1,2-dichloro-phenazine | 3368-42-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 1,2-dichloro-phenazine
• 英文别名: 1,2-Dichlor-phenazin；1,2-Dichlorphenazin；1,2-Dichlorophenazine
• CAS: 3368-42-1
• 化学式: C₁₂H₆Cl₂N₂
• 分子量: 249.099
• InChiKey: MUYSJCZHNQPDNG-UHFFFAOYSA-N

物化性质

• 熔点：
  175-177 °C
• 沸点：
  422.3±15.0 °C(Predicted)
• 密度：
  1.482±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  25.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,2-dichloro-phenazine 在 甲醇 、 sodium methylate 作用下， 生成 2-acetoxy-1-chloro-phenazine
  参考文献：
  名称：

  Tschernezkii, Zhurnal Obshchei Khimii, 1957, vol. 27, p. 2833,2835; engl. Ausg. S. 2869, 2871

  摘要：

  DOI：
• 作为产物：
  描述：

  1,2-dichloro-phenazine 5-oxide 在 乙酸酐 、 N,N-二甲基苯胺 作用下， 生成 1,2-dichloro-phenazine
  参考文献：
  名称：

  Otomasu, Pharmaceutical Bulletin, 1955, vol. 3, p. 365,368

  摘要：

  DOI：

文献信息

• An improved electrochromic medium capable of producing a pre-selected color
  申请人：Gentex Corporation

  公开号：EP1457813A2

  公开（公告）日：2004-09-15

  An electrochromic device, comprising: front and rear spaced elements each having front and rear surfaces; a layer of conductive material disposed on said rear surface of said front element and said front surface of said rear element, and a perimeter sealing member that defines a chamber between said front and rear spaced elements,    where said chamber contains an electrochromic medium, said electrochromic medium comprising at least three electroactive materials, at least two of which are electrochromic, where the redox potentials of all of said electroactive materials that are anodic are within about 200 mV of one another, and wherein the redox potentials of all of said electroactive materials that are cathodic are within about 200 mV of one another.

  电致变色装置，包括 前、后间隔元件，每个元件都有前、后表面； 一层导电材料，放置在所述前部元件的后表面和所述后部元件的前表面上，以及一个周边密封部件，在所述前部和后部间隔元件之间形成一个腔室、 其中，所述腔室包含电致变色介质，所述电致变色介质包括至少三种电活性材料，其中至少两种是电致变色材料，所有所述电活性材料的阳极氧化还原电位彼此相差约 200 mV，所有所述电活性材料的阴极氧化还原电位彼此相差约 200 mV。
• Tschernezkii; Kiprianow, Zhurnal Obshchei Khimii, 1953, vol. 23, p. 1743,1749;engl.Ausg.S.1839,1843
  作者：Tschernezkii、Kiprianow

  DOI：——

  日期：——
• TADA MASAO, BULL. CHEM. SOC. JAP., 1978, 51, NO 10, 3093-3094
  作者：TADA MASAO

  DOI：——

  日期：——
• AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR
  申请人：GENTEX CORPORATION

  公开号：EP0972227A1

  公开（公告）日：2000-01-19
• TREATMENT OF ADDICTION AND DEPENDENCY
  申请人：Taca, JR. Arturo C.

  公开号：US20220072311A1

  公开（公告）日：2022-03-10

  The present invention relates to methods of treating or preventing addiction and relapse use of addictive agents where the method comprises: (a) administering to a subject a co-therapy treatment with an auricular or peri-auricular electro-acupuncture or neurostimulation device, (b) co-treatment with at least one non-narcotic detoxification agent and (c) administering to the subject an opioid antagonist. The methods and compositions of the invention are useful in the treatment or prevention of addiction to any agent, including alcohol, nicotine, marijuana, cocaine, and amphetamines, as well as compulsive and addictive behaviors, including pathological gambling and pathological overeating.

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