2-(methylthio)-5-vinylpyridine | 1190977-43-5

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 2-(methylthio)-5-vinylpyridine
• 英文别名: 5-Ethenyl-2-methylsulfanylpyridine；5-ethenyl-2-methylsulfanylpyridine
• CAS: 1190977-43-5
• 化学式: C₈H₉NS
• 分子量: 151.232
• InChiKey: SIZNUZOZJSTXII-UHFFFAOYSA-N

物化性质

• 沸点：
  256.3±28.0 °C(Predicted)
• 密度：
  1.07±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  38.2
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  溴乙烯 、 6-(甲硫基)吡啶-3-硼酸 在 palladium diacetate 、 三苯基膦 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 反应 1.0h， 以0.78 g的产率得到2-(methylthio)-5-vinylpyridine
  参考文献：
  名称：

  Synthesis of sulfur-containing aryl and heteroaryl vinyls via Suzuki–Miyaura cross-coupling for the preparation of SERS-active polymers

  摘要：

  The preparation of sulfur-containing aryl and heteroaryl vinyl co-monomers via Suzuki-Miyaura cross-coupling between the corresponding mercaptomethyl arylboronates and in situ-generated vinyl bromides is described. Surface-enhanced Raman scattering (SERS) studies of the target compounds on gold nanoparticles confirmed their potential as spectroscopic tags in the fabrication of SERS-encoded polymers for combinatorial screening and biomedical diagnostics. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.07.061

文献信息

• Synthesis of sulfur-containing aryl and heteroaryl vinyls via Suzuki–Miyaura cross-coupling for the preparation of SERS-active polymers
  作者：Rolando Perez-Pineiro、Sheng Dai、Ramon Alvarez-Puebla、James Wigginton、Baker Jawabrah Al-Hourani、Hicham Fenniri

  DOI：10.1016/j.tetlet.2009.07.061

  日期：2009.9

  The preparation of sulfur-containing aryl and heteroaryl vinyl co-monomers via Suzuki-Miyaura cross-coupling between the corresponding mercaptomethyl arylboronates and in situ-generated vinyl bromides is described. Surface-enhanced Raman scattering (SERS) studies of the target compounds on gold nanoparticles confirmed their potential as spectroscopic tags in the fabrication of SERS-encoded polymers for combinatorial screening and biomedical diagnostics. (C) 2009 Elsevier Ltd. All rights reserved.