- and [3]rotaxanes have been synthesised, and their ability to bind to Au surfaces studied; the length of the tethering group is found to control how the supramolecular assembly binds to the surface and we find that [2]rotaxanes show improved stability over previous studies of simple inorganic rings.

  我们合成了杂化有机无机[2]-和[3]轮烷，并研究了它们与金表面结合的能力；我们发现系链基团的长度可以控制超分子组装体与金表面的结合方式，而且我们发现[2]轮烷的稳定性比以前对简单无机环的研究有所提高。