triethylphosphonium hydrochloride

• 分子结构分类: 有机化合物 - 有机磷化合物 - 有机膦及其衍生物
• 英文名称: triethylphosphonium hydrochloride
• 英文别名: Triethylphosphonium chloride salt；triethylphosphanium;chloride
• 化学式: C₆H₁₆P*Cl
• 分子量: 154.62
• InChiKey: NXPYHCCOHHNZNF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.95
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  1
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  triethylphosphonium hydrochloride 、 苯甲醇 反应 8.0h， 生成 triethylbenzylphosphonium bromide
  参考文献：
  名称：

  An iterative approach toward the synthesis of discrete oligomeric p-phenylene vinylene organic dyes employing aqueous Wittig chemistry

  摘要：

  Photovoltaic research has become increasingly prominent as the search for alternatives to fossil fuels are actively sought. A novel process for the iterative synthesis of discrete donor/acceptor-flanked oligostilbenes, key constituents in dye-sensitized solar cells, is described. The aqueous Wittig process is high yielding, proceeds with high (E)-stereoselectivity and allows facile product purification. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.08.040
• 作为产物：
  描述：

  三乙基膦 在 盐酸 作用下， 以 乙醚 、 水 为溶剂， 反应 0.08h， 以98%的产率得到triethylphosphonium hydrochloride
  参考文献：
  名称：

  钒氧代亚烷基配合物的合成及其在闭环烯烃复分解反应中的反应性

  摘要：

  Viimido 亚烷基已被用于涉及环烯烃的开环复分解聚合反应。然而，由于对乙烯的不稳定性，这些配合物在与无环末端烯烃的反应中的应用受到限制。实验和理论研究表明，未取代金属环丁烯的 β-氢化物消除是这些系统中的主要分解途径。在此，我们报告的第一催化活性V的合成氧代亚烷基，VO（CHSiMe 3）（PET 3）2氯，其显示出与已知的V催化剂中闭环复分解反应的各种末端烯烃最高报生产率。提出的 DFT 研究表明，β-氢化物消除明显不利于 V oxo 物种。

  DOI：

  10.1021/acs.organomet.1c00425

文献信息

• Ring‐Closing Olefin Metathesis Catalyzed by Well‐Defined Vanadium Alkylidene Complexes
  作者：Dmitry S. Belov、Gabriela Tejeda、Charlene Tsay、Konstantin V. Bukhryakov

  DOI：10.1002/chem.202005438

  日期：2021.3.8

  selectivity in ring‐opening metathesis polymerization of strained cyclic olefins comparable to those of Ru, Mo, and W catalysts. However, the application of V alkylidenes in routine organic synthesis is limited. Here, we present the first example of ring‐closing olefin metathesis catalyzed by well‐defined V chloride alkylidene phosphine complexes. The developed catalysts exhibit tolerance to various functional

  钒基催化剂在应变环烯烃的开环易位聚合中显示出与Ru，Mo和W催化剂相当的活性和选择性。但是，在常规的有机合成中V亚烷基的应用受到限制。在这里，我们给出了由明确定义的V氯化物亚烷基膦配合物催化的开环烯烃复分解的第一个例子。所开发的催化剂表现出对各种官能团的耐受性，所述官能团例如醚，酯，叔酰胺，叔胺和磺酰胺。亚胺基和膦的大小和给电子性质在活性中间体的稳定性中起着至关重要的作用。
• METHOD FOR PREPARING QUATERNARY PHOSPHONIUM SALTS
  申请人：Microvast Power Systems Co.,Ltd.

  公开号：US20150166587A1

  公开（公告）日：2015-06-18

  A two-step pathway for preparing high pure quaternary phosphonium salts is disclosed. In the first step, hydrogen phosphide (PH 3 ) or a higher phophine reacts with a protonic compound to produce a phosphonium salt, which then reacts with a carbonic acid diester to produce a quaternary phosphonium salt in the second step. On one hand, hydrogen phosphide (PH 3 ) and higher phophines, including primary phosphines, secondary phosphines, and tertiary phosphines, after neutralization with protonic compound, become sufficiently reactive and can be alkylated by carbonic acid diester to form quaternary phosphonium cations. On the other hand, as an anion-exchange procedure is completely avoided, the process not only gives quaternary phosphonium salts of high purity, but also gives people freedom to design the cation and the anion of a quaternary phosphonium salt synchronously by choosing a preferred phosphine and a protonic compound that can supply a desired anion.

  揭示了一种制备高纯度四元磷铵盐的两步途径。在第一步中，氢磷化物（PH3）或更高的磷化物与质子化合物发生反应，产生磷铵盐，然后在第二步中与碳酸二酯发生反应，产生四元磷铵盐。一方面，氢磷化物（PH3）和更高的磷化物，包括一次磷化物、二次磷化物和三次磷化物，在与质子化合物中和后变得足够活性，可以被碳酸二酯烷基化形成四元磷铵阳离子。另一方面，由于完全避免了阴离子交换程序，该过程不仅提供高纯度的四元磷铵盐，还使人们可以通过选择理想的磷化物和可以提供所需阴离子的质子化合物，同时设计四元磷铵盐的阳离子和阴离子。
• A Tandem “On-Palladium” Heck-Jeffery Amination Route Toward the Synthesis of Functionalized Indole-2-carboxylates
  作者：James McNulty、Kunal Keskar

  DOI：10.1002/ejoc.201101072

  日期：2011.12

  A direct synthesis of functionalized indole-2-carboxylates involving a PdII-catalyzed annulation of ortho-iodoanilines onto a vinyl ether is described. The reaction mechanism is shown to be distinct from a stepwise Heck, intramolecular amination pathway, likely involving a tandem “on-palladium” Heck–Jeffery amination process incorporating a novel intramolecular amination step.

  描述了一种直接合成功能化的 indole-2-carboxylates，包括 PdII 催化的邻碘苯胺环化到乙烯基醚上。该反应机制与逐步 Heck 分子内胺化途径不同，可能涉及串联的“钯上”Heck-Jeffery 胺化过程，并结合了新的分子内胺化步骤。
• Methods and compositions providing enhanced chemiluminescence from
  申请人：Lumigen, Inc.

  公开号：US05451347A1

  公开（公告）日：1995-09-19

  A dicationic surfactant for enhancing the chemiluminescence of chemiluminescent compounds particularly dioxetanes which are triggerable is described. The surfactant has the formula X.sup.- (R.sub.1).sub.3 A.sup.+ CH.sub.2 --Link--CH.sub.2 A.sup.+ (R.sub.2).sub.3 X.sup.- wherein A is selected from the group consisting of phosphorus and nitrogen atoms separately or together, wherein X is an anionic counterion and R.sub.1 and R.sub.2 are selected from the group consisting of unsubstituted and substituted alkyl and aralkyl groups containing 1 to 20 carbon atoms and R.sub.1 and R.sub.2 can be the same or different, and wherein Link is a carbon chain group selected from the group consisting of dialkylenearyl, aryl, alkylene, alkenylene and alkynylene groups containing 4 to 20 carbon atoms. The surfactants are particularly useful in Western and Southern blot assays.

  本发明涉及一种双阳离子表面活性剂，用于增强化学发光化合物的化学发光性能，特别是可触发的二氧杂环烷类化合物。该表面活性剂的化学式为X.sup.- (R.sub.1).sub.3 A.sup.+ CH.sub.2 --Link--CH.sub.2 A.sup.+ (R.sub.2).sub.3 X.sup.-，其中A选自磷和氮原子，分别或同时存在；X为阴离子计数离子；R.sub.1和R.sub.2选自含1至20个碳原子的未取代和取代的烷基和芳基烷基；R.sub.1和R.sub.2可以相同也可以不同；Link是选择自含4至20个碳原子的双烷基芳基、芳基、烷基、烯基和炔基的碳链基团。该表面活性剂在Western和Southern印迹分析中特别有用。
• Optically Active 4,4-Di-Substituted Oxazolidine Derivative and Method for Producing Same
  申请人：Onoda Toshihiko

  公开号：US20080108828A1

  公开（公告）日：2008-05-08

  An optically active 4,4-di-substituted oxazolidine compound having the formula (I) wherein R 1 represents a substituted C 1 -C 3 alkyl group, a substituted C 2 -C 3 alkenyl group, a formyl group, a hydroxymethyl group, a group of the formula COOR, a halogenated methyl group, a phosphonium methyl group; R represents a C 1 -C 6 alkyl group, a C 2 -C 6 alkenyl group, a phenyl group or a benzyl group; R 2 represents a C 1 -C 6 alkyl group, a C 3 -C 10 cycloalkyl group, or the like or a phenyl group; R 3 represents a C 2 -C 6 alkanoyl group, a C 1 -C 6 alkyloxycarbonyl group, a benzoyl group, a phenyloxycarbonyl group or a benzyloxycarbonyl group and R 4 represents a C 1 -C 6 alkyl group or a C 2 -C 6 alkenyl group.

  具有式（I）的光学活性4,4-双取代噁唑啉化合物，其中R1代表取代的C1-C3烷基，取代的C2-C3烯基，甲酰基，羟甲基，COOR的配基，卤代甲基，磷甲基；R代表C1-C6烷基，C2-C6烯基，苯基或苄基；R2代表C1-C6烷基，C3-C10环烷基或类似物或苯基；R3代表C2-C6酰基，C1-C6烷氧羰基，苯甲酰基，苯氧羰基或苄氧羰基，R4代表C1-C6烷基或C2-C6烯基。