Visible-Light-Driven Oxidation of N-Alkylamides to Imides Using Oxone/H2O and Catalytic KBr
作者:Wenjun Lu、Chong Mei、Yixin Hu
DOI:10.1055/s-0036-1591575
日期:2018.8
Applications in Synthesis Abstract Imides are prepared conveniently by visible-light-driven oxidations of various N-alkylamides under mild conditions. The majority of the reactions proceed efficiently by using Oxone as the oxidant in the presence of a catalytic amount of KBr in H2O/CH2Cl2 under irradiation by an 8 W white LED at room temperature. Experimental studies suggest that an imine, obtained from the substrate
作为特别主题“现代自由基方法及其在合成中的战略应用”的一部分发布 抽象的 通过在温和条件下可见光驱动的各种N-烷基酰胺的氧化反应可方便地制备酰亚胺。在室温下,在8 W白光LED辐射下,在H 2 O / CH 2 Cl 2中催化量的KBr存在下,使用Oxone作为氧化剂可有效地进行大多数反应。实验研究表明,通过自由基过程从底物酰胺获得的亚胺是关键中间体。 通过在温和条件下可见光驱动的各种N-烷基酰胺的氧化反应可方便地制备酰亚胺。在室温下,在8 W白光LED辐射下,在H 2 O / CH 2 Cl 2中催化量的KBr存在下,使用Oxone作为氧化剂可有效地进行大多数反应。实验研究表明,通过自由基过程从底物酰胺获得的亚胺是关键中间体。
10.1021/acs.orglett.4c01758
作者:Ali, Kashif、Cho, Eun Jin
DOI:10.1021/acs.orglett.4c01758
日期:——
activation. The C–N bond formation under mild reaction conditions, employing NiCl2 as the catalyst and cataCXiumA as a ligand, results in the production of a diverse array of alkylated secondary or tertiary amines, including heterocyclicamines. This method introduces a novel catalytic strategy that emphasizes the versatility of nickel-catalyzed reactions, extending beyond traditional synthetic boundaries