2,2,3-trimethyl-2,3-dihydro-4H-furo[3,2-c][1]benzopyran-4-one | 31581-57-4

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: 2,2,3-trimethyl-2,3-dihydro-4H-furo[3,2-c][1]benzopyran-4-one
• 英文别名: 2,2,3-trimethyl-2,3-dihydrofuro[3,2-c]chromen-4-one；2,2,3-trimethyl-3H-furo[3,2-c]chromen-4-one
• CAS: 31581-57-4
• 化学式: C₁₄H₁₄O₃
• 分子量: 230.263
• InChiKey: VFBVRRYFJWIBOM-UHFFFAOYSA-N

物化性质

• 熔点：
  85-86 °C
• 沸点：
  364.2±31.0 °C(Predicted)
• 密度：
  1.23±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  17
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  4-(3',3'-dimethylallyloxy)coumarin 生成 2,2,3-trimethyl-2,3-dihydro-4H-furo[3,2-c][1]benzopyran-4-one
  参考文献：
  名称：

  GONZALEZ, GONZALEZ, A.;DIAZ, CHICO, E.;JORGE, Z. D.;LOPEZ, DORTA, H.;RODR+, AN. QUIM. PUBL. REAL. SOC. ESP. FIS. Y QUIM., 1981, 77, N 1, 63-66

  摘要：

  DOI：

文献信息

• In(OTf)₃-catalysed easy access to dihydropyranocoumarin and dihydropyranochromone derivatives
  作者：Naouel Boufroua、Elisabet Dunach、Fabien Fontaine-Vive、Samia Achouche-Bouzroura、Sophie Poulain-Martini

  DOI：10.1039/d0nj00080a

  日期：——

  Allylation/cyclization of β-ketolactone-type heterocyclic compounds, under In(OTf)₃-catalysis, for the construction of biologically active dihydropyranocoumarin and dihydropyranochromone derivatives.

  β-酮内酯类杂环化合物的烯丙基化/环化反应，在In(OTf)₃催化下进行，用于构建具有生物活性的二氢吡喃香豆素和二氢吡喃色酮衍生物。
• CAN-mediated Formation of Furopyranones and Furoquinolinones
  作者：Kazuhiro Kobayashi、Kouji Sakashita、Hideki Akamatsu、Koujirou Tanaka、Masaharu Uchida、Tomokazu Uneda、Taichi Kitamura、Osamu Morikawa、Hisatoshi Konishi

  DOI：10.3987/com-99-8688

  日期：——

  The reaction of 4-hydroxy-2H-pyran-2-one derivatives (1), (11), and (17) with a range of alkenes or phenylacetylene in acetonitrile containing cerium(IV) ammonium nitrate (CAN) afforded the corresponding furo[3,2-c]pyranone (4, 8, 13, 15, and 18) and/or furo[2,3-b]pyranone derivatives (6, 10, 14, 16, and 19). Similar treatment of 4-hydroxy-1-methylquinolin-2(1H)-one (2) with alkenes or phenylacetylene in the presence of CAN gave furo[3,2-c]quinolin-4(5H)-one derivatives (5) and (9).
• Photoinduced molecular transformations. 100. Formation of furocoumarins and furochromones via a .beta.-scission of cyclobutanoxyl radicals generated from [2 + 2] photoadducts from 4-hydroxycoumarin and acyclic and cyclic alkenes. X-ray crystal structures of benzocyclopentacyclobutapyranone, cyclopentafurobenzopyranone, and benzocyclobutapyranone derivatives
  作者：Hiroshi Suginome、Chi Fu Liu、Shinzo Seko、Kazuhiro Kobayashi、Akio Furusaki

  DOI：10.1021/jo00260a027

  日期：1988.12
• SUGINOME, HIROSHI;LIU, CHI FU;SEKO, SHINZO;KOBAYASHI, KAZUHIRO;FURUSAKI, +, J. ORG. CHEM., 53,(1988) N5, C. 5952-5959
  作者：SUGINOME, HIROSHI、LIU, CHI FU、SEKO, SHINZO、KOBAYASHI, KAZUHIRO、FURUSAKI, +

  DOI：——

  日期：——
• SHAH R. R.; TRIVEDI K. N., CURR. SCI (INDIA) <CUSC-AM>, 1975, 44, NO 7, 226-227
  作者：SHAH R. R.、 TRIVEDI K. N.

  DOI：——

  日期：——