phenylazanediol | 29788-23-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: phenylazanediol
• 英文别名: N,N-dihydroxyaniline
• CAS: 29788-23-6
• 化学式: C₆H₇NO₂
• 分子量: 125.127
• InChiKey: FJJWJAFSUDWTTR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  43.7
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• 3,4-dihydro-2-naphthamide derivatives as selective dopamine D3 ligands
  申请人：INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)

  公开号：EP1683790A1

  公开（公告）日：2006-07-26

  The invention relates to 3,4-dihydro-2-naphthamide derivatives of formula (I), pharmaceutical compositions containing them and their therapeutic applications as partial agonists or antagonists of the dopamine D3 receptor for the treatment of neuropsychological disorders.

  该发明涉及公式(I)的3,4-二氢-2-萘酰胺衍生物，包含它们的药物组合物以及它们作为多巴胺D3受体的部分激动剂或拮抗剂在治疗神经心理障碍方面的治疗应用。
• [EN] MULTI-ARMED CATECHOL COMPOUND BLENDS<br/>[FR] MELANGES DE COMPOSES DE CATECHOL A BRANCHES MULTIPLES
  申请人：NERITES CORP

  公开号：WO2010037045A1

  公开（公告）日：2010-04-01

  The invention describes families of compounds that utilize multihydroxyl phenyl groups to provide adhesive properties. Selection of the multihydroxy phenyl group along with linkers or linking groups and the linkages between the linkers or linking groups with polyalkylene oxides, provides materials that can be engineered to afford controllable curing time, biodegradation and/or swelling.

  该发明描述了一系列利用多羟基苯基团提供粘合性能的化合物家族。选择多羟基苯基团以及连接剂或连接基团以及连接剂或连接基团与聚烷氧化物之间的连接，提供了可以被工程化的材料，以实现可控的固化时间、生物降解和/或肿胀性能。
• Water insoluble derivatives of polyanionic polysaccharides
  申请人：——

  公开号：US20010039336A1

  公开（公告）日：2001-11-08

  A water insoluble, biocompatible composition that is formed by a method which combines, in an aqueous mixture, a polyanionic polysaccharide, a nucleophile, and an activating agent, under conditions sufficient to form the composition. Also, a water insoluble, biocompatible composition that is formed by a method which combines, in an aqueous mixture, a polyanionic polysaccharide, a modifying compound, a nucleophile and an activating agent under conditions sufficient to form the composition.

  一种水不溶性的生物相容性组合物，其通过一种方法形成，该方法在水混合物中结合多阴离子多糖、亲核试剂和活化剂的条件下足以形成该组合物。此外，一种水不溶性的生物相容性组合物，其通过一种方法形成，该方法在水混合物中结合多阴离子多糖、修饰化合物、亲核试剂和活化剂的条件下足以形成该组合物。
• Novel polyimide compositions and novel acid dianhydrides to be used therein
  申请人：KANEKA CORPORATION

  公开号：US20020055610A1

  公开（公告）日：2002-05-09

  Novel polyimides substituted by a substituent having an alkyl or fluoroalkyl group and having reduced water absorption; a process for producing these novel polyimides; and novel acid dianhydrides to be used in the production thereof. A polyimide containing a structure represented by the following general formula (I): 1 wherein X 1 represents a tetravalent organic group having a substituent —R 1 AR 2 (wherein A represents a divalent linkage group; R 1 represents a single bond or a C 1-3 alkylene group; and R 2 represents a C 1-25 alkyl group or a fluoroalkyl group); and Y represents a divalent organic group.

  新型聚酰亚胺，其被取代基含有烷基或氟烷基，且具有降低吸水性；制备这些新型聚酰亚胺的方法；以及用于制备新型聚酰亚胺的新型酸二酐。聚酰亚胺包含以下一般式(I)所表示的结构：1其中，X1代表一个四价有机基团，其具有一个取代基-R1AR2（其中A代表二价连接基；R1代表单键或C1-3烷基；R2代表C1-25烷基或氟烷基）；Y代表二价有机基团。
• Process for preparing ortho substituted phenylamines
  申请人：——

  公开号：US20040162444A1

  公开（公告）日：2004-08-19

  A process is disclosed for preparing ortho substituted phenylamines comprising contacting phenylhydroxylamine, optionally substituted with at least one inert substituent, with a nucleophilic reagent in the presence of a manganese oxide at a temperature between about 10° C. and about 170° C. and a pressure from subatmospheric to superatmospheric such that an ortho substituted phenylamine, optionally correspondingly substituted with at least one inert substituent, is predominantly formed.

  一种制备邻位取代苯胺的方法被披露，包括将苯基羟胺与一种亲核试剂接触，所述苯基羟胺可以选择性地被至少一种惰性取代基取代，并在存在锰氧化物的条件下，在温度约为10℃到170℃之间以亚大气压到超大气压的压力下进行反应，从而主要形成一种邻位取代苯胺，该苯胺可以选择性地相应地被至少一种惰性取代基取代。